The C2 domain of the Rsp5 ubiquitin ligase binds membrane phosphoinositides and directs ubiquitination of endosomal cargo (Q24677536)

Human VPS34 is required for internal vesicle formation within multivesicular endosomes

GOA release 2020-03-11

protein ubiquitination

1 reference

Rebecca Dunn

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Deborah A Klos

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2

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Adam S Adler

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3

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Linda Hicke

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4

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language of work or name

English

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publication date

April 2004

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published in

Journal of Cell Biology

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volume

165

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issue

1

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page(s)

135-44

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cites work

1 reference

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Tsg101 and the vacuolar protein sorting pathway are essential for HIV-1 budding

7 April 2017

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TSG101/mammalian VPS23 and mammalian VPS28 interact directly and are recruited to VPS4-induced endosomes

7 April 2017

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The Vps4p AAA ATPase regulates membrane association of a Vps protein complex required for normal endosome function

7 April 2017

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The C2 domain of the ubiquitin protein ligase Nedd4 mediates Ca2 -dependent plasma membrane localization

7 April 2017

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The C2 domain calcium-binding motif: structural and functional diversity

7 April 2017

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Crystal structure of the PTEN tumor suppressor: implications for its phosphoinositide phosphatase activity and membrane association

7 April 2017

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Mechanisms underlying ubiquitination

7 April 2017

1 reference

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Endosome-associated complex, ESCRT-II, recruits transport machinery for protein sorting at the multivesicular body

7 April 2017

1 reference

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Escrt-III: an endosome-associated heterooligomeric protein complex required for mvb sorting

7 April 2017

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Vac14 controls PtdIns(3,5)P(2) synthesis and Fab1-dependent protein trafficking to the multivesicular body

7 April 2017

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A transmembrane ubiquitin ligase required to sort membrane proteins into multivesicular bodies

7 April 2017

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Sorting of proteins into multivesicular bodies: ubiquitin-dependent and -independent targeting

7 April 2017

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Ubiquitin-dependent sorting into the multivesicular body pathway requires the function of a conserved endosomal protein sorting complex, ESCRT-I.

7 April 2017

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Components of a ubiquitin ligase complex specify polyubiquitination and intracellular trafficking of the general amino acid permease

7 April 2017

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Domains of the Rsp5 ubiquitin-protein ligase required for receptor-mediated and fluid-phase endocytosis

7 April 2017

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Activation of a membrane-bound transcription factor by regulated ubiquitin/proteasome-dependent processing.

7 April 2017

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Rsp5 ubiquitin-protein ligase mediates DNA damage-induced degradation of the large subunit of RNA polymerase II in Saccharomyces cerevisiae

7 April 2017

1 reference

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Cytosolic Sec13p complex is required for vesicle formation from the endoplasmic reticulum in vitro.

7 April 2017

1 reference

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Morphological classification of the yeast vacuolar protein sorting mutants: evidence for a prevacuolar compartment in class E vps mutants

7 April 2017

1 reference

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Getting started with yeast

7 April 2017

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A new vital stain for visualizing vacuolar membrane dynamics and endocytosis in yeast

7 April 2017

1 reference

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Receptor downregulation and multivesicular-body sorting

7 April 2017

1 reference

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Inositol-1,3,4,5-tetrakisphosphate binding to C2B domain of IP4BP/synaptotagmin II

7 April 2017

1 reference

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Specificity and promiscuity in phosphoinositide binding by pleckstrin homology domains

7 April 2017

1 reference

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Fab1p PtdIns(3)P 5-kinase function essential for protein sorting in the multivesicular body

7 April 2017

1 reference

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Regulation of Membrane Protein Transport by Ubiquitin and Ubiquitin-Binding Proteins

7 April 2017

1 reference

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A single motif responsible for ubiquitin recognition and monoubiquitination in endocytic proteins

7 April 2017

1 reference

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Ubiquitination of a yeast plasma membrane receptor signals its ligand-stimulated endocytosis

7 April 2017

1 reference

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Protein sorting into multivesicular endosomes

7 April 2017

1 reference

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C2 domain of protein kinase C alpha: elucidation of the membrane docking surface by site-directed fluorescence and spin labeling

28 September 2017

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Comm sorts robo to control axon guidance at the Drosophila midline.

28 September 2017

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The C2A domain of JFC1 binds to 3'-phosphorylated phosphoinositides and directs plasma membrane association in living cells.

28 September 2017

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Epsins and Vps27p/Hrs contain ubiquitin-binding domains that function in receptor endocytosis

28 September 2017

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Membrane targeting by C1 and C2 domains

28 September 2017

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Deubiquitination step in the endocytic pathway of yeast plasma membrane proteins: crucial role of Doa4p ubiquitin isopeptidase.

28 September 2017

1 reference

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Inositol lipids as spatial regulators of membrane traffic

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172079

Localization of the Rsp5p ubiquitin-protein ligase at multiple sites within the endocytic pathway

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172079

Mammalian tumor susceptibility gene 101 (TSG101) and the yeast homologue, Vps23p, both function in late endosomal trafficking.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172079

Role of the ENTH domain in phosphatidylinositol-4,5-bisphosphate binding and endocytosis.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172079

Polar transmembrane domains target proteins to the interior of the yeast vacuole

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172079

Signaling and subcellular targeting by membrane-binding domains

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172079

Ubiquitination and endocytosis of plasma membrane proteins: role of Nedd4/Rsp5p family of ubiquitin-protein ligases

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172079

Phosphoinositide signaling and the regulation of membrane trafficking in yeast

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172079

Rsp5 WW domains interact directly with the carboxyl-terminal domain of RNA polymerase II.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172079

Calcium-dependent switching of the specificity of phosphoinositide binding to synaptotagmin

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172079

Ubiquitin is required for sorting to the vacuole of the yeast general amino acid permease, Gap1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172079

Ubiquitination mediated by the Npi1p/Rsp5p ubiquitin-protein ligase is required for endocytosis of the yeast uracil permease

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2172079

Basic Medical Research Award. The ubiquitin system

30 May 2018

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Drosophila Nedd4, a ubiquitin ligase, is recruited by Commissureless to control cell surface levels of the roundabout receptor

21 January 2018

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https://api.crossref.org/works/10.1083/JCB.200309026

Rapid protein extraction fromSaccharomyces cerevisiae

21 January 2018

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High-yield expression and purification of recombinant proteins in bacteria: a versatile vector for glutathione S-transferase fusion proteins containing two protease cleavage sites

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12 December 2020

Binding kinetics and ligand specificity for the interactions of the C2B domain of synaptogmin II with inositol polyphosphates and phosphoinositides

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12 December 2020

Ubiquitin Sorts Proteins into the Intralumenal Degradative Compartment of the Late-Endosome/Vacuole

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The C2 domains of Rabphilin3A specifically bind phosphatidylinositol 4,5-bisphosphate containing vesicles in a Ca2 -dependent manner. In vitro characteristics and possible significance

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