Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones (Q24798680)

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9 January 2020

title

Selective inhibition of HIV-1 reverse transcriptase-associated ribonuclease H activity by hydroxylated tropolones (English)

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9

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author name string

Scott R Budihas

1

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9 January 2020

Inna Gorshkova

2

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9 January 2020

Sergei Gaidamakov

3

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9 January 2020

Antony Wamiru

4

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9 January 2020

Marion K Bona

5

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9 January 2020

Michael A Parniak

6

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Robert J Crouch

7

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James B McMahon

8

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Stuart F J Le Grice

10

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9 January 2020

language of work or name

English

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publication date

1 March 2005

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9 January 2020

published in

Nucleic Acids Research

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volume

33

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issue

4

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9 January 2020

page(s)

1249-1256

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Two-metal ion mechanism of RNA cleavage by HIV RNase H and mechanism-based design of selective HIV RNase H inhibitors

9 January 2020

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A capillary electrophoretic assay for ribonuclease H activity.

7 April 2017

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28 September 2017

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28 September 2017

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A fluorescence-based high-throughput screening assay for inhibitors of human immunodeficiency virus-1 reverse transcriptase-associated ribonuclease H activity

28 September 2017

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Selective inhibitory DNA aptamers of the human RNase H1

28 September 2017

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Uncovering the complexities of retroviral ribonuclease H reveals its potential as a therapeutic target.

28 September 2017

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HIV-1 reverse transcriptase interaction with model RNA-DNA duplexes

28 September 2017

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Evaluation of retroviral ribonuclease H activity

28 September 2017

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Inhibition of HIV-1 reverse transcriptase-catalyzed DNA strand transfer reactions by 4-chlorophenylhydrazone of mesoxalic acid

28 September 2017

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Inhibitors of HIV-1 reverse transcriptase

28 September 2017

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Thujaplicin-copper chelates inhibit replication of human influenza viruses

28 September 2017

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Inhibition of the ribonuclease H and DNA polymerase activities of HIV-1 reverse transcriptase by N-(4-tert-butylbenzoyl)-2-hydroxy-1-naphthaldehyde hydrazone

28 September 2017

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Nevirapine alters the cleavage specificity of ribonuclease H of human immunodeficiency virus 1 reverse transcriptase

28 September 2017

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Sequence specific cleavage of messenger RNA by a modified ribonuclease H

28 September 2017

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Crystal structure of the ribonuclease H domain of HIV-1 reverse transcriptase

28 September 2017

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28 September 2017

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Mutations within the RNase H Domain of Human Immunodeficiency Virus Type 1 Reverse Transcriptase Abolish Virus Infectivity

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30 May 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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28 November 2018

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12 December 2020

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Inhibitors of DNA strand transfer reactions catalyzed by HIV-1 reverse transcriptase

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12 December 2020

Metal-ion stoichiometry of the HIV-1 RT ribonuclease H domain: evidence for two mutually exclusive sites leads to new mechanistic insights on metal-mediated hydrolysis in nucleic acid biochemistry

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12 December 2020

Identifiers

DOI

10.1093/NAR/GKI268

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:15741178 AND SRC:MED&resulttype=core&format=json

9 January 2020

1 reference

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9 January 2020

PubMed publication ID

15741178

2 references