Breaking Free of Control: How Conventional T Cells Overcome Regulatory T Cell Suppression (Q26744624)

20 June 2017

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title

Breaking Free of Control: How Conventional T Cells Overcome Regulatory T Cell Suppression (English)

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20 June 2017

Ulrike M Lorenz

2

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author name string

Emily R Mercadante

series ordinal

1

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20 June 2017

language of work or name

English

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publication date

18 May 2016

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20 June 2017

published in

Frontiers in Immunology

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20 June 2017

volume

7

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20 June 2017

page(s)

193

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A THEMIS:SHP1 complex promotes T-cell survival

20 June 2017

cites work

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Interferon-Beta Therapy of Multiple Sclerosis Patients Improves the Responsiveness of T Cells for Immune Suppression by Regulatory T Cells.

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Adoptive T Regulatory Cell Therapy for Tolerance Induction

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28 September 2017

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Cutting edge: Genetic variation in TLR1 is associated with Pam3CSK4-induced effector T cell resistance to regulatory T cell suppression

28 September 2017

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Gr-1⁺CD11b⁺ immature myeloid cells (IMC) promote resistance of pro-inflammatory T cells to suppression by regulatory T cells in atherosclerotic Apo E- deficient mice

28 September 2017

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Regulation of nasal airway homeostasis and inflammation in mice by SHP-1 and Th2/Th1 signaling pathways

28 September 2017

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Signaling specificity in the Akt pathway in biology and disease

28 September 2017

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Molecular pathways: interleukin-15 signaling in health and in cancer

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Perspectives of the relationship between IL-7 and autoimmune diseases.

28 September 2017

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28 September 2017

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Shp1 regulates T cell homeostasis by limiting IL-4 signals

28 September 2017

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Regulation of PI-3-Kinase and Akt Signaling in T Lymphocytes and Other Cells by TNFR Family Molecules

28 September 2017

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28 September 2017

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Distinct roles for neutrophils and dendritic cells in inflammation and autoimmunity in motheaten mice

28 September 2017

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SHP-1 phosphatase activity counteracts increased T cell receptor affinity

28 September 2017

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28 September 2017

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28 September 2017

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OX40 signaling favors the induction of T(H)9 cells and airway inflammation

28 September 2017

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Abrogation of SRC homology region 2 domain-containing phosphatase 1 in tumor-specific T cells improves efficacy of adoptive immunotherapy by enhancing the effector function and accumulation of short-lived effector T cells in vivo

28 September 2017

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Mechanisms of T(reg) Suppression: Still a Long Way to Go.

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28 September 2017

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The role of interleukin-2 during homeostasis and activation of the immune system

28 September 2017

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28 September 2017

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28 September 2017

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H2 Control of Natural T Regulatory Cell Frequency in the Lymph Node Correlates with Susceptibility to Day 3 Thymectomy-Induced Autoimmune Disease

28 September 2017

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Mechanisms of impaired regulation by CD4( )CD25( )FOXP3( ) regulatory T cells in human autoimmune diseases

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The protein tyrosine phosphatase SHP-1 modulates the suppressive activity of regulatory T cells

28 September 2017

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28 September 2017

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T cells expressing constitutively active Akt resist multiple tumor-associated inhibitory mechanisms.

28 September 2017

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Program death-1 signaling and regulatory T cells collaborate to resist the function of adoptively transferred cytotoxic T lymphocytes in advanced acute myeloid leukemia.

28 September 2017

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Expression of costimulatory TNFR2 induces resistance of CD4 FoxP3- conventional T cells to suppression by CD4 FoxP3 regulatory T cells.

28 September 2017

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Regulatory T cells in tumor immunity

28 September 2017

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OX40-OX40 ligand interaction in T-cell-mediated immunity and immunopathology.

28 September 2017

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Cbl-b in T-cell activation

28 September 2017

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OX40 is required for regulatory T cell-mediated control of colitis

28 September 2017

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The IL-1 family: regulators of immunity

28 September 2017

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Anti-TNF biologic agents: still the therapy of choice for rheumatoid arthritis

28 September 2017

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Engagement of TLR2 does not reverse the suppressor function of mouse regulatory T cells, but promotes their survival

28 September 2017

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PD1 blockade reverses the suppression of melanoma antigen-specific CTL by CD4 CD25(Hi) regulatory T cells

28 September 2017

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IL-6 signaling in psoriasis prevents immune suppression by regulatory T cells

28 September 2017

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New insights into the regulation of T cells by gamma(c) family cytokines

28 September 2017

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STAT6 activation confers upon T helper cells resistance to suppression by regulatory T cells.

