Functional promoter upstream p53 regulatory sequence of IGFBP3 that is silenced by tumor specific methylation (Q24800130)

1

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Toshiyuki Shinji

2

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Hidenori Shiraha

3

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Kazuhiro Nouso

4

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Yoshiaki Iwasaki

5

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Eichiro Yumoto

6

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Toshiro Ono

7

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Norio Koide

Reduced expression of insulin-like growth factor binding protein-3 and its promoter hypermethylation in human hepatocellular carcinoma

8

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language of work or name

English

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publication date

20 January 2005

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published in

BMC Cancer

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volume

5

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issue

1

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page(s)

9

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cites work

1 reference

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Novel promoter polymorphism in insulin-like growth factor-binding protein-3: correlation with serum levels and interaction with known regulators

7 April 2017

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Induction of the growth inhibitor IGF-binding protein 3 by p53

7 April 2017

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Insulin-like growth factor binding protein-3. Organization of the human chromosomal gene and demonstration of promoter activity

7 April 2017

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A mouse skin multistage carcinogenesis model reflects the aberrant DNA methylation patterns of human tumors

7 April 2017

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Mechanisms underlying lack of insulin-like growth factor-binding protein-3 expression in non-small-cell lung cancer.

28 September 2017

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Overexpression of KIT in chromophobe renal cell carcinoma

28 September 2017

1 reference

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Nuclear effects: unexpected intracellular actions of insulin-like growth factor binding protein-3.

28 September 2017

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A possible role for insulin-like growth factor-binding protein-3 autocrine/paracrine loops in controlling hepatocellular carcinoma cell proliferation.

28 September 2017

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Insulin-like growth factor (IGF)-binding protein-3 mutants that do not bind IGF-I or IGF-II stimulate apoptosis in human prostate cancer cells

28 September 2017

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Butyrate, a histone deacetylase inhibitor, activates the human IGF binding protein-3 promoter in breast cancer cells: molecular mechanism involves an Sp1/Sp3 multiprotein complex

28 September 2017

1 reference

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Human papillomavirus type 16 E7 oncoprotein binds and inactivates growth-inhibitory insulin-like growth factor binding protein 3

28 September 2017

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Insulin-like growth factor (IGF)-binding protein-3 induces apoptosis and mediates the effects of transforming growth factor-beta1 on programmed cell death through a p53- and IGF-independent mechanism

28 September 2017

1 reference

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A mutant p53 that discriminates between p53-responsive genes cannot induce apoptosis

28 September 2017

1 reference

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Differential activation of target cellular promoters by p53 mutants with impaired apoptotic function

28 September 2017

1 reference

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Insulin-like growth factor binding protein 3 mediates retinoic acid- and transforming growth factor beta2-induced growth inhibition in human breast cancer cells.

28 September 2017

1 reference

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Insulin-like growth factor binding proteins and their role in controlling IGF actions

28 September 2017

1 reference

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Growth inhibition by insulin-like growth factor-binding protein-3 in T47D breast cancer cells requires transforming growth factor-beta (TGF-beta ) and the type II TGF-beta receptor

28 September 2017

1 reference

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Sequence alterations of insulin-like growth factor binding protein 3 in neoplastic and normal gastrointestinal tissues

30 May 2018

1 reference

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Growth inhibition by TGF-beta linked to suppression of retinoblastoma protein phosphorylation

30 May 2018

1 reference

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Differentially expressed genes in nonsmall cell lung cancer: expression profiling of cancer-related genes in squamous cell lung cancer

30 May 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186/1471-2407-5-9

Signaling through the Smad pathway by insulin-like growth factor-binding protein-3 in breast cancer cells. Relationship to transforming growth factor-beta 1 signaling.

21 January 2018

1 reference

Crossref

https://api.crossref.org/works/10.1186/1471-2407-5-9

Cell-specific localization of insulin-like growth factor binding protein mRNAs in rat liver

21 January 2018

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12 December 2020

Gene expression correlates of clinical prostate cancer behavior

1 reference

12 December 2020

Tumor necrosis factor alpha stimulates insulin-like growth factor binding protein 3 expression in cultured porcine Sertoli cells

1 reference

12 December 2020

Correlation of Insulin-Like Growth Factor-Binding Protein-3 Messenger RNA With Protein Expression in Primary Breast Cancer Tissues: Detection of Higher Levels in Tumors With Poor Prognostic Features

1 reference

12 December 2020

Further characterisation of the p53 responsive element--identification of new candidate genes for trans-activation by p53

1 reference

12 December 2020

Down-regulation of insulin-like growth factor binding proteins and growth modulation in hepatoma cells by retinoic acid

1 reference

12 December 2020

Identifiers

DOI

10.1186/1471-2407-5-9

1 reference

Dimensions Publication ID

1011688774

0 references

1 reference

1 reference

PubMed publication ID

15661074

1 reference