New Molecular Insights of Insulin in Diabetic Cardiomyopathy (Q26752678)

Europe PubMed Central

title

New Molecular Insights of Insulin in Diabetic Cardiomyopathy (English)

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diabetic cardiomyopathy

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9

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author name string

Francisco Westermeier

1

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Jaime A Riquelme

2

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Mario Pavez

3

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Valeria Garrido

4

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Ariel Díaz

5

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Hugo E Verdejo

6

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Pablo F Castro

7

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Lorena García

8

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language of work or name

English

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publication date

2016

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published in

Frontiers in Physiology

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Insulin resistance and hyperinsulinaemia in diabetic cardiomyopathy

volume

7

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page(s)

125

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cites work

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Adenosine A1 receptor activation attenuates cardiac hypertrophy and fibrosis in response to α1 -adrenoceptor stimulation in vivo.

28 September 2017

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Silencing of miR-195 reduces diabetic cardiomyopathy in C57BL/6 mice

28 September 2017

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28 September 2017

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Insulin receptor substrates are essential for the bioenergetic and hypertrophic response of the heart to exercise training.

28 September 2017

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Cardiomyocytes mediate anti-angiogenesis in type 2 diabetic rats through the exosomal transfer of miR-320 into endothelial cells

28 September 2017

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Progressive decay of Ca2 homeostasis in the development of diabetic cardiomyopathy

28 September 2017

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Insulin inhibits cardiac contractility by inducing a Gi-biased β2-adrenergic signaling in hearts.

28 September 2017

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Molecular mechanisms of diabetic cardiomyopathy.

28 September 2017

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28 September 2017

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Cardiac miR-133a overexpression prevents early cardiac fibrosis in diabetes

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Regulation of fatty acid metabolism by mTOR in adult murine hearts occurs independently of changes in PGC-1α

28 September 2017

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Structural changes in the myocardium during diabetes-induced cardiomyopathy

28 September 2017

1 reference

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28 September 2017

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28 September 2017

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Mechanisms of subcellular remodeling in heart failure due to diabetes

28 September 2017

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28 September 2017

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28 September 2017

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Emerging role of epigenetics and miRNA in diabetic cardiomyopathy

28 September 2017

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Insulin resistance: metabolic mechanisms and consequences in the heart.

28 September 2017

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The A2b adenosine receptor modulates glucose homeostasis and obesity

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Metabolic stress-induced activation of FoxO1 triggers diabetic cardiomyopathy in mice

28 September 2017

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Cytosolic, but not mitochondrial, oxidative stress is a likely contributor to cardiac hypertrophy resulting from cardiac specific GLUT4 deletion in mice

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Excessive cardiac insulin signaling exacerbates systolic dysfunction induced by pressure overload in rodents

28 September 2017

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28 September 2017

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MicroRNA-133 regulates the expression of GLUT4 by targeting KLF15 and is involved in metabolic control in cardiac myocytes

28 September 2017

1 reference

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FoxO transcription factors promote autophagy in cardiomyocytes

28 September 2017

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Impaired insulin signaling accelerates cardiac mitochondrial dysfunction after myocardial infarction

28 September 2017

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28 September 2017

1 reference

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Mechanisms for increased myocardial fatty acid utilization following short-term high-fat feeding

28 September 2017

1 reference

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28 September 2017

1 reference

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Type 1 diabetic akita mouse hearts are insulin sensitive but manifest structurally abnormal mitochondria that remain coupled despite increased uncoupling protein 3.

28 September 2017

1 reference

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Cardiac restricted overexpression of kinase-dead mammalian target of rapamycin (mTOR) mutant impairs the mTOR-mediated signaling and cardiac function

28 September 2017

1 reference

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FoxO transcription factors activate Akt and attenuate insulin signaling in heart by inhibiting protein phosphatases

28 September 2017

1 reference

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A conserved role for phosphatidylinositol 3-kinase but not Akt signaling in mitochondrial adaptations that accompany physiological cardiac hypertrophy.

28 September 2017

1 reference

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28 September 2017

1 reference

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Reduced cardiac efficiency and altered substrate metabolism precedes the onset of hyperglycemia and contractile dysfunction in two mouse models of insulin resistance and obesity.

28 September 2017

1 reference

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The FOXO3a transcription factor regulates cardiac myocyte size downstream of AKT signaling

28 September 2017

1 reference

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Glucose transport in the heart

28 September 2017

1 reference

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Insulin: an endogenous cardioprotector

28 September 2017

1 reference

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Sizing up the heart: development redux in disease.

28 September 2017

1 reference

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A critical role for PPARalpha-mediated lipotoxicity in the pathogenesis of diabetic cardiomyopathy: modulation by dietary fat content.

28 September 2017

1 reference

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Cardiomyocyte cell cycle regulation

28 September 2017

1 reference

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Hyperglycemia-induced apoptosis in mouse myocardium: mitochondrial cytochrome C-mediated caspase-3 activation pathway

28 September 2017

1 reference

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Insulin signaling coordinately regulates cardiac size, metabolism, and contractile protein isoform expression

28 September 2017

1 reference

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The conserved phosphoinositide 3-kinase pathway determines heart size in mice

28 September 2017

1 reference

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An A3-subtype adenosine receptor is highly expressed in rat vascular smooth muscle cells: its role in attenuating adenosine-induced increase in cAMP.