28 September 2017

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Immune regulation by 4-1BB and 4-1BBL: complexities and challenges

28 September 2017

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SHP-1 and SHP-2 in T cells: two phosphatases functioning at many levels

28 September 2017

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Mechanisms of interleukin-1beta release

28 September 2017

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The interleukin-1 receptor/Toll-like receptor superfamily: 10 years of progress.

28 September 2017

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The defect in T-cell regulation in NOD mice is an effect on the T-cell effectors

28 September 2017

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The effector T cells of diabetic subjects are resistant to regulation via CD4 FOXP3 regulatory T cells

28 September 2017

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A critical role for direct TLR2-MyD88 signaling in CD8 T-cell clonal expansion and memory formation following vaccinia viral infection

28 September 2017

1 reference

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Intracellular signals of T cell costimulation

28 September 2017

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Foxp3 natural regulatory T cells preferentially form aggregates on dendritic cells in vitro and actively inhibit their maturation

28 September 2017

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Cutting edge: expression of TNFR2 defines a maximally suppressive subset of mouse CD4 CD25 FoxP3 T regulatory cells: applicability to tumor-infiltrating T regulatory cells.

28 September 2017

1 reference

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CD137 costimulation of CD8 T cells confers resistance to suppression by virus-induced regulatory T cells

28 September 2017

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OX40 triggering blocks suppression by regulatory T cells and facilitates tumor rejection

28 September 2017

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Allograft rejection mediated by memory T cells is resistant to regulation

28 September 2017

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Regulatory T cells - a brief history and perspective

28 September 2017

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Antigen-specific tolerance strategies for the prevention and treatment of autoimmune disease

28 September 2017

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OX40 costimulation turns off Foxp3 Tregs.

28 September 2017

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Spontaneous tumor rejection by cbl-b-deficient CD8 T cells

28 September 2017

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Myelin-specific regulatory T cells accumulate in the CNS but fail to control autoimmune inflammation.

28 September 2017

1 reference

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Ablation of Cbl-b provides protection against transplanted and spontaneous tumors

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

'Vive la Résistance!'--the PI3K-Akt pathway can determine target sensitivity to regulatory T cell suppression

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

CpG DNA inhibits CD4 CD25 Treg suppression through direct MyD88-dependent costimulation of effector CD4 T cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Selective depletion of Foxp3 regulatory T cells induces a scurfy-like disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

The adaptor molecule MyD88 activates PI-3 kinase signaling in CD4 T cells and enables CpG oligodeoxynucleotide-mediated costimulation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Toll-like receptors on regulatory T cells: expanding immune regulation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Toll-like receptor 2 signaling modulates the functions of CD4 CD25 regulatory T cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

28 September 2017

FOXP3: of mice and men.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

TNF downmodulates the function of human CD4 CD25hi T-regulatory cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Toll-like receptor 2 controls expansion and function of regulatory T cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

IL-2 administration increases CD4 CD25(hi) Foxp3 regulatory T cells in cancer patients

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Sodium stibogluconate interacts with IL-2 in anti-Renca tumor action via a T cell-dependent mechanism in connection with induction of tumor-infiltrating macrophages

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Developmental regulation of Foxp3 expression during ontogeny.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Coexpression of CD25 and CD27 identifies FoxP3 regulatory T cells in inflamed synovia

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Costimulation by CD137/4-1BB inhibits T cell apoptosis and induces Bcl-xL and c-FLIP(short) via phosphatidylinositol 3-kinase and AKT/protein kinase B.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Localization of Src homology 2 domain-containing phosphatase 1 (SHP-1) to lipid rafts in T lymphocytes: functional implications and a role for the SHP-1 carboxyl terminus

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

PI3K/AKT signaling and systemic autoimmunity

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Interleukin-15: a new cytokine target for the treatment of inflammatory diseases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Phosphoinositide 3-kinase and its targets in B-cell and T-cell signaling

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

TRAF6, a molecular bridge spanning adaptive immunity, innate immunity and osteoimmunology.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Regulatory T cells selectively express toll-like receptors and are activated by lipopolysaccharide

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

CD4( )CD25( ) immunoregulatory T cells: gene expression analysis reveals a functional role for the glucocorticoid-induced TNF receptor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Stimulation of CD25( )CD4( ) regulatory T cells through GITR breaks immunological self-tolerance

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Stat6 and IRS-2 cooperate in interleukin 4 (IL-4)-induced proliferation and differentiation but are dispensable for IL-4-dependent rescue from apoptosis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Proteolysis-independent regulation of PI3K by Cbl-b-mediated ubiquitination in T cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Phosphatidylinositol 3-kinase potentiates, but does not trigger, T cell proliferation mediated by the IL-2 receptor

