Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria (Q24681355)

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30 December 2019

title

Tbx3 controls the sinoatrial node gene program and imposes pacemaker function on the atria (English)

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30 December 2019

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GOA release 2020-03-11

author

Arie O. Verkerk

4

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30 December 2019

Vincent M. Christoffels

14

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30 December 2019

author name string

Willem M H Hoogaars

1

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30 December 2019

Angela Engel

2

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30 December 2019

Janynke F Brons

3

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30 December 2019

Frederik J de Lange

5

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30 December 2019

L Y Elaine Wong

6

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30 December 2019

Martijn L Bakker

7

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30 December 2019

Danielle E Clout

8

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30 December 2019

Vincent Wakker

9

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30 December 2019

Phil Barnett

10

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30 December 2019

Jan Hindrik Ravesloot

11

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30 December 2019

Antoon F M Moorman

12

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30 December 2019

E Etienne Verheijck

13

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30 December 2019

language of work or name

English

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publication date

1 May 2007

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30 December 2019

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17473172 AND SRC:MED&resulttype=core&format=json

30 December 2019

volume

21

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issue

9

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30 December 2019

page(s)

1098-1112

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The Form and Nature of the Muscular Connections between the Primary Divisions of the Vertebrate Heart

30 December 2019

cites work

1 reference

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T-box transcription factor Tbx2 represses differentiation and formation of the cardiac chambers

7 April 2017

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Pacemaker channel dysfunction in a patient with sinus node disease

7 April 2017

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Cooperative action of Tbx2 and Nkx2.5 inhibits ANF expression in the atrioventricular canal: implications for cardiac chamber formation

7 April 2017

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TBX-3, the gene mutated in Ulnar-Mammary Syndrome, is a negative regulator of p19ARF and inhibits senescence

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Molecular pathway for the localized formation of the sinoatrial node

7 April 2017

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Bradycardia and slowing of the atrioventricular conduction in mice lacking CaV3.1/alpha1G T-type calcium channels

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Tbx2 is essential for patterning the atrioventricular canal and for morphogenesis of the outflow tract during heart development

7 April 2017

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Mammary gland, limb and yolk sac defects in mice lacking Tbx3, the gene mutated in human ulnar mammary syndrome

7 April 2017

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Hop is an unusual homeobox gene that modulates cardiac development

7 April 2017

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Dysregulation of connexins and inactivation of NFATc1 in the cardiovascular system of Nkx2-5 null mutants

7 April 2017

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Homeobox protein Hop functions in the adult cardiac conduction system

7 April 2017

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The hyperpolarization-activated channel HCN4 is required for the generation of pacemaker action potentials in the embryonic heart

7 April 2017

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Expression of the hyperpolarization-activated cyclic nucleotide-gated cation channel HCN4 during mouse heart development

7 April 2017

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Slowed conduction and ventricular tachycardia after targeted disruption of the cardiac sodium channel gene Scn5a

7 April 2017

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A murine model of Holt-Oram syndrome defines roles of the T-box transcription factor Tbx5 in cardiogenesis and disease

7 April 2017

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7 April 2017

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7 April 2017

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High-efficiency deleter mice show that FLPe is an alternative to Cre-loxP

7 April 2017

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7 April 2017

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Connexin30.2 containing gap junction channels decelerate impulse propagation through the atrioventricular node

28 September 2017

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Novel TBX3 mutation data in families with ulnar-mammary syndrome indicate a genotype-phenotype relationship: mutations that do not disrupt the T-domain are associated with less severe limb defects

28 September 2017

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Altered right atrial excitation and propagation in connexin40 knockout mice

28 September 2017

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28 September 2017

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Congenital heart disease reminiscent of partial trisomy 2p syndrome in mice transgenic for the transcription factor Lbh.

28 September 2017

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28 September 2017

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Specific pattern of ionic channel gene expression associated with pacemaker activity in the mouse heart

28 September 2017

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28 September 2017

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Tbx2 represses expression of Connexin43 in osteoblastic-like cells.

28 September 2017

1 reference

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The transcriptional repressor Tbx3 delineates the developing central conduction system of the heart.

28 September 2017

1 reference

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28 September 2017

1 reference

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Pacemaker channels and sinus node arrhythmia

28 September 2017

1 reference

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Cardiac chamber formation: development, genes, and evolution.

28 September 2017

1 reference

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Atrial cardiomyocyte-specific expression of Cre recombinase driven by an Nppa gene fragment.

28 September 2017

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Induction and patterning of the cardiac conduction system.

28 September 2017

1 reference

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Loss of the Lkb1 tumour suppressor provokes intestinal polyposis but resistance to transformation

28 September 2017

1 reference

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Biological pacemaker created by gene transfer

28 September 2017

1 reference

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Differential distribution of cardiac ion channel expression as a basis for regional specialization in electrical function

28 September 2017

1 reference

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The sinoatrial node, a heterogeneous pacemaker structure

28 September 2017

1 reference

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Molecular and functional heterogeneity of hyperpolarization-activated pacemaker channels in the mouse CNS.

28 September 2017

1 reference

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Development of the cardiac conduction system involves recruitment within a multipotent cardiomyogenic lineage.

28 September 2017

1 reference

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Gene recombination in postmitotic cells. Targeted expression of Cre recombinase provokes cardiac-restricted, site-specific rearrangement in adult ventricular muscle in vivo.

28 September 2017

1 reference

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Site-specific recombination of a transgene in fertilized eggs by transient expression of Cre recombinase.

28 September 2017

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Conditional differentiation of heart- and smooth muscle-derived cells transformed by a temperature-sensitive mutant of SV40 T antigen

28 September 2017

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Ultrastructure of DNA-synthesizing and mitotically dividing myocytes in sinoatrial node of mouse embryonal heart

28 September 2017

1 reference

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Bioartificial sinus node constructed via in vivo gene transfer of an engineered pacemaker HCN Channel reduces the dependence on electronic pacemaker in a sick-sinus syndrome model

30 May 2018

1 reference

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Requirement of neuronal- and cardiac-type sodium channels for murine sinoatrial node pacemaking

28 November 2018

1 reference

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Sensitive nonradioactive detection of mRNA in tissue sections: novel application of the whole-mount in situ hybridization protocol

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1855235

Organisation of the mouse sinoatrial node: structure and expression of HCN channels

28 November 2018

1 reference

12 December 2020

Functional and morphological organization of the rabbit sinus node

1 reference

12 December 2020

Electrophysiological features of the mouse sinoatrial node in relation to connexin distribution

1 reference

12 December 2020

Extended atrial conduction system characterised by the expression of the HCN4 channel and connexin45

1 reference

12 December 2020

Patterning the vertebrate heart

1 reference

12 December 2020

Identifiers

DOI

10.1101/GAD.416007

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17473172 AND SRC:MED&resulttype=core&format=json

30 December 2019

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17473172 AND SRC:MED&resulttype=core&format=json

30 December 2019

PubMed publication ID

17473172

2 references