Cdc25B and Cdc25C differ markedly in their properties as initiators of mitosis (Q24685826)

5

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author name string

C Karlsson

1

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S Katich

2

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A Hagting

3

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I Hoffmann

A human homologue of the checkpoint kinase Cds1 directly inhibits Cdc25 phosphatase

4

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language of work or name

English

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publication date

9 August 1999

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published in

Journal of Cell Biology

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volume

146

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issue

3

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page(s)

573-84

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cites work

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The human Myt1 kinase preferentially phosphorylates Cdc2 on threonine 14 and localizes to the endoplasmic reticulum and Golgi complex

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Human Wee1 kinase inhibits cell division by phosphorylating p34cdc2 exclusively on Tyr15

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Human wee1 maintains mitotic timing by protecting the nucleus from cytoplasmically activated Cdc2 kinase

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Specific activation of cdc25 tyrosine phosphatases by B-type cyclins: Evidence for multiple roles of mitotic cyclins

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CRM1 is an export receptor for leucine-rich nuclear export signals

7 April 2017

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Regulation of p34CDC28 tyrosine phosphorylation is not required for entry into mitosis in S. cerevisiae

7 April 2017

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Translocation of cyclin B1 to the nucleus at prophase requires a phosphorylation-dependent nuclear import signal

7 April 2017

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Mitotic and G 2 Checkpoint Control: Regulation of 14-3-3 Protein Binding by Phosphorylation of Cdc25C on Serine-216

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Conservation of the Chk1 Checkpoint Pathway in Mammals: Linkage of DNA Damage to Cdk Regulation Through Cdc25

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7 April 2017

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Isolation of a human cyclin cDNA: evidence for cyclin mRNA and protein regulation in the cell cycle and for interaction with p34cdc2

7 April 2017

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Control of cyclin B1 localization through regulated binding of the nuclear export factor CRM1

7 April 2017

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Cdc25A is a novel phosphatase functioning early in the cell cycle

7 April 2017

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Leptomycin B is an inhibitor of nuclear export: inhibition of nucleo-cytoplasmic translocation of the human immunodeficiency virus type 1 (HIV-1) Rev protein and Rev-dependent mRNA

7 April 2017

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Negative regulation of mitosis by wee1 , a gene encoding a protein kinase homolog

7 April 2017

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Tyrosine phosphorylation of the fission yeast cdc2 protein kinase regulates entry into mitosis

7 April 2017

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Universal control mechanism regulating onset of M-phase

7 April 2017

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Direct repeats as selective response elements for the thyroid hormone, retinoic acid, and vitamin D3 receptors

7 April 2017

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7 April 2017

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The decision to enter mitosis

21 January 2018

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The cdc25B phosphatase is essential for the G2/M phase transition in human cells

28 September 2017

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Tyrosine phosphorylation of cdc2 is required for the replication checkpoint in Schizosaccharomyces pombe

28 September 2017

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Replication checkpoint enforced by kinases Cds1 and Chk1.

28 September 2017

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Phosphorylation of Human CDC25B Phosphatase by CDK1-Cyclin A Triggers Its Proteasome-dependent Degradation

28 September 2017

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A dual-specificity phosphatase Cdc25B is an unstable protein and triggers p34(cdc2)/cyclin B activation in hamster BHK21 cells arrested with hydroxyurea.

28 September 2017

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28 September 2017

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The proteolysis of mitotic cyclins in mammalian cells persists from the end of mitosis until the onset of S phase

28 September 2017

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Protein sequence requirements for function of the human T-cell leukemia virus type 1 Rex nuclear export signal delineated by a novel in vivo randomization-selection assay

28 September 2017

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Pub1 acts as an E6-AP-like protein ubiquitiin ligase in the degradation of cdc25.

28 September 2017

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Phosphorylation and activation of human cdc25-C by cdc2--cyclin B and its involvement in the self-amplification of MPF at mitosis

28 September 2017

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Membrane localization of the kinase which phosphorylates p34cdc2 on threonine 14

28 September 2017

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Closing the cell cycle circle in yeast: G2 cyclin proteolysis initiated at mitosis persists until the activation of G1 cyclins in the next cycle.

