Reactive oxygen species are essential for autophagy and specifically regulate the activity of Atg4 (Q24670840)

2

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Ephraim Fass

3

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author name string

Ruth Scherz-Shouval

1

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Hagai Shorer

4

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Lidor Gil

HsAtg4B/HsApg4B/autophagin-1 cleaves the carboxyl termini of three human Atg8 homologues and delipidates microtubule-associated protein light chain 3- and GABAA receptor-associated protein-phospholipid conjugates

5

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language of work or name

English

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publication date

4 April 2007

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published in

The EMBO Journal

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volume

26

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issue

7

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page(s)

1749-60

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cites work

1 reference

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LC3, GABARAP and GATE16 localize to autophagosomal membrane depending on form-II formation

7 April 2017

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The COOH terminus of GATE-16, an intra-Golgi transport modulator, is cleaved by the human cysteine protease HsApg4A

7 April 2017

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Human autophagins, a family of cysteine proteinases potentially implicated in cell degradation by autophagy

7 April 2017

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The pre-autophagosomal structure organized by concerted functions of APG genes is essential for autophagosome formation

7 April 2017

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Dissection of autophagosome formation using Apg5-deficient mouse embryonic stem cells

7 April 2017

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LC3, a mammalian homologue of yeast Apg8p, is localized in autophagosome membranes after processing

7 April 2017

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The reversible modification regulates the membrane-binding state of Apg8/Aut7 essential for autophagy and the cytoplasm to vacuole targeting pathway

7 April 2017

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GATE-16, a membrane transport modulator, interacts with NSF and the Golgi v-SNARE GOS-28

7 April 2017

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Formation process of autophagosome is traced with Apg8/Aut7p in yeast

7 April 2017

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GABA(A)-receptor-associated protein links GABA(A) receptors and the cytoskeleton

7 April 2017

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A ubiquitin-like system mediates protein lipidation

7 April 2017

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Aut2p and Aut7p, two novel microtubule-associated proteins are essential for delivery of autophagic vesicles to the vacuole

7 April 2017

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A short mitochondrial form of p19ARF induces autophagy and caspase-independent cell death

7 April 2017

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Autophagy and signaling: their role in cell survival and cell death

7 April 2017

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LC3 conjugation system in mammalian autophagy

7 April 2017

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Mouse Apg16L, a novel WD-repeat protein, targets to the autophagic isolation membrane with the Apg12-Apg5 conjugate

7 April 2017

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Molecular dissection of autophagy: two ubiquitin-like systems

7 April 2017

1 reference

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Molecular characterization of light chain 3. A microtubule binding subunit of MAP1A and MAP1B

7 April 2017

1 reference

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A single protease, Apg4B, is specific for the autophagy-related ubiquitin-like proteins GATE-16, MAP1-LC3, GABARAP, and Apg8L

7 April 2017

1 reference

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Autophagy in health and disease: a double-edged sword

7 April 2017

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Regulation of an ATG7-beclin 1 program of autophagic cell death by caspase-8

7 April 2017

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A Unified Nomenclature for Yeast Autophagy-Related Genes

7 April 2017

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Distinct classes of phosphatidylinositol 3'-kinases are involved in signaling pathways that control macroautophagy in HT-29 cells

7 April 2017

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WWW-query: an on-line retrieval system for biological sequence banks

7 April 2017

1 reference

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Autophagic programmed cell death by selective catalase degradation

7 April 2017

1 reference

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Oxidative stress and autophagy

28 September 2017

1 reference

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The crystal structure of human Atg4b, a processing and de-conjugating enzyme for autophagosome-forming modifiers

28 September 2017

1 reference

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Structural basis for the specificity and catalysis of human Atg4B responsible for mammalian autophagy

28 September 2017

1 reference

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Stress, protein (mis)folding, and signaling: the redox connection

28 September 2017

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Autophagy: in sickness and in health

28 September 2017

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Influence of induced reactive oxygen species in p53-mediated cell fate decisions.

28 September 2017

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Oxidative stress-induced apoptosis is mediated by ERK1/2 phosphorylation

28 September 2017

1 reference

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Class III phosphoinositide 3-kinase--Beclin1 complex mediates the amino acid-dependent regulation of autophagy in C2C12 myotubes.

28 September 2017

1 reference

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Metal and redox modulation of cysteine protein function

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847657

Autophagy in yeast: a review of the molecular machinery

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847657

Membrane proximal ERK signaling is required for M-calpain activation downstream of epidermal growth factor receptor signaling.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847657

Scavenging of extracellular H2O2 by catalase inhibits the proliferation of HER-2/Neu-transformed rat-1 fibroblasts through the induction of a stress response

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847657

Oxidative stress and cytotoxicity induced by ferric-nitrilotriacetate in HepG2 cells that express cytochrome P450 2E1.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847657

Different subcellular distribution of caspase-3 and caspase-7 following Fas-induced apoptosis in mouse liver

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847657

Lipid oxidation and autophagy in yeast

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847657

Microtubules support production of starvation-induced autophagosomes but not their targeting and fusion with lysosomes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847657

Oxidant-mediated AA release from astrocytes involves cPLA(2) and iPLA(2).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847657

Effects of inhibitors of the vacuolar proton pump on hepatic heterophagy and autophagy

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1847657

Autophagy and aging--when "all you can eat" is yourself

28 November 2018

1 reference

12 December 2020

Detection of picomole levels of hydroperoxides using a fluorescent dichlorofluorescein assay

1 reference

12 December 2020

Significant levels of oxidants are generated by isolated cardiomyocytes during ischemia prior to reperfusion

1 reference

12 December 2020

Reactive oxygen intermediates as mediators of programmed cell death in plants and animals

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12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7601623

1 reference

1 reference

1 reference

PubMed publication ID

17347651

1 reference