The active metabolite of Clopidogrel disrupts P2Y12 receptor oligomers and partitions them out of lipid rafts (Q24675155)

2

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Nathalie Delesque-Touchard

3

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Catherine Labouret

4

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Caroline Hervé

5

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Marie-Françoise Uzabiaga

6

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Jean-Marie Pereillo

7

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Jean-Michel Culouscou

8

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Françoise Bono

9

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Pascual Ferrara

10

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Jean-Marc Herbert

Proceedings of the National Academy of Sciences of the United States of America

11

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language of work or name

English

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publication date

18 July 2006

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published in

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volume

103

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issue

29

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page(s)

11069-74

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cites work

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21 January 2018

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Constitutive Agonist-independent CCR5 Oligomerization and Antibody-mediated Clustering Occurring at Physiological Levels of Receptors

21 January 2018

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Adenosine A2A-dopamine D2 receptor-receptor heteromerization: qualitative and quantitative assessment by fluorescence and bioluminescence energy transfer

21 January 2018

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C5a receptor oligomerization. II. Fluorescence resonance energy transfer studies of a human G protein-coupled receptor expressed in yeast

21 January 2018

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The fourth transmembrane segment forms the interface of the dopamine D2 receptor homodimer.

21 January 2018

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Oligomerization of the alpha 1a- and alpha 1b-adrenergic receptor subtypes. Potential implications in receptor internalization

21 January 2018

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Oxytocin and Vasopressin V1a and V2 Receptors Form Constitutive Homo- and Heterodimers during Biosynthesis

21 January 2018

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Ligand-independent CXCR2 dimerization

21 January 2018

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Agonist-induced translocation of the kinin B(1) receptor to caveolae-related rafts.

21 January 2018

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Agonist-modulated targeting of the EDG-1 receptor to plasmalemmal caveolae. eNOS activation by sphingosine 1-phosphate and the role of caveolin-1 in sphingolipid signal transduction.

21 January 2018

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Light- and guanosine 5'-3-O-(thio)triphosphate-sensitive localization of a G protein and its effector on detergent-resistant membrane rafts in rod photoreceptor outer segments

21 January 2018

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P2y(12), a new platelet ADP receptor, target of clopidogrel

21 January 2018

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Pharmacological characterization of the human P2Y13 receptor

21 January 2018

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Identification and function of disulfide bridges in the extracellular domains of the angiotensin II type 2 receptor

21 January 2018

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Estradiol and testosterone modulate the anesthetic action of the GABA-A agonist THIP, but not of the neurosteroid 3alpha,5beta-pregnanolone in the rat.

21 January 2018

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Suppression of GABA(B) receptor function in vivo by disulfide reducing agent, DL-dithiothreitol (DTT).

21 January 2018

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Aggregation of Blood Platelets by Adenosine Diphosphate and its Reversal

28 November 2018

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Deficiency of (33P)2MeS-ADP binding sites on platelets with secretion defect, normal granule stores and normal thromboxane A2 production. Evidence that ADP potentiates platelet secretion independently of the formation of large platelet aggregates an

21 January 2018

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Dynamic Targeting of the Agonist-stimulated m2 Muscarinic Acetylcholine Receptor to Caveolae in Cardiac Myocytes

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Bradykinin Sequesters B2 Bradykinin Receptors and the Receptor-coupled Gα Subunits Gαq and Gαiin Caveolae in DDT1 MF-2 Smooth Muscle Cells

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Activated cardiac adenosine A(1) receptors translocate out of caveolae

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Role of disulfides and sulfhydryl groups in agonist and antagonist binding in serotonin1A receptors from bovine hippocampus

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Identification and biological activity of the active metabolite of clopidogrel

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Identifiers

DOI

10.1073/PNAS.0510446103

1 reference

ADS bibcode

2006PNAS..10311069S

0 references

1 reference

1 reference

PubMed publication ID

16835302

1 reference