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Tyrosine phosphorylation of p85 relieves its inhibitory activity on phosphatidylinositol 3-kinase

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Strong and selective glomerular localization of CD134 ligand and TNF receptor-1 in proliferative lupus nephritis

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Cbl-b regulates the CD28 dependence of T-cell activation.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Expression of lymphocyte-endothelial receptor-ligand pairs, alpha4beta7/MAdCAM-1 and OX40/OX40 ligand in the colon and jejunum of patients with inflammatory bowel disease

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Interleukin-7: physiological roles and mechanisms of action

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

The contribution of direct TLR signaling to T cell responses.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

NFATc2 and NFATc3 transcription factors play a crucial role in suppression of CD4 T lymphocytes by CD4 CD25 regulatory T cells

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Interleukin-2 receptor regulates activation of phosphatidylinositol 3-kinase

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Autoimmune diabetes onset results from qualitative rather than quantitative age-dependent changes in pathogenic T-cells.

31 May 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Release from regulatory T cell-mediated suppression during the onset of tissue-specific autoimmunity is associated with elevated IL-21.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Functional human regulatory T cells fail to control autoimmune inflammation due to PKB/c-akt hyperactivation in effector cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Anti-tumor necrosis factor α targets protein kinase B/c-Akt-induced resistance of effector cells to suppression in juvenile idiopathic arthritis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Reduced CD4 ,CD25- T cell sensitivity to the suppressive function of CD4 ,CD25high,CD127 -/low regulatory T cells in patients with active systemic lupus erythematosus

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Quantitative and qualitative normal regulatory T cells are not capable of inducing suppression in SLE patients due to T-cell resistance.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

In active relapsing-remitting multiple sclerosis, effector T cell resistance to adaptive T(regs) involves IL-6-mediated signaling

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Impaired control of effector T cells by regulatory T cells: a clue to loss of oral tolerance and autoimmunity in celiac disease?

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Smad7 controls resistance of colitogenic T cells to regulatory T cell-mediated suppression

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Immunologic self-tolerance maintained by CD25 CD4 naturally anergic and suppressive T cells: induction of autoimmune disease by breaking their anergic/suppressive state

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

IL-15 renders conventional lymphocytes resistant to suppressive functions of regulatory T cells through activation of the phosphatidylinositol 3-kinase pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

IL-1 beta breaks tolerance through expansion of CD25 effector T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

TLR2 stimulation drives human naive and effector regulatory T cells into a Th17-like phenotype with reduced suppressive function

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Engagement of glucocorticoid-induced TNFR family-related receptor on effector T cells by its ligand mediates resistance to suppression by CD4 CD25 T cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

4-1BB-dependent inhibition of immunosuppression by activated CD4 CD25 T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Distinct roles for the OX40-OX40 ligand interaction in regulatory and nonregulatory T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Regulatory T cell-resistant CD8 T cells induced by glucocorticoid-induced tumor necrosis factor receptor signaling.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Triggering of OX40 (CD134) on CD4( )CD25 T cells blocks their inhibitory activity: a novel regulatory role for OX40 and its comparison with GITR.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

CD134L expression on dendritic cells in the mesenteric lymph nodes drives colitis in T cell-restored SCID mice.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Interaction of TNF with TNF receptor type 2 promotes expansion and function of mouse CD4 CD25 T regulatory cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

PKC-theta modulates the strength of T cell responses by targeting Cbl-b for ubiquitination and degradation

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Resistance to CD4 CD25 regulatory T cells and TGF-beta in Cbl-b-/- mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

TCR ligand discrimination is enforced by competing ERK positive and SHP-1 negative feedback pathways

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Addition of the CD28 signaling domain to chimeric T-cell receptors enhances chimeric T-cell resistance to T regulatory cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Function of CD4 ,CD25 Treg cells in MRL/lpr mice is compromised by intrinsic defects in antigen-presenting cells and effector T cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Human CD4 T Cells Express TLR5 and Its Ligand Flagellin Enhances the Suppressive Capacity and Expression of FOXP3 in CD4 CD25 T Regulatory Cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

Enhanced activity of Akt in Teff cells from children with lupus nephritis is associated with reduced induction of tumor necrosis factor receptor-associated factor 6 and increased OX40 expression

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Cutting edge: Cbl-b: one of the key molecules tuning CD28- and CTLA-4-mediated T cell costimulation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Requirement for CD28 co-stimulation is lower in SHP-1-deficient T cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