28 September 2017

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Phosphorylation and activation of the Xenopus Cdc25 phosphatase in the absence of Cdc2 and Cdk2 kinase activity

28 September 2017

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Activation of the phosphatase activity of human cdc25A by a cdk2-cyclin E dependent phosphorylation at the G1/S transition

28 September 2017

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p55CDC25 is a nuclear protein required for the initiation of mitosis in human cells.

28 September 2017

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p80cdc25 mitotic inducer is the tyrosine phosphatase that activates p34cdc2 kinase in fission yeast

28 September 2017

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mik1 and wee1 cooperate in the inhibitory tyrosine phosphorylation of cdc2.

28 September 2017

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An additional homolog of the fission yeast cdc25 gene occurs in humans and is highly expressed in some cancer cells.

28 September 2017

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An extra copy of nimEcyclinB elevates pre-MPF levels and partially suppresses mutation of nimTcdc25 in Aspergillus nidulans

28 September 2017

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cdc25 is a nuclear protein expressed constitutively throughout the cell cycle in nontransformed mammalian cells

28 September 2017

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Periodic changes in phosphorylation of the Xenopus cdc25 phosphatase regulate its activity

28 September 2017

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p107wee1 is a dual-specificity kinase that phosphorylates p34cdc2 on tyrosine 15

28 September 2017

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Regulatory roles of cyclin dependent kinase phosphorylation in cell cycle control

28 September 2017

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MPF localization is controlled by nuclear export

28 September 2017

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30 May 2018

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An indelible lineage marker for Xenopus using a mutated green fluorescent protein

30 May 2018

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cdc25 functions as an inducer in the mitotic control of fission yeast

30 May 2018

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The mitotic inducer nim1 functions in a regulatory network of protein kinase homologs controlling the initiation of mitosis

30 May 2018

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30 May 2018

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30 May 2018

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S-phase feedback control in budding yeast independent of tyrosine phosphorylation of P34cdc28

30 May 2018

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The cdc25 protein contains an intrinsic phosphatase activity

30 May 2018

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Regulation of the cdc25 protein during the cell cycle in Xenopus extracts

30 May 2018

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Coupling of mitosis to the completion of S phase in Xenopus occurs via modulation of the tyrosine kinase that phosphorylates p34cdc2.

30 May 2018

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Mechanisms of p34cdc2 regulation

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Uncoupling of obesity from insulin resistance through a targeted mutation in aP2, the adipocyte fatty acid binding protein

21 January 2018

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Nuclear localization of Cdc25 is regulated by DNA damage and a 14-3-3 protein

21 January 2018

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Myt1: a membrane-associated inhibitory kinase that phosphorylates Cdc2 on both threonine-14 and tyrosine-15.

21 January 2018

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Purification and cloning of a protein kinase that phosphorylates and activates the polo-like kinase Plx1.

21 January 2018

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Cdc25 Mitotic Inducer Targeted by Chk1 DNA Damage Checkpoint Kinase

21 January 2018

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Localization of cell cycle regulators by immunofluorescence

21 January 2018

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Cellular substrates of p34cdc2 and its companion cyclin-dependent kinases

21 January 2018

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Purification and molecular cloning of Plx1, a Cdc25-regulatory kinase from Xenopus egg extracts

21 January 2018

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Mutation of fission yeast cell cycle control genes abolishes dependence of mitosis on DNA replication

28 November 2018

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12 December 2020

Cytoplasmic accumulation of cdc25B phosphatase in mitosis triggers centrosomal microtubule nucleation in HeLa cells

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Hyperphosphorylation of the N-terminal Domain of Cdc25 Regulates Activity toward Cyclin B1/Cdc2 But Not Cyclin A/Cdk2

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Ultraviolet light-induced G2 phase cell cycle checkpoint blocks cdc25-dependent progression into mitosis

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p53 regulates Cdc2 independently of inhibitory phosphorylation to reinforce radiation-induced G2 arrest in human cells

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