Role of EPAC in cAMP-Mediated Actions in Adrenocortical Cells (Q26744605)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27379015 AND SRC:MED&resulttype=core&format=json

17 March 2020

review article

1 reference

title

Role of EPAC in cAMP-Mediated Actions in Adrenocortical Cells (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27379015 AND SRC:MED&resulttype=core&format=json

17 March 2020

1

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17 March 2020

author name string

Reidun Aesoy

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27379015 AND SRC:MED&resulttype=core&format=json

17 March 2020

Marit Bakke

series ordinal

3

1 reference

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17 March 2020

language of work or name

English

0 references

publication date

13 June 2016

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27379015 AND SRC:MED&resulttype=core&format=json

Frontiers in Endocrinology

17 March 2020

published in

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27379015 AND SRC:MED&resulttype=core&format=json

17 March 2020

volume

7

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17 March 2020

page(s)

63

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60 YEARS OF POMC: Adrenal and extra-adrenal functions of ACTH

17 March 2020

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1 reference

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cAMP sensor Epac as a determinant of ATP-sensitive potassium channel activity in human pancreatic beta cells and rat INS-1 cells

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Metabolites of an Epac-selective cAMP analog induce cortisol synthesis by adrenocortical cells through a cAMP-independent pathway

7 April 2017

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7 April 2017

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7 April 2017

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cAMP-GEFII is a direct target of cAMP in regulated exocytosis

7 April 2017

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7 April 2017

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Epac2 induces synapse remodeling and depression and its disease-associated forms alter spines

7 April 2017

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The pleiotropic role of exchange protein directly activated by cAMP 1 (EPAC1) in cancer: implications for therapeutic intervention

7 April 2017

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Structure and functional roles of Epac2 (Rapgef4).

28 September 2017

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The future of EPAC-targeted therapies: agonism versus antagonism

28 September 2017

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Pharmacological inhibition and genetic knockdown of exchange protein directly activated by cAMP 1 reduce pancreatic cancer metastasis in vivo

28 September 2017

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Epac1-dependent phospholamban phosphorylation mediates the cardiac response to stresses

28 September 2017

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Cyclic AMP sensor EPAC proteins and energy homeostasis

28 September 2017

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DNA methylation of alternative promoters directs tissue specific expression of Epac2 isoforms

28 September 2017

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Pancreatic β-cell response to increased metabolic demand and to pharmacologic secretagogues requires EPAC2A

28 September 2017

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Epac2 mediates cardiac β1-adrenergic-dependent sarcoplasmic reticulum Ca2 leak and arrhythmia.

28 September 2017

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Organelle plasticity and interactions in cholesterol transport and steroid biosynthesis.

28 September 2017

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Regulation of adrenocortical steroid hormone production by RhoA-diaphanous 1 signaling and the cytoskeleton

28 September 2017

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Activation of a cyclic amp-guanine exchange factor in hepatocytes decreases nitric oxide synthase expression

28 September 2017

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Social, communication, and cortical structural impairments in Epac2-deficient mice

28 September 2017

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EPAC null mutation impairs learning and social interactions via aberrant regulation of miR-124 and Zif268 translation

28 September 2017

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cAMP regulates DEP domain-mediated binding of the guanine nucleotide exchange factor Epac1 to phosphatidic acid at the plasma membrane

28 September 2017

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28 September 2017

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28 September 2017

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Bile acid stimulates hepatocyte polarization through a cAMP-Epac-MEK-LKB1-AMPK pathway

28 September 2017

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28 September 2017

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Ion channels and signaling in the pituitary gland

28 September 2017

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Exchange protein directly activated by cyclic AMP increases melanoma cell migration by a Ca2 -dependent mechanism

28 September 2017

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Functional roles of protein kinase A (PKA) and exchange protein directly activated by 3',5'-cyclic adenosine 5'-monophosphate (cAMP) 2 (EPAC2) in cAMP-mediated actions in adrenocortical cells

28 September 2017

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The role of Epac proteins, novel cAMP mediators, in the regulation of immune, lung and neuronal function

28 September 2017

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Role of CRF receptor signaling in stress vulnerability, anxiety, and depression.

28 September 2017

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The cAMP sensor Epac2 is a direct target of antidiabetic sulfonylurea drugs

28 September 2017

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Corticotropin releasing factor-induced ERK phosphorylation in AtT20 cells occurs via a cAMP-dependent mechanism requiring EPAC2.

28 September 2017

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Regulatory mechanisms underlying corticotropin-releasing factor gene expression in the hypothalamus

28 September 2017

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Critical role of the N-terminal cyclic AMP-binding domain of Epac2 in its subcellular localization and function

28 September 2017

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Molecular mechanisms of corticotropin-releasing factor receptor-induced calcium signaling

28 September 2017

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Epac mediates PACAP-dependent long-term depression in the hippocampus

28 September 2017

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Ras is required for the cyclic AMP-dependent activation of Rap1 via Epac2

28 September 2017

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Regulation of steroid hormone biosynthesis by the cytoskeleton

28 September 2017

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ACTH inhibits bTREK-1 K channels through multiple cAMP-dependent signaling pathways

28 September 2017

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Cyclic AMP (cAMP)-mediated stimulation of adipocyte differentiation requires the synergistic action of Epac- and cAMP-dependent protein kinase-dependent processes

28 September 2017

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28 September 2017

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Epac, in synergy with cAMP-dependent protein kinase (PKA), is required for cAMP-mediated mitogenesis

28 September 2017

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Essential role of Epac2/Rap1 signaling in regulation of insulin granule dynamics by cAMP.