CD4 CD25high regulatory cells in human peripheral blood

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4870238

Negative regulation of lymphocyte activation and autoimmunity by the molecular adaptor Cbl-b

28 November 2018

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

MRL/Mp CD4 ,CD25- T cells show reduced sensitivity to suppression by CD4 ,CD25 regulatory T cells in vitro: a novel defect of T cell regulation in systemic lupus erythematosus

21 January 2018

1 reference

12 December 2020

Self-Sustained Resistance to Suppression of CD8 Teff Cells at the Site of Autoimmune Inflammation Can Be Reversed by Tumor Necrosis Factor and Interferon-γ Blockade

1 reference

12 December 2020

1 reference

12 December 2020

Cbl-b(-/-) T cells demonstrate in vivo resistance to regulatory T cells but a context-dependent resistance to TGF-beta

1 reference

12 December 2020

Pivotal roles of CD4 effector T cells in mediating agonistic anti-GITR mAb-induced-immune activation and tumor immunity in CT26 tumors

1 reference

12 December 2020

IL-21 Counteracts the Regulatory T Cell-Mediated Suppression of Human CD4 T Lymphocytes

1 reference

12 December 2020

Involvement of the programmed death-1/programmed death-1 ligand pathway in CD4 CD25 regulatory T-cell activity to suppress alloimmune responses

1 reference

12 December 2020

The inflamed central nervous system drives the activation and rapid proliferation of Foxp3 regulatory T cells

1 reference

12 December 2020

Ex vivo expansion of CD4 CD25 FoxP3 T regulatory cells based on synergy between IL-2 and 4-1BB signaling

1 reference

12 December 2020

Toll pathway-dependent blockade of CD4 CD25 T cell-mediated suppression by dendritic cells

1 reference

12 December 2020

Differential but direct abolishment of human regulatory T cell suppressive capacity by various TLR2 ligands

1 reference

12 December 2020

The expression of OX40 in immunologically mediated diseases of the gastrointestinal tract (celiac disease, Crohn's disease, ulcerative colitis)

1 reference

12 December 2020

CD25 CD4 T cells regulate the expansion of peripheral CD4 T cells through the production of IL-10

1 reference

12 December 2020

TRAF6 is a T cell-intrinsic negative regulator required for the maintenance of immune homeostasis

1 reference

12 December 2020

TRAIL Is Associated with Impaired Regulation of CD4 CD25− T Cells by Regulatory T Cells in Patients with Rheumatoid Arthritis

1 reference

12 December 2020

Cutting edge: IL-4-induced protection of CD4 CD25- Th cells from CD4 CD25 regulatory T cell-mediated suppression

1 reference

12 December 2020

T lymphocytes in the synovial fluid of patients with active rheumatoid arthritis display CD134-OX40 surface antigen

1 reference

12 December 2020

Increased resistance to CD4 CD25hi regulatory T cell-mediated suppression in patients with type 1 diabetes

1 reference

12 December 2020

Impaired suppression of synovial fluid CD4 CD25− T cells from patients with juvenile idiopathic arthritis by CD4 CD25 Treg cells

1 reference

12 December 2020

Early kinetic window of target T cell susceptibility to CD25 regulatory T cell activity

1 reference

12 December 2020

IL-21 promotes T lymphocyte survival by activating the phosphatidylinositol-3 kinase signaling cascade

1 reference

12 December 2020

High antigen dose and activated dendritic cells enable Th cells to escape regulatory T cell-mediated suppression in vitro

1 reference

12 December 2020

The inflammatory milieu in the rheumatic joint reduces regulatory T‐cell function

1 reference

12 December 2020

Jagged2-signaling promotes IL-6-dependent transplant rejection

1 reference

12 December 2020

Proinflammatory mediator–induced reversal of CD4 ,CD25 regulatory T cell–mediated suppression in rheumatoid arthritis

1 reference

12 December 2020

Motheaten and viable motheaten mice have mutations in the haematopoietic cell phosphatase gene

1 reference

12 December 2020

Correlation of peripheral blood OX40 (CD134 ) T cells with chronic graft-versus-host disease in patients who underwent allogeneic hematopoietic stem cell transplantation

1 reference

12 December 2020

Plasmin immunization preferentially induces potentially prothrombotic IgG anticardiolipin antibodies in MRL/MpJ mice.

1 reference

https://api.crossref.org/works/10.3389/FIMMU.2016.00193

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.3389/FIMMU.2016.00193

1 reference

OpenCitations bibliographic resource ID

20 June 2017

1544942

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1544942

1 reference