28 September 2017

1 reference

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Evidence that insulin causes translocation of glucose transport activity to the plasma membrane from an intracellular storage site

28 September 2017

1 reference

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New type of cardiomyopathy associated with diabetic glomerulosclerosis

28 September 2017

1 reference

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Expression of a functional human insulin receptor from a cloned cDNA in Chinese hamster ovary cells

28 September 2017

1 reference

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Insulin receptor substrate signaling suppresses neonatal autophagy in the heart.

28 September 2017

1 reference

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Interaction of myocardial insulin receptor and IGF receptor signaling in exercise-induced cardiac hypertrophy

31 May 2018

1 reference

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Foxo transcription factors blunt cardiac hypertrophy by inhibiting calcineurin signaling

31 May 2018

1 reference

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Optical mapping of propagation changes induced by elevated extracellular potassium ion concentration in genetically altered mouse hearts

31 May 2018

1 reference

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Regulation of insulin-responsive aminopeptidase expression and targeting in the insulin-responsive vesicle compartment of glucose transporter isoform 4-deficient cardiomyocytes.

31 May 2018

1 reference

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Early activation of the p42/p44MAPK pathway mediates adenosine-induced nitric oxide production in human endothelial cells: a novel calcium-insensitive mechanism

31 May 2018

1 reference

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Pathological versus physiological left ventricular hypertrophy: a review

31 May 2018

1 reference

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Several factors associated with the insulin resistance syndrome are predictors of left ventricular systolic dysfunction in a male population after 20 years of follow-up

31 May 2018

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Loss of lipoprotein lipase-derived fatty acids leads to increased cardiac glucose metabolism and heart dysfunction.

21 January 2018

1 reference

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An inositol 1,4,5-triphosphate (IP3)-IP3 receptor pathway is required for insulin-stimulated glucose transporter 4 translocation and glucose uptake in cardiomyocytes

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00125

MicroRNA profiling unveils hyperglycaemic memory in the diabetic heart

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00125

Insulin/NFκB protects against ischemia-induced necrotic cardiomyocyte death

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00125

Mouse and human resistins impair glucose transport in primary mouse cardiomyocytes, and oligomerization is required for this biological action.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00125

Insulin resistance and risk of congestive heart failure

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00125

MicroRNA-451 exacerbates lipotoxicity in cardiac myocytes and high-fat diet-induced cardiac hypertrophy in mice through suppression of the LKB1/AMPK pathway.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00125

Insulin stimulates long-chain fatty acid utilization by rat cardiac myocytes through cellular redistribution of FAT/CD36.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00125

Impaired cardiac efficiency and increased fatty acid oxidation in insulin-resistant ob/ob mouse hearts.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00125

Contractile dysfunction in hypertrophied hearts with deficient insulin receptor signaling: possible role of reduced capillary density.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00125

Activation of Foxo1 by insulin resistance promotes cardiac dysfunction and β-myosin heavy chain gene expression.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00125

FoxO3 induces reversible cardiac atrophy and autophagy in a transgenic mouse model.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00125

Akt signaling mediates postnatal heart growth in response to insulin and nutritional status

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00125

Responses of GLUT4-deficient hearts to ischemia underscore the importance of glycolysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00125

Plasma exosomes protect the myocardium from ischemia-reperfusion injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00125

Executive Summary: Heart Disease and Stroke Statistics—2014 Update

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00125

Left Ventricular Diastolic Function in Type 2 Diabetes Mellitus

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FPHYS.2016.00125

Altered expression of adenosine receptors in heart of diabetic rat.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828458

Left ventricular mass and systolic function in African diabetic patients: association with microalbuminuria

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828458

Adenosine A(2A) and A(2B) receptors in cultured human and porcine coronary artery endothelial cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828458

Quantitative aspects of the insulin-receptor interaction in liver plasma membranes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828458

Troglitazone does not initiate hypertrophy but can sensitise cardiomyocytes to growth effects of serum

28 November 2018

1 reference

12 December 2020

Exercise-induced left ventricular dysfunction in young men with asymptomatic diabetes mellitus (diabetic cardiomyopathy)

1 reference

12 December 2020

Cardioprotection by remote ischemic preconditioning of the rat heart is mediated by extracellular vesicles

1 reference

12 December 2020

Myocyte death in streptozotocin-induced diabetes in rats in angiotensin II- dependent

1 reference

12 December 2020

Diabetic cardiomyopathy--fact or fiction?

1 reference

12 December 2020

Cardiac hypertrophy caused by peroxisome proliferator- activated receptor-gamma agonist treatment occurs independently of changes in myocardial insulin signaling

1 reference

12 December 2020

Myocardial cell death in human diabetes

1 reference

12 December 2020

A1 receptor deficiency causes increased insulin and glucagon secretion in mice

1 reference

12 December 2020

Heart Failure Prevalence, Incidence, and Mortality in the Elderly With Diabetes

1 reference

12 December 2020

Diabetic cardiomyopathy

1 reference

12 December 2020

The action of insulin on the distribution of galactose in eviscerated nephrectomized dogs

1 reference

12 December 2020

Absence of glucose transporter 4 diminishes electrical activity of mouse hearts during hypoxia

1 reference

12 December 2020

Relation among left ventricular mass, insulin resistance, and hemodynamic parameters in type 2 diabetes

1 reference

12 December 2020

Cardiomyocyte exosomes regulate glycolytic flux in endothelium by direct transfer of GLUT transporters and glycolytic enzymes

1 reference

12 December 2020

Improved blood glucose disposal and altered insulin secretion patterns in adenosine A(1) receptor knockout mice

1 reference

12 December 2020

Expression of adenosine receptors in cardiac fibroblasts as a function of insulin and glucose level

1 reference

12 December 2020