Gut barrier structure, mucosal immunity and intestinal microbiota in the pathogenesis and treatment of HIV infection (Q26748743)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073405 AND SRC:MED&resulttype=core&format=json

1 April 2020

1 reference

25 October 2022

Gut barrier structure, mucosal immunity and intestinal microbiota in the pathogenesis and treatment of HIV infection (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073405 AND SRC:MED&resulttype=core&format=json

human immunodeficiency virus infectious disease

1 April 2020

main subject

7 references

23 March 2019

20 June 2019

16 September 2019

7 October 2019

11 October 2019

19 October 2019

1 July 2020

1 reference

16 September 2019

human digestive system

1 reference

7 October 2019

1 reference

11 October 2019

Retroviridae infectious disease

1 reference

19 October 2019

1 reference

RNA virus infectious disease

1 reference

1 July 2020

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073405 AND SRC:MED&resulttype=core&format=json

1 April 2020

Giulia Marchetti

series ordinal

3

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073405 AND SRC:MED&resulttype=core&format=json

1 April 2020

2

Daniel C Douek

1 reference

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1 April 2020

language of work or name

English

0 references

publication date

11 April 2016

9 references

23 March 2019

20 June 2019

16 September 2019

7 October 2019

11 October 2019

19 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073405 AND SRC:MED&resulttype=core&format=json

1 April 2020

1 July 2020

25 October 2022

AIDS Research and Therapy

9 references

23 March 2019

20 June 2019

16 September 2019

7 October 2019

11 October 2019

19 October 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073405 AND SRC:MED&resulttype=core&format=json

1 April 2020

1 July 2020

25 October 2022

13

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073405 AND SRC:MED&resulttype=core&format=json

1 April 2020

issue

1

0 references

page(s)

19

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073405 AND SRC:MED&resulttype=core&format=json

Creative Commons Attribution 4.0 International

1 April 2020

copyright license

8 references

23 March 2019

20 June 2019

16 September 2019

7 October 2019

11 October 2019

19 October 2019

1 July 2020

on focus list of Wikimedia project

25 October 2022

copyright status

copyrighted

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ScienceSource

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cites work

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1 reference

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Microbial translocation is a cause of systemic immune activation in chronic HIV infection

7 April 2017

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CD4 T cell depletion during all stages of HIV disease occurs predominantly in the gastrointestinal tract

7 April 2017

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The gut microbiota and host health: a new clinical frontier

7 April 2017

1 reference

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IL-21 and probiotic therapy improve Th17 frequencies, microbial translocation, and microbiome in ARV-treated, SIV-infected macaques

7 April 2017

1 reference

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Maintenance of intestinal Th17 cells and reduced microbial translocation in SIV-infected rhesus macaques treated with interleukin (IL)-21

7 April 2017

1 reference

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Inflammatory and coagulation biomarkers and mortality in patients with HIV infection

7 April 2017

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Massive infection and loss of memory CD4 T cells in multiple tissues during acute SIV infection

7 April 2017

1 reference

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Impaired gut junctional complexes feature late-treated individuals with suboptimal CD4 T-cell recovery upon virologically suppressive combination antiretroviral therapy

7 April 2017

1 reference

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Gut-Resident Lactobacillus Abundance Associates with IDO1 Inhibition and Th17 Dynamics in SIV-Infected Macaques

28 September 2017

1 reference

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Interleukin-21 combined with ART reduces inflammation and viral reservoir in SIV-infected macaques

28 September 2017

1 reference

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Increased Tryptophan Catabolism Is Associated With Increased Frequency of CD161 Tc17/MAIT Cells and Lower CD4 T-Cell Count in HIV-1 Infected Patients on cART After 2 Years of Follow-Up

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Probiotics Reduce Inflammation in Antiretroviral Treated, HIV-Infected Individuals: Results of the "Probio-HIV" Clinical Trial

28 September 2017

1 reference

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Reduced Levels of D-dimer and Changes in Gut Microbiota Composition After Probiotic Intervention in HIV-Infected Individuals on Stable ART.

