Agonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivo (Q24647416)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18195357 AND SRC:MED&resulttype=core&format=json

1 January 2020

title

Agonist-directed signaling of the serotonin 2A receptor depends on beta-arrestin-2 interactions in vivo (English)

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1 January 2020

0 references

3

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1 January 2020

author name string

Cullen L Schmid

series ordinal

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18195357 AND SRC:MED&resulttype=core&format=json

1 January 2020

Kirsten M Raehal

series ordinal

2

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1 January 2020

language of work or name

English

0 references

publication date

14 January 2008

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18195357 AND SRC:MED&resulttype=core&format=json

Proceedings of the National Academy of Sciences of the United States of America

1 January 2020

number of pages

6

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based on heuristic

inferred from page(s)

published in

1 reference

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1 January 2020

volume

105

1 reference

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1 January 2020

issue

3

1 reference

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1 January 2020

page(s)

1079-1084

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18195357 AND SRC:MED&resulttype=core&format=json

An Akt/beta-arrestin 2/PP2A signaling complex mediates dopaminergic neurotransmission and behavior

1 January 2020

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7 April 2017

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Functional Selectivity and Classical Concepts of Quantitative Pharmacology

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Hallucinogens recruit specific cortical 5-HT(2A) receptor-mediated signaling pathways to affect behavior

7 April 2017

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1-Aminomethylbenzocycloalkanes: conformationally restricted hallucinogenic phenethylamine analogues as functionally selective 5-HT2A receptor agonists

7 April 2017

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Caveolin-1 interacts with 5-HT2A serotonin receptors and profoundly modulates the signaling of selected Galphaq-coupled protein receptors

7 April 2017

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Acid-sensing ion channel 2 (ASIC2) modulates ASIC1 H -activated currents in hippocampal neurons

7 April 2017

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Dopaminergic supersensitivity in G protein-coupled receptor kinase 6-deficient mice

7 April 2017

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Paradoxical trafficking and regulation of 5-HT(2A) receptors by agonists and antagonists

7 April 2017

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beta-Arrestin 1 and 2 differentially regulate heptahelical receptor signaling and trafficking

7 April 2017

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Enhanced morphine analgesia in mice lacking beta-arrestin 2

7 April 2017

2 references

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7 April 2017

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7 January 2021

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A possible correlation between drug-induced hallucinations in man and a behavioural response in mice

1 reference

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Spinophilin blocks arrestin actions in vitro and in vivo at G protein-coupled receptors

7 April 2017

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Beta-arrestin-biased ligands at seven-transmembrane receptors

7 April 2017

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An opioid agonist that does not induce mu-opioid receptor--arrestin interactions or receptor internalization

27 September 2017

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Desensitization of G protein-coupled receptors and neuronal functions

27 September 2017

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G protein-coupled receptor kinase/beta-arrestin systems and drugs of abuse: psychostimulant and opiate studies in knockout mice.

27 September 2017

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The PDZ-binding domain is essential for the dendritic targeting of 5-HT2A serotonin receptors in cortical pyramidal neurons in vitro.

27 September 2017

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No hypothermic response to serotonin in 5-HT7 receptor knockout mice

27 September 2017

1 reference

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Classical and new roles of beta-arrestins in the regulation of G-protein-coupled receptors

27 September 2017

1 reference

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Clozapine and other 5-hydroxytryptamine-2A receptor antagonists alter the subcellular distribution of 5-hydroxytryptamine-2A receptors in vitro and in vivo

27 September 2017

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Structure and function of the third intracellular loop of the 5-hydroxytryptamine2A receptor: the third intracellular loop is alpha-helical and binds purified arrestins

27 September 2017

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Serotonergic antagonist effects on trafficking of serotonin 5-HT2A receptors in vitro and in vivo

27 September 2017

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Rapid agonist-induced internalization of the 5-hydroxytryptamine2A receptor occurs via the endosome pathway in vitro

27 September 2017

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A complex signaling cascade links the serotonin2A receptor to phospholipase A2 activation: the involvement of MAP kinases

27 September 2017

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The interaction of a constitutively active arrestin with the arrestin-insensitive 5-HT(2A) receptor induces agonist-independent internalization

30 May 2018

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Differential mechanisms of morphine antinociceptive tolerance revealed in (beta)arrestin-2 knock-out mice.

30 May 2018

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Discriminative stimulus properties of the serotonergic agent 1-(2,5-dimethoxy-4-iodophenyl)-2-aminopropane (DOI).

30 May 2018

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Morphine side effects in beta-arrestin 2 knockout mice

30 May 2018

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5-HT(2A) receptors: location and functional analysis in intestines of wild-type and 5-HT(2A) knockout mice

21 January 2018

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Activity-dependent mRNA splicing controls ER export and synaptic delivery of NMDA receptors

21 January 2018

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Relative opioid efficacy is determined by the complements of the G protein-coupled receptor desensitization machinery

21 January 2018

1 reference

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Cell-type specific effects of endocytosis inhibitors on 5-hydroxytryptamine(2A) receptor desensitization and resensitization reveal an arrestin-, GRK2-, and GRK5-independent mode of regulation in human embryonic kidney 293 cells

21 January 2018

1 reference

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Characterization of the 5-HT2 receptor antagonist MDL 100907 as a putative atypical antipsychotic: behavioral, electrophysiological and neurochemical studies.

28 November 2018

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Muscarinic Supersensitivity and Impaired Receptor Desensitization in G Protein–Coupled Receptor Kinase 5–Deficient Mice

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18195357

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.0708862105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18195357 AND SRC:MED&resulttype=core&format=json

1 January 2020

0 references

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18195357 AND SRC:MED&resulttype=core&format=json

1 January 2020

PubMed publication ID

18195357

1 reference