Identification of the transcriptional targets of FOXP2, a gene linked to speech and language, in developing human brain (Q24648621)

7

0 references

Genevieve Konopka

object named as

Genevieve Konopka

2

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Simon Fisher

object named as

Simon E Fisher

8

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author name string

Elizabeth Spiteri

1

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Giovanni Coppola

3

0 references

Jamee Bomar

4

0 references

Michael Oldham

5

0 references

Jing Ou

6

0 references

Bing Ren

American Journal of Human Genetics

9

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language of work or name

English

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publication date

December 2007

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published in

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volume

81

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issue

6

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page(s)

1144-57

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describes a project that uses

limma

1 reference

Europe PubMed Central

22 June 2022

https://europepmc.org/article/PMC/2276350

inferred from PubMed Central ID database lookup

cites work

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7 April 2017

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7 April 2017

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7 April 2017

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Direct control of the Forkhead transcription factor AFX by protein kinase B

7 April 2017

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7 April 2017

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Mutations in the kinase Rsk-2 associated with Coffin-Lowry syndrome

7 April 2017

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Molecular evolution of FOXP2, a gene involved in speech and language

7 April 2017

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7 April 2017

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Integration of Smad and forkhead pathways in the control of neuroepithelial and glioblastoma cell proliferation

7 April 2017

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7 April 2017

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Parallel patterns of evolution in the genomes and transcriptomes of humans and chimpanzees

7 April 2017

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The Semaphorin 4D receptor Plexin-B1 is a GTPase activating protein for R-Ras

7 April 2017

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Bilateral brain abnormalities associated with dominantly inherited verbal and orofacial dyspraxia

7 April 2017

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A forkhead-domain gene is mutated in a severe speech and language disorder

7 April 2017

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Neocortex patterning by the secreted signaling molecule FGF8

7 April 2017

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Disruption of two novel genes by a translocation co-segregating with schizophrenia

7 April 2017

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The winged-helix/forkhead protein myocyte nuclear factor beta (MNF-beta) forms a co-repressor complex with mammalian sin3B

7 April 2017

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Smad2 and Smad3 positively and negatively regulate TGF beta-dependent transcription through the forkhead DNA-binding protein FAST2

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Characterization of a new subfamily of winged-helix/forkhead (Fox) genes that are expressed in the lung and act as transcriptional repressors

7 April 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

The Wnt-1 (int-1) proto-oncogene is required for development of a large region of the mouse brain

7 April 2017

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Targeted disruption of the murine int-1 proto-oncogene resulting in severe abnormalities in midbrain and cerebellar development

7 April 2017

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A global map of p53 transcription-factor binding sites in the human genome

7 April 2017

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Accelerated evolution of nervous system genes in the origin of Homo sapiens

7 April 2017

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Parallel FoxP1 and FoxP2 expression in songbird and human brain predicts functional interaction

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

A gene expression atlas of the central nervous system based on bacterial artificial chromosomes

7 April 2017

1 reference

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Elevated gene expression levels distinguish human from non-human primate brains

7 April 2017

1 reference

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Intra- and interspecific variation in primate gene expression patterns

7 April 2017

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Molecular evidence for increased expression of genes related to immune and chaperone function in the prefrontal cortex in schizophrenia.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Genome-wide analysis of Foxp3 target genes in developing and mature regulatory T cells.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Conservation and evolution of gene coexpression networks in human and chimpanzee brains

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Mice deficient for galanin receptor 2 have decreased neurite outgrowth from adult sensory neurons and impaired pain-like behaviour

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Functional genetic analysis of mutations implicated in a human speech and language disorder

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Disrupted in schizophrenia 1: building brains and memories

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Association between FOXP2 polymorphisms and schizophrenia with auditory hallucinations.

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

T-bet binding to newly identified target gene promoters is cell type-independent but results in variable context-dependent functional effects

28 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Deconstructing language by comparative gene expression: from neurobiology to microarray

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

A neuronal nitric oxide synthase (NOS-I) haplotype associated with schizophrenia modifies prefrontal cortex function.