28 September 2017

1 reference

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The effect of timing of antiretroviral therapy on CD4 T-cell reconstitution in the intestine of HIV-infected patients

28 September 2017

1 reference

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Chloroquine and beyond: exploring anti-rheumatic drugs to reduce immune hyperactivation in HIV/AIDS.

28 September 2017

1 reference

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Impaired Th17 polarization of phenotypically naive CD4( ) T-cells during chronic HIV-1 infection and potential restoration with early ART

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

The Interplay Between Host Genetic Variation, Viral Replication, and Microbial Translocation in Untreated HIV-Infected Individuals

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

HIV-associated mucosal gene expression: region-specific alterations

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Dysbiotic bacteria translocate in progressive SIV infection.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

The immunologic effects of mesalamine in treated HIV-infected individuals with incomplete CD4 T cell recovery: a randomized crossover trial

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Initiation of ART during early acute HIV infection preserves mucosal Th17 function and reverses HIV-related immune activation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Effect of probiotics (Saccharomyces boulardii) on microbial translocation and inflammation in HIV-treated patients: a double-blind, randomized, placebo-controlled trial

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Altered metabolism of gut microbiota contributes to chronic immune activation in HIV-infected individuals.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Antiretroviral therapy in HIV-infected elite controllers: impact on gut immunology, microbial translocation, and biomarkers of serious non-AIDS conditions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Gut epithelial barrier and systemic inflammation during chronic HIV infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Reconstitution of intestinal CD4 and Th17 T cells in antiretroviral therapy suppressed HIV-infected subjects: implication for residual immune activation from the results of a clinical trial

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Rifaximin has a marginal impact on microbial translocation, T-cell activation and inflammation in HIV-positive immune non-responders to antiretroviral therapy - ACTG A5286.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Intestinal microbiota, microbial translocation, and systemic inflammation in chronic HIV infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Anti-retroviral therapy decreases but does not normalize indoleamine 2,3-dioxygenase activity in HIV-infected patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Progressive proximal-to-distal reduction in expression of the tight junction complex in colonic epithelium of virally-suppressed HIV individuals.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Sevelamer does not decrease lipopolysaccharide or soluble CD14 levels but decreases soluble tissue factor, low-density lipoprotein (LDL) cholesterol, and oxidized LDL cholesterol levels in individuals with untreated HIV infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Early microbial translocation blockade reduces SIV-mediated inflammation and viral replication

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Soluble markers of inflammation and coagulation but not T-cell activation predict non-AIDS-defining morbid events during suppressive antiretroviral treatment

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Gut epithelial barrier dysfunction and innate immune activation predict mortality in treated HIV infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

A compositional look at the human gastrointestinal microbiome and immune activation parameters in HIV infected subjects

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

The kynurenine pathway of tryptophan catabolism, CD4 T-cell recovery, and mortality among HIV-infected Ugandans initiating antiretroviral therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

HIV Infection is associated with compositional and functional shifts in the rectal mucosal microbiota

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

An altered intestinal mucosal microbiome in HIV-1 infection is associated with mucosal and systemic immune activation and endotoxemia.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Gut Lactobacillales are associated with higher CD4 and less microbial translocation during HIV infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Dysbiosis of the gut microbiota is associated with HIV disease progression and tryptophan catabolism

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

The Th17/Treg ratio, IL-1RA and sCD14 levels in primary HIV infection predict the T-cell activation set point in the absence of systemic microbial translocation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Probiotic/prebiotic supplementation of antiretrovirals improves gastrointestinal immunity in SIV-infected macaques.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Human immunodeficiency virus and the gastrointestinal immune system: does highly active antiretroviral therapy restore gut immunity?

