Phenotype, localization, and mechanism of suppression of CD4( )CD25( ) human thymocytes (Q24673317)

2

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Francesco Liotta

3

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Elena Lazzeri

4

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Roberto Manetti

5

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Vittorio Vanini

6

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Paola Romagnani

7

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Enrico Maggi

8

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Sergio Romagnani

Journal of Experimental Medicine

9

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language of work or name

English

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publication date

5 August 2002

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published in

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volume

196

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issue

3

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page(s)

379-87

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cites work

Cytotoxic T lymphocyte-associated antigen 4 plays an essential role in the function of CD25( )CD4( ) regulatory cells that control intestinal inflammation

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Macrophage-derived chemokine and EBI1-ligand chemokine attract human thymocytes in different stage of development and are produced by distinct subsets of medullary epithelial cells: possible implications for negative selection

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Interferon-inducible protein 10, monokine induced by interferon gamma, and interferon-inducible T-cell alpha chemoattractant are produced by thymic epithelial cells and attract T-cell receptor (TCR) alphabeta CD8 single-positive T cells, [...]

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Cell contact-dependent immunosuppression by CD4( )CD25( ) regulatory T cells is mediated by cell surface-bound transforming growth factor beta

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Suppression of IL-2-induced T cell proliferation and phosphorylation of STAT3 and STAT5 by tumor-derived TGF beta is reversed by IL-15.

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Human cd25( )cd4( ) t regulatory cells suppress naive and memory T cell proliferation and can be expanded in vitro without loss of function.

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Human CD4( )CD25( ) thymocytes and peripheral T cells have immune suppressive activity in vitro

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Immunologic self-tolerance maintained by CD25( )CD4( ) regulatory T cells constitutively expressing cytotoxic T lymphocyte-associated antigen 4.

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Identification and functional characterization of human CD4( )CD25( ) T cells with regulatory properties isolated from peripheral blood

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A role for TGF-beta in the generation and expansion of CD4 CD25 regulatory T cells from human peripheral blood

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https://api.crossref.org/works/10.1084/JEM.20020110

Unique chemotactic response profile and specific expression of chemokine receptors CCR4 and CCR8 by CD4( )CD25( ) regulatory T cells

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CRTH2 is the most reliable marker for the detection of circulating human type 2 Th and type 2 T cytotoxic cells in health and disease

21 January 2018

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CD4 CD25high regulatory cells in human peripheral blood

21 January 2018

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28 November 2018

Identifiers

DOI

10.1084/JEM.20020110

1 reference

1 reference

1 reference

PubMed publication ID

12163566

1 reference