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Moving primate genomics beyond the chimpanzee genome

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Genome-wide analysis of cAMP-response element binding protein occupancy, phosphorylation, and target gene activation in human tissues

28 September 2017

1 reference

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Human brain evolution: insights from microarrays

28 September 2017

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Regional patterns of gene expression in human and chimpanzee brains

28 September 2017

1 reference

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28 September 2017

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Multiple Domains Define the Expression and Regulatory Properties of Foxp1 Forkhead Transcriptional Repressors

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Accelerated protein evolution and origins of human-specific features: Foxp2 as an example

28 September 2017

1 reference

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D2 dopamine receptor gene in psychiatric and neurologic disorders and its phenotypes

28 September 2017

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Expression analysis of RSK gene family members: the RSK2 gene, mutated in Coffin-Lowry syndrome, is prominently expressed in brain structures essential for cognitive function and learning

28 September 2017

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Allelic association of the neuronal nitric oxide synthase (NOS1) gene with schizophrenia

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Amino acid replacement is rapid in primates for the mature polypeptides of COX subunits, but not for their targeting presequences

28 September 2017

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Behavioural analysis of an inherited speech and language disorder: comparison with acquired aphasia.

28 September 2017

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Heritability of lobar brain volumes in twins supports genetic models of cerebral laterality and handedness

28 September 2017

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Association of ZNF74 gene genotypes with age-at-onset of schizophrenia

28 September 2017

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Increased CNS levels of apolipoprotein D in schizophrenic and bipolar subjects: implications for the pathophysiology of psychiatric disorders

28 September 2017

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Novel polymorphisms of the human cholecystokinin A receptor gene: an association analysis with schizophrenia

28 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Right-Left Asymmetries in the Brain

28 September 2017

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FOXP2 expression during brain development coincides with adult sites of pathology in a severe speech and language disorder

28 September 2017

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FOXP2 in focus: what can genes tell us about speech and language?

30 May 2018

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Regulation of neurite outgrowth by integrin activation.

30 May 2018

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Increased expression of Wnt-1 in schizophrenic brains

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Increased numbers of CD5 B lymphocytes in schizophrenic patients.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Association between CCK-AR gene and schizophrenia with auditory hallucinations.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Positive association of the Disrupted-in-Schizophrenia-1 gene (DISC1) with schizophrenia in the Chinese Han population.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Towards understanding the schizophrenia code: an expanded convergent functional genomics approach

28 November 2018

1 reference

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Association study of eight circadian genes with bipolar I disorder, schizoaffective disorder and schizophrenia

28 November 2018

1 reference

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Cell adhesion molecules regulate Ca2 -mediated steering of growth cones via cyclic AMP and ryanodine receptor type 3.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

β-Catenin activates the growth factor endothelin-1 in colon cancer cells

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Accelerated evolution of the electron transport chain in anthropoid primates.

28 November 2018

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A possible association between the CCK-AR gene and persistent auditory hallucinations in schizophrenia.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

FOXP2 and the mirror system.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Expression of the kynurenine pathway enzyme tryptophan 2,3-dioxygenase is increased in the frontal cortex of individuals with schizophrenia

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Association between schizophrenia with ocular misalignment and polyalanine length variation in PMX2B.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Characterization of Foxp2 and Foxp1 mRNA and protein in the developing and mature brain.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Initiating Hox gene expression: in the early chick neural tube differential sensitivity to FGF and RA signaling subdivides the HoxB genes in two distinct groups.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Possible association of a cholecystokinin promoter variant to schizophrenia.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

foxD5a, a Xenopus winged helix gene, maintains an immature neural ectoderm via transcriptional repression that is dependent on the C-terminal domain.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Expression pattern of PAX3 and PAX6 genes during human embryogenesis.

28 November 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2276350

Hox gene expression reveals regionalization along the anteroposterior axis of the zebrafish notochord.

28 November 2018

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Elevation of CD5 B lymphocytes in schizophrenia

28 November 2018

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12 December 2020

The thyroid transcription factor 2 (TTF-2) is a promoter-specific DNA-binding independent transcriptional repressor

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12 December 2020

Sly FOXP2: genomic conflict in the evolution of language

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12 December 2020

Association study between the cholecystokinin A receptor gene and schizophrenia in the Japanese population

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Alterations in GABA-related transcriptome in the dorsolateral prefrontal cortex of subjects with schizophrenia

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Identifiers

DOI

10.1086/522237

1 reference

1 reference

1 reference

PubMed publication ID

17999357

1 reference