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Loss of mucosal CD103 DCs and IL-17 and IL-22 lymphocytes is associated with mucosal damage in SIV infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

The colocalization potential of HIV-specific CD8 and CD4 T-cells is mediated by integrin β7 but not CCR6 and regulated by retinoic acid

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Specific prebiotics modulate gut microbiota and immune activation in HAART-naive HIV-infected adults: results of the "COPA" pilot randomized trial

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Evidence for polymicrobic flora translocating in peripheral blood of HIV-infected patients with poor immune response to antiretroviral therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Molecular Characterization of Stool Microbiota in HIV-Infected Subjects by Panbacterial and Order-Level 16S Ribosomal DNA (rDNA) Quantification and Correlations With Immune Activation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Epithelial adhesion molecules can inhibit HIV-1-specific CD8⁺ T-cell functions

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Plasma levels of soluble CD14 independently predict mortality in HIV infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Damaged intestinal epithelial integrity linked to microbial translocation in pathogenic simian immunodeficiency virus infections

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

A role for syndecan-1 and claudin-2 in microbial translocation during HIV-1 infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Tryptophan catabolism by indoleamine 2,3-dioxygenase 1 alters the balance of TH17 to regulatory T cells in HIV disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Exposure to HIV-1 directly impairs mucosal epithelial barrier integrity allowing microbial translocation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Peripheral blood CCR4 CCR6 and CXCR3 CCR6 CD4 T cells are highly permissive to HIV-1 infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Plasma levels of bacterial DNA correlate with immune activation and the magnitude of immune restoration in persons with antiretroviral-treated HIV infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

IL-22 ameliorates intestinal inflammation in a mouse model of ulcerative colitis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Early impairment of gut function and gut flora supporting a role for alteration of gastrointestinal mucosa in human immunodeficiency virus pathogenesis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Comparative analysis of T-cell turnover and homeostatic parameters in HIV-infected patients with discordant immune-virological responses to HAART.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

T Cell Activation Is Associated with Lower CD4 T Cell Gains in Human Immunodeficiency Virus–Infected Patients with Sustained Viral Suppression during Antiretroviral Therapy

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

HIV preferentially infects HIV-specific CD4 T cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Association of microbial translocation biomarkers with clinical outcome in controllers HIV-infected patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Immunosuppressive Tryptophan Catabolism and Gut Mucosal Dysfunction Following Early HIV Infection

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Loss of Th22 cells is associated with increased immune activation and IDO-1 activity in HIV-1 infection

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Early initiation of combined antiretroviral therapy preserves immune function in the gut of HIV-infected patients.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Shorter survival in advanced human immunodeficiency virus type 1 infection is more closely associated with T lymphocyte activation than with plasma virus burden or virus chemokine coreceptor usage.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4828806

Microbial translocation predicts disease progression of HIV-infected antiretroviral-naive patients with high CD4 cell count

31 May 2018

1 reference

https://api.crossref.org/works/10.1186/S12981-016-0103-1

IL-17, produced by lymphocytes and neutrophils, is necessary for lipopolysaccharide-induced airway neutrophilia: IL-15 as a possible trigger

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S12981-016-0103-1

Mucosal Th17 cell function is altered during HIV infection and is an independent predictor of systemic immune activation

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S12981-016-0103-1

Memory CCR6 CD4 T cells are preferential targets for productive HIV type 1 infection regardless of their expression of integrin β7.

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S12981-016-0103-1

Immune activation set point during early HIV infection predicts subsequent CD4 T-cell changes independent of viral load

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S12981-016-0103-1

The Immunomodulatory Nutritional Intervention NR100157 Reduced CD4 T-Cell Decline and Immune Activation: A 1-Year Multicenter Randomized Controlled Double-Blind Trial in HIV-Infected Persons Not Receiving Antiretroviral Therapy (The BITE Study)

21 January 2018

1 reference

https://api.crossref.org/works/10.1186/S12981-016-0103-1

Elevated relative fluorescence intensity of CD38 antigen expression on CD8 T cells is a marker of poor prognosis in HIV infection: results of 6 years of follow-up

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27073405

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Microbial translocation is associated with sustained failure in CD4 T-cell reconstitution in HIV-infected patients on long-term highly active antiretroviral therapy

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27073405

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Impaired gut junctional complexes feature late-treated individuals with suboptimal CD4 T-cell recovery upon virologically-suppressive cART.

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/27073405

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1186/S12981-016-0103-1

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073405 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

1 April 2020

1044618152

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27073405 AND SRC:MED&resulttype=core&format=json

1 April 2020

PubMed publication ID

27073405

2 references