28 September 2017

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Developmental changes in gene expression of Epac and its upregulation in myocardial hypertrophy.

28 September 2017

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Global profiles of gene expression induced by adrenocorticotropin in Y1 mouse adrenal cells

28 September 2017

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Structure of the cyclic-AMP-responsive exchange factor Epac2 in its auto-inhibited state

28 September 2017

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Regulation of sodium-proton exchanger isoform 3 (NHE3) by PKA and exchange protein directly activated by cAMP (EPAC).

28 September 2017

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Pituitary adenylate cyclase-activating polypeptide (PACAP) mimics neuroendocrine and behavioral manifestations of stress: Evidence for PKA-mediated expression of the corticotropin-releasing hormone (CRH) gene

28 September 2017

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Cyclic AMP potentiates vascular endothelial cadherin-mediated cell-cell contact to enhance endothelial barrier function through an Epac-Rap1 signaling pathway

28 September 2017

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The orphan nuclear receptor NGFIB regulates transcription of 3beta-hydroxysteroid dehydrogenase. implications for the control of adrenal functional zonation

28 September 2017

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Among circulating hematopoietic cells, B-CLL uniquely expresses functional EPAC1, but EPAC1-mediated Rap1 activation does not account for PDE4 inhibitor-induced apoptosis.

28 September 2017

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Screening of nine candidate genes for autism on chromosome 2q reveals rare nonsynonymous variants in the cAMP-GEFII gene

28 September 2017

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ACTH modulation of transcription factors responsible for steroid hydroxylase gene expression in the adrenal cortex

28 September 2017

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Mechanism of action of ACTH: beyond cAMP.

28 September 2017

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Cyclic AMP induces integrin-mediated cell adhesion through Epac and Rap1 upon stimulation of the beta 2-adrenergic receptor

28 September 2017

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Characterization of the gene EPAC2: structure, chromosomal localization, tissue expression, and identification of the liver-specific isoform

28 September 2017

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Post-translational regulation of steroidogenic acute regulatory protein by cAMP-dependent protein kinase A.

28 September 2017

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The role of the StAR protein in steroidogenesis: challenges for the future

28 September 2017

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Multiple orphan nuclear receptors converge to regulate rat P450c17 gene transcription: novel mechanisms for orphan nuclear receptor action

28 September 2017

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The orphan nuclear receptor NGFI-B regulates expression of the gene encoding steroid 21-hydroxylase.

28 September 2017

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Proopiomelanocortin processing in the pituitary, central nervous system, and peripheral tissues

28 September 2017

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Light and electron microscopic immunohistochemistry of the localization of adrenal steroidogenic enzymes

28 September 2017

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cAMP-dependent signaling as a core component of the mammalian circadian pacemaker

28 September 2017

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Epac: a new cAMP target and new avenues in cAMP research

31 May 2018

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https://api.crossref.org/works/10.3389/FENDO.2016.00063

PKA and Epac1 regulate endothelial integrity and migration through parallel and independent pathways

21 January 2018

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Activation of cAMP-guanine exchange factor confers PKA-independent protection from hepatocyte apoptosis

21 January 2018

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cAMP-binding protein Epac induces cardiomyocyte hypertrophy.

21 January 2018

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https://api.crossref.org/works/10.3389/FENDO.2016.00063

Exchange protein activated by cAMP 1 (Epac1)-deficient mice develop β-cell dysfunction and metabolic syndrome

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FENDO.2016.00063

Exchange protein activated by cyclic AMP 2 (Epac2) plays a specific and time-limited role in memory retrieval

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FENDO.2016.00063

The phenotypic differentiation of locus ceruleus noradrenergic neurons mediated by brain-derived neurotrophic factor is enhanced by corticotropin releasing factor through the activation of a cAMP-dependent signaling pathway

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FENDO.2016.00063

Adrenocorticotropin/cyclic adenosine 3',5'-monophosphate-mediated transcription of the human CYP17 gene in the adrenal cortex is dependent on phosphatase activity

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FENDO.2016.00063

Regulation of aldosterone production from zona glomerulosa cells by ANG II and cAMP: evidence for PKA-independent activation of CaMK by cAMP.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FENDO.2016.00063

Activation and induction of NUR77/NURR1 in corticotrophs by CRH/cAMP: involvement of calcium, protein kinase A, and MAPK pathways

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4904129

Molecular determinants and feedback circuits regulating type 2 CRH receptor signal integration

28 November 2018

1 reference

12 December 2020

The cyclic AMP-Epac1-Rap1 pathway is dissociated from regulation of effector functions in monocytes but acquires immunoregulatory function in mature macrophages

1 reference

12 December 2020

cAMP-Epac2-mediated activation of Rap1 in developing male germ cells: RA-RhoGAP as a possible direct down-stream effector

1 reference

12 December 2020

Activation of cAMP-dependent protein kinase increases the protein level of steroidogenic factor-1

1 reference

12 December 2020

Identifiers

DOI

10.3389/FENDO.2016.00063

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27379015 AND SRC:MED&resulttype=core&format=json

17 March 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:27379015 AND SRC:MED&resulttype=core&format=json

17 March 2020

PubMed publication ID

27379015

2 references