AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist (Q24652842)

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29 January 2020

title

AGTR1 overexpression defines a subset of breast cancer and confers sensitivity to losartan, an AGTR1 antagonist (English)

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29 January 2020

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1 reference

2

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Qi Cao

3

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Shanker Kalyana-Sundaram

7

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Sooryanarayana Varambally

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15

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4

Scott A Tomlins

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29 January 2020

author name string

Daniel R Rhodes

1

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Rohit Mehra

5

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Bharathi Laxman

6

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Robert J Lonigro

8

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Beth E Helgeson

9

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Mahaveer S Bhojani

10

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Alnawaz Rehemtulla

11

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Celina G Kleer

12

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Daniel F Hayes

13

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Peter C Lucas

14

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Arul M Chinnaiyan

16

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language of work or name

English

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publication date

1 June 2009

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Proceedings of the National Academy of Sciences of the United States of America

29 January 2020

published in

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volume

106

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issue

25

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page(s)

10284-10289

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Recurrent fusion of TMPRSS2 and ETS transcription factor genes in prostate cancer.

29 January 2020

cites work

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7 April 2017

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A gene-expression signature as a predictor of survival in breast cancer

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Human breast cancer: correlation of relapse and survival with amplification of the HER-2/neu oncogene

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AT1 receptor is present in glioma cells; its blockage reduces the growth of rat glioma

7 April 2017

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Trastuzumab plus adjuvant chemotherapy for operable HER2-positive breast cancer

7 April 2017

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Gene-expression profiles to predict distant metastasis of lymph-node-negative primary breast cancer

7 April 2017

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Large-scale meta-analysis of cancer microarray data identifies common transcriptional profiles of neoplastic transformation and progression

7 April 2017

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The role of angiotensin II in the regulation of breast cancer cell adhesion and invasion

7 April 2017

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An expression signature for p53 status in human breast cancer predicts mutation status, transcriptional effects, and patient survival

28 September 2017

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Functional expression of the angiotensin II type 1 receptor in human ovarian carcinoma cells and its blockade therapy resulting in suppression of tumor invasion, angiogenesis, and peritoneal dissemination

28 September 2017

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Angiotensin II activates MAP kinase and NF-kappaB through angiotensin II type I receptor in human pancreatic cancer cells.

28 September 2017

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Identification and validation of an ERBB2 gene expression signature in breast cancers

28 September 2017

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Angiotensin II receptor antagonists: an emerging new class of cardiovascular therapeutics

28 September 2017

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p185HER2 monoclonal antibody has antiproliferative effects in vitro and sensitizes human breast tumor cells to tumor necrosis factor

28 September 2017

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Amplification of a novel v-erbB-related gene in a human mammary carcinoma

28 September 2017

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erbB-2 is a potent oncogene when overexpressed in NIH/3T3 cells

30 May 2018

1 reference

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PKC-zeta is required for angiotensin II-induced activation of ERK and synthesis of C-FOS in MCF-7 cells.

30 May 2018

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Crossref

https://api.crossref.org/works/10.1073/PNAS.0900351106

Pharmacogenomic predictor of sensitivity to preoperative chemotherapy with paclitaxel and fluorouracil, doxorubicin, and cyclophosphamide in breast cancer

21 January 2018

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A cohort study of antihypertensive medication use and breast cancer among Danish women

21 January 2018

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Angiotensin II receptor blocker shows antiproliferative activity in prostate cancer cells: a possibility of tyrosine kinase inhibitor of growth factor

28 November 2018

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Angiotensin II type I antagonist prevents pulmonary metastasis of murine renal cancer by inhibiting tumor angiogenesis

28 November 2018

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Angiotensin-converting enzyme gene insertion/deletion polymorphism and breast cancer risk

28 November 2018

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12 December 2020

Differential roles of Angiotensinogen and Angiotensin Receptor type 1 polymorphisms in breast cancer risk

1 reference

12 December 2020

Estrogen regulates angiotensin AT1 receptor expression via cytosolic proteins that bind to the 5' leader sequence of the receptor mRNA

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12 December 2020

Angiotensin II type 1 receptor expression in human pancreatic cancer and growth inhibition by angiotensin II type 1 receptor antagonist

1 reference

12 December 2020

New amplified and highly expressed genes discovered in the ERBB2 amplicon in breast cancer by cDNA microarrays

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12 December 2020

Identifiers

DOI

10.1073/PNAS.0900351106

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19487683 AND SRC:MED&resulttype=core&format=json

29 January 2020

ADS bibcode

2009PNAS..10610284R

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19487683 AND SRC:MED&resulttype=core&format=json

29 January 2020

PubMed publication ID

19487683

2 references