The distribution of the anti-HIV drug, tenofovir (PMPA), into the brain, CSF and choroid plexuses. (Q25257032)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16390539 AND SRC:MED&resulttype=core&format=json

15 January 2020

title

The distribution of the anti-HIV drug, tenofovir (PMPA), into the brain, CSF and choroid plexuses (English)

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15 January 2020

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2

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15 January 2020

Sarah A Thomas

series ordinal

3

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15 January 2020

author name string

Christy Anthonypillai

series ordinal

1

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15 January 2020

language of work or name

English

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publication date

3 January 2006

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Cerebrospinal Fluid Research

15 January 2020

published in

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15 January 2020

volume

3

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15 January 2020

issue

1

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page(s)

1

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Latent reservoirs of HIV: obstacles to the eradication of virus

15 January 2020

cites work

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28 September 2017

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28 September 2017

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Central nervous system perivascular cells are immunoregulatory cells that connect the CNS with the peripheral immune system

28 September 2017

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Phase i/ii trial of the pharmacokinetics, safety, and antiretroviral activity of tenofovir disoproxil fumarate in human immunodeficiency virus-infected adults

28 September 2017

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Therapeutic effects of nucleoside analogues on psychomotor slowing in HIV infection

28 September 2017

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Persistence of infectious HIV on follicular dendritic cells

28 September 2017

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Latency and viral persistence in HIV-1 infection

28 September 2017

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The multispecific organic anion transporter (OAT) family.

28 September 2017

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The transport of the anti-HIV drug, 2',3'-didehydro-3'-deoxythymidine (D4T), across the blood-brain and blood-cerebrospinal fluid barriers

28 September 2017

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Pharmacokinetics and bioavailability of the anti-human immunodeficiency virus nucleotide analog 9-[(R)-2-(phosphonomethoxy)propyl]adenine (PMPA) in dogs.

28 September 2017

1 reference

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Comparison of lipid-mediated blood-brain-barrier penetrability in neonates and adults

28 September 2017

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Evidence for a 'paravascular' fluid circulation in the mammalian central nervous system, provided by the rapid distribution of tracer protein throughout the brain from the subarachnoid space

28 September 2017

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Cellular localization of human immunodeficiency virus infection within the brains of acquired immune deficiency syndrome patients

28 September 2017

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28 September 2017

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Determining the antiviral activity of tenofovir disoproxil fumarate in treatment-naive chronically HIV-1-infected individuals

28 September 2017

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Long-term survival and virus production in human primary macrophages infected by human immunodeficiency virus

31 May 2018

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Anti-HIV activity of adefovir (PMEA) and PMPA in combination with antiretroviral compounds: in vitro analyses

31 May 2018

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Relationship between human immunodeficiency virus—associated dementia and viral load in cerebrospinal fluid and brain

31 May 2018

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Rapid distribution of intraventricularly administered sucrose into cerebrospinal fluid cisterns via subarachnoid velae in rat.

31 May 2018

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Kinetic analysis of [36Cl]-, [22Na]- and [3H]mannitol uptake into the in vivo choroid plexus-cerebrospinal fluid brain system: ontogeny of the blood brain and blood-CSF barriers

31 May 2018

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Brain distribution spaces of mannitol-3H, inulin-14C, and dextran-14C in the rat.

31 May 2018

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Differential permeability of cerebral capillary and choroid plexus to lanthanum ion

31 May 2018

1 reference

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Intracellular pharmacokinetics of tenofovir diphosphate, carbovir triphosphate, and lamivudine triphosphate in patients receiving triple-nucleoside regimens

31 May 2018

1 reference

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Early virologic failure in HIV-1 infected subjects on didanosine/tenofovir/efavirenz: 12-week results from a randomized trial

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1343584

Renal tubular transporters and antiviral drugs: an update

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1343584

Mouse reduced in osteosclerosis transporter functions as an organic anion transporter 3 and is localized at abluminal membrane of blood-brain barrier

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1343584

The distribution of the HIV protease inhibitor, ritonavir, to the brain, cerebrospinal fluid, and choroid plexuses of the guinea pig.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1343584

Mechanisms by which 2',3'-dideoxyinosine (ddI) crosses the guinea-pig CNS barriers; relevance to HIV therapy

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1343584

Tenofovir DF in antiretroviral-experienced patients: results from a 48-week, randomized, double-blind study

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1343584

Impaired organic anion transport in kidney and choroid plexus of organic anion transporter 3 (Oat3 (Slc22a8)) knockout mice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1343584

Expression and functional characterization of rat organic anion transporter 3 (rOat3) in the choroid plexus

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1343584

Therapeutic effects of nonnucleoside reverse transcriptase inhibitors on the central nervous system in HIV-1-infected patients

28 November 2018

1 reference

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The distribution of the anti-HIV drug, 2'3'-dideoxycytidine (ddC), across the blood-brain and blood-cerebrospinal fluid barriers and the influence of organic anion transport inhibitors.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1343584

CNS invasion by CD14 /CD16 peripheral blood-derived monocytes in HIV dementia: perivascular accumulation and reservoir of HIV infection

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1343584

Human renal organic anion transporter 1 (hOAT1) and its role in the nephrotoxicity of antiviral nucleotide analogs

28 November 2018

1 reference

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Residual human immunodeficiency virus (HIV) Type 1 RNA and DNA in lymph nodes and HIV RNA in genital secretions and in cerebrospinal fluid after suppression of viremia for 2 years

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1343584

Evidence for independent development of resistance to HIV-1 reverse transcriptase inhibitors in the cerebrospinal fluid.

28 November 2018

1 reference

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Antiretroviral resistance mutations in human immunodeficiency virus type 1 reverse transcriptase and protease from paired cerebrospinal fluid and plasma samples

28 November 2018

1 reference

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Localization of HIV-1 in human brain using polymerase chain reaction/in situ hybridization and immunocytochemistry

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1343584

Tenofovir disoproxil fumarate

28 November 2018

1 reference

12 December 2020

Full-length recombinant CD4 and recombinant gp120 inhibit fusion between HIV infected macrophages and uninfected CD4-expressing T-lymphoblastoid cells

1 reference

12 December 2020

Cellular and anatomical reservoirs of HIV-1 in patients receiving potent antiretroviral combination therapy

1 reference

12 December 2020

Mechanism of organic anion transport across the apical membrane of choroid plexus

1 reference

12 December 2020

Independent HIV replication in paired CSF and blood viral isolates during antiretroviral therapy

1 reference

12 December 2020

Identifiers

DOI

10.1186/1743-8454-3-1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16390539 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

15 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16390539 AND SRC:MED&resulttype=core&format=json

15 January 2020

PubMed publication ID

16390539

1 reference