Purinergic Signaling in Gut Inflammation: The Role of Connexins and Pannexins (Q26738433)

Frontiers in Neuroscience

Europe PubMed Central

title

Purinergic Signaling in Gut Inflammation: The Role of Connexins and Pannexins (English)

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Erica F Diezmos

1

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Paul P Bertrand

series ordinal

2

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Lu Liu

series ordinal

3

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language of work or name

English

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publication date

2016

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published in

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volume

10

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page(s)

311

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cites work

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28 September 2017

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Pannexin-1 hemichannel-mediated ATP release together with P2X1 and P2X4 receptors regulate T-cell activation at the immune synapse

28 September 2017

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28 September 2017

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From the Cover: CD39 deletion exacerbates experimental murine colitis and human polymorphisms increase susceptibility to inflammatory bowel disease

28 September 2017

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28 September 2017

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Glycosylation regulates pannexin intermixing and cellular localization

28 September 2017

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28 September 2017

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Connexin 43 hemichannel opening associated with Prostaglandin E(2) release is adaptively regulated by mechanical stimulation

28 September 2017

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28 September 2017

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28 September 2017

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New bioinformatics approach to analyze gene expressions and signaling pathways reveals unique purine gene dysregulation profiles that distinguish between CD and UC.

28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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28 September 2017

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Mechanical strain opens connexin 43 hemichannels in osteocytes: a novel mechanism for the release of prostaglandin

28 September 2017

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28 September 2017

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Gap junctions and the connexin protein family

28 September 2017

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28 September 2017

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Gap junctions in gastrointestinal muscle contain multiple connexins

28 September 2017

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P2 purinergic receptors: modulation of cell function and therapeutic potential

28 September 2017

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Immunolocalization of the gap junction protein Connexin43 in the interstitial cells of Cajal in the normal and Hirschsprung's disease bowel

28 September 2017

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Role of cytokines in the pathogenesis of inflammatory bowel disease

28 September 2017

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Adhesion and cytosolic dye transfer between macrophages and intestinal epithelial cells.

28 September 2017

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Role of connexin-43 hemichannels in the pathogenesis of Yersinia enterocolitica

28 September 2017

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Heightened Expression of CD39 by Regulatory T Lymphocytes Is Associated with Therapeutic Remission in Inflammatory Bowel Disease.

28 September 2017

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31 May 2018

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Astrocytes inhibit nitric oxide-dependent Ca(2 ) dynamics in activated microglia: involvement of ATP released via pannexin 1 channels.

31 May 2018

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Functional outcome of pannexin-deficient mice after cerebral ischemia

31 May 2018

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The P2X7 receptor and Pannexin-1 are both required for the promotion of multinucleated macrophages by the inflammatory cytokine GM-CSF.

31 May 2018

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31 May 2018

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Pannexin 1 contributes to ATP release in airway epithelia.

31 May 2018

1 reference

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Intracellular calcium changes trigger connexin 32 hemichannel opening

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925662

The distribution of P2X5 purinergic receptors in the enteric nervous system of mouse

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925662

Inflammatory bowel disease: etiology and pathogenesis

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925662

Disparate CD4 lamina propria (LP) lymphokine secretion profiles in inflammatory bowel disease. Crohn's disease LP cells manifest increased secretion of IFN-gamma, whereas ulcerative colitis LP cells manifest increased secretion of IL-5.

31 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=4925662

Role of transient receptor potential and pannexin channels in cigarette smoke-triggered ATP release in the lung

31 May 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

The distribution of purine P2X(2) receptors in the guinea-pig enteric nervous system

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Ca(2 ) regulation of connexin 43 hemichannels in C6 glioma and glial cells

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Expression and localization of pannexin-1 hemichannels in human colon in health and disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Pannexin-2 is expressed in the human colon with extensive localization in the enteric nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Ablation of connexin43 in smooth muscle cells of the mouse intestine: functional insights into physiology and morphology.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Aberrant expression of connexin 26 is associated with lung metastasis of colorectal cancer.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Gap junction hemichannels contribute to the generation of diarrhoea during infectious enteric disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

ADOA3R as a therapeutic target in experimental colitis: proof by validated high-density oligonucleotide microarray analysis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Peculiar antibody reactivity to human connexin 37 and its microbial mimics in patients with Crohn's disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Activation of pannexin 1 channels by ATP through P2Y receptors and by cytoplasmic calcium

