Mre11 assembles linear DNA fragments into DNA damage signaling complexes (Q24796676)

April 2022 Public Data File from Crossref

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MDC1 is a mediator of the mammalian DNA damage checkpoint

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The Rad50 zinc-hook is a structure joining Mre11 complexes in DNA recombination and repair

7 April 2017

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ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway

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Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex

7 April 2017

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The 3' to 5' exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks

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The hMre11/hRad50 protein complex and Nijmegen breakage syndrome: linkage of double-strand break repair to the cellular DNA damage response

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Nibrin, a novel DNA double-strand break repair protein, is mutated in Nijmegen breakage syndrome

7 April 2017

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hMre11 and hRad50 Nuclear Foci Are Induced During the Normal Cellular Response to DNA Double-Strand Breaks †

7 April 2017

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Structural biochemistry and interaction architecture of the DNA double-strand break repair Mre11 nuclease and Rad50-ATPase

7 April 2017

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Sensing DNA damage through ATRIP recognition of RPA-ssDNA complexes

7 April 2017

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DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex

7 April 2017

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The DNA double-strand break repair gene hMRE11 is mutated in individuals with an ataxia-telangiectasia-like disorder

7 April 2017

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DNA double-stranded breaks induce histone H2AX phosphorylation on serine 139

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53BP1 and NFBD1/MDC1-Nbs1 function in parallel interacting pathways activating ataxia-telangiectasia mutated (ATM) in response to DNA damage

7 April 2017

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Checkpoint failure and chromosomal instability without lymphomagenesis in Mre11(ATLD1/ATLD1) mice

7 April 2017

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MDC1 is required for the intra-S-phase DNA damage checkpoint

7 April 2017

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DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation

7 April 2017

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An ATR- and Cdc7-dependent DNA damage checkpoint that inhibits initiation of DNA replication

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Human Rad50/Mre11 is a flexible complex that can tether DNA ends

7 April 2017

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Histone H2AX is phosphorylated in an ATR-dependent manner in response to replicational stress

7 April 2017

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ATM phosphorylates histone H2AX in response to DNA double-strand breaks

7 April 2017

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Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products

7 April 2017

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7 April 2017

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Cell cycle checkpoint signaling through the ATM and ATR kinases

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Vanillins--a novel family of DNA-PK inhibitors

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The MRN complex: coordinating and mediating the response to broken chromosomes

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Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage

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Specific recruitment of human cohesin to laser-induced DNA damage

28 September 2017

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28 September 2017

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DNA damage-dependent nuclear dynamics of the Mre11 complex

28 September 2017

1 reference

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ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response

28 September 2017

1 reference

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The Mre11 complex and ATM: collaborating to navigate S phase

28 September 2017

1 reference

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Mre11 is essential for the maintenance of chromosomal DNA in vertebrate cells

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406388

Nijmegen breakage syndrome: consequences of defective DNA double strand break repair

28 September 2017

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Disruption of mRad50 causes embryonic stem cell lethality, abnormal embryonic development, and sensitivity to ionizing radiation

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406388

Dynamics of DNA double-strand breaks revealed by clustering of damaged chromosome domains

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406388

Regulation of Mre11/Rad50 by Nbs1: effects on nucleotide-dependent DNA binding and association with ataxia-telangiectasia-like disorder mutant complexes.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406388

DNA replication-dependent nuclear dynamics of the Mre11 complex.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406388

Mre11 protein complex prevents double-strand break accumulation during chromosomal DNA replication.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406388

Nuclear retention of ATM at sites of DNA double strand breaks

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406388

Targeted disruption of the Nijmegen breakage syndrome gene NBS1 leads to early embryonic lethality in mice.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406388

Reconstitution of an ATM-dependent checkpoint that inhibits chromosomal DNA replication following DNA damage

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=406388

Trading places on DNA--a three-point switch underlies primer handoff from primase to the replicative DNA polymerase

28 November 2018

1 reference

12 December 2020

TPEN, a Zn2 /Fe2 chelator with low affinity for Ca2 , inhibits lamin assembly, destabilizes nuclear architecture and may independently protect nuclei from apoptosis in vitro

1 reference

12 December 2020

The cellular response to DNA double-strand breaks: defining the sensors and mediators

1 reference

12 December 2020

The many interfaces of Mre11

1 reference

12 December 2020

10.1371/JOURNAL.PBIO.0020110

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DOI

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PubMed publication ID

15138496

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