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Sympathetic vasoconstrictor regulation of mouse colonic submucosal arterioles is altered in experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Intracellular calcium regulation of connexin43.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Possible role of pannexin 1/P2x7 purinoceptor in neuroprotective mechanism of ischemic postconditioning in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Prophylactic systemic P2X7 receptor blockade prevents experimental colitis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

ATP participates in three excitatory postsynaptic potentials in the submucous plexus of the guinea pig ileum.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Connexin 26-mediated gap junctional intercellular communication suppresses paracellular permeability of human intestinal epithelial cell monolayers

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Connexin 43 mimetic peptides reduce swelling, astrogliosis, and neuronal cell death after spinal cord injury.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Mucosal adenosine triphosphate mediates serotonin release from ileal but not colonic guinea pig enterochromaffin cells.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

The P2X(7) receptor-pannexin connection to dye uptake and IL-1beta release

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

The distribution of P2X3 purine receptor subunits in the guinea pig enteric nervous system.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Cx43 hemichannels and gap junction channels in astrocytes are regulated oppositely by proinflammatory cytokines released from activated microglia.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Microglia proliferation is controlled by P2X7 receptors in a Pannexin-1-independent manner during early embryonic spinal cord invasion.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Extracellular ATP is a danger signal activating P2X7 receptor in lung inflammation and fibrosis

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Carbenoxolone Blockade of Neuronal Network Activity in Culture is not Mediated by an Action on Gap Junctions

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Role of cytokines in inflammatory bowel disease

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Purinergic control of T cell activation by ATP released through pannexin-1 hemichannels.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

ATP release by way of connexin 36 hemichannels mediates ischemic tolerance in vitro

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Pannexin 2 is expressed by postnatal hippocampal neural progenitors and modulates neuronal commitment

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Cellular distribution of the P2X4 ATP receptor mRNA in the brain and non-neuronal organs of rats

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Glial cells, but not interstitial cells, express P2X7, an ionotropic purinergic receptor, in rat gastrointestinal musculature

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

ATP-gated ion channel P2X(3) is increased in human inflammatory bowel disease.

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Genetic and Pharmacological Inactivation of the Purinergic P2RX7 Receptor Dampens Inflammation but Increases Tumor Incidence in a Mouse Model of Colitis-Associated Cancer

21 January 2018

1 reference

https://api.crossref.org/works/10.3389/FNINS.2016.00311

Differential effects of experimental ulcerative colitis on P2X7 receptor expression in enteric neurons

21 January 2018

1 reference

12 December 2020

P2Y1receptors mediate inhibitory purinergic neuromuscular transmission in the human colon

1 reference

12 December 2020

A role for TNF-alpha and mucosal T helper-1 cytokines in the pathogenesis of Crohn's disease

1 reference

12 December 2020

Expression and trans-synaptic regulation of P2x4 and P2z receptors for extracellular ATP in parotid acinar cells. Effects of parasympathetic denervation

1 reference

12 December 2020

Neurons respond directly to mechanical deformation with pannexin-mediated ATP release and autostimulation of P2X7 receptors

1 reference

12 December 2020

P2X7 receptor-Pannexin1 interaction mediates stress-induced interleukin-1 beta expression in human periodontal ligament cells

1 reference

12 December 2020

Extracellular-loop peptide antibodies reveal a predominant hemichannel organization of connexins in polarized intestinal cells

1 reference

12 December 2020

ATP release from activated neutrophils occurs via connexin 43 and modulates adenosine-dependent endothelial cell function

1 reference

12 December 2020

Prostaglandin ethanolamides attenuate damage in a human explant colitis model

1 reference

12 December 2020

Role of gap junctions in cardiac conduction and development: insights from the connexin knockout mice

1 reference

12 December 2020

Interleukin 12 is expressed and actively released by Crohn's disease intestinal lamina propria mononuclear cells

1 reference

12 December 2020

Expression of connexins 26, 32 and 43 in the human colon--an immunohistochemical study

1 reference

12 December 2020

P2Y1receptors mediate inhibitory neuromuscular transmission and enteric neuronal activation in small intestine

1 reference

12 December 2020