Bile acid transporters in health and disease (Q24647024)

Membrane topology of human ASBT (SLC10A2) determined by dual label epitope insertion scanning mutagenesis. New evidence for seven transmembrane domains

Europe PubMed Central

title

Bile acid transporters in health and disease (English)

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author name string

A Kosters

series ordinal

1

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S J Karpen

series ordinal

2

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language of work or name

English

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publication date

July 2008

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published in

Xenobiotica

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volume

38

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issue

7-8

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page(s)

1043-71

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cites work

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OSTalpha-OSTbeta: a major basolateral bile acid and steroid transporter in human intestinal, renal, and biliary epithelia

7 April 2017

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The heteromeric organic solute transporter alpha-beta, Ostalpha-Ostbeta, is an ileal basolateral bile acid transporter

7 April 2017

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Functional Complementation between a Novel Mammalian Polygenic Transport Complex and an Evolutionarily Ancient Organic Solute Transporter, OSTα-OSTβ

7 April 2017

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Vitamin D receptor as an intestinal bile acid sensor

7 April 2017

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Bile acids: natural ligands for an orphan nuclear receptor

7 April 2017

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Identification of a nuclear receptor for bile acids

7 April 2017

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A gene encoding a liver-specific ABC transporter is mutated in progressive familial intrahepatic cholestasis

7 April 2017

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Primary bile acid malabsorption caused by mutations in the ileal sodium-dependent bile acid transporter gene (SLC10A2)

7 April 2017

1 reference

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Molecular cloning, chromosomal localization, and functional characterization of a human liver Na /bile acid cotransporter

7 April 2017

1 reference

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Identification of a Mutation in the Ileal Sodium-dependent Bile Acid Transporter Gene That Abolishes Transport Activity

7 April 2017

1 reference

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Functional expression cloning and characterization of the hepatocyte Na /bile acid cotransport system

7 April 2017

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Bile acid transporters: structure, function, regulation and pathophysiological implications

7 April 2017

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Ligand-dependent activation of the farnesoid X-receptor directs arginine methylation of histone H3 by CARM1

7 April 2017

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Differential regulation of bile acid homeostasis by the farnesoid X receptor in liver and intestine

7 April 2017

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Heterodimerization, trafficking and membrane topology of the two proteins, Ost alpha and Ost beta, that constitute the organic solute and steroid transporter

7 April 2017

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Protein-protein interactions and membrane localization of the human organic solute transporter

7 April 2017

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International Union of Pharmacology. LXII. The NR1H and NR1I receptors: constitutive androstane receptor, pregnene X receptor, farnesoid X receptor alpha, farnesoid X receptor beta, liver X receptor alpha, liver X receptor beta, and vitamin D recept

7 April 2017

1 reference

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The bile salt export pump

7 April 2017

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Upregulation of a basolateral FXR-dependent bile acid efflux transporter OSTalpha-OSTbeta in cholestasis in humans and rodents

7 April 2017

1 reference

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The nuclear receptor for bile acids, FXR, transactivates human organic solute transporter-alpha and -beta genes

7 April 2017

1 reference

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Impaired expression and function of the bile salt export pump due to three novel ABCB11 mutations in intrahepatic cholestasis

7 April 2017

1 reference

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Principles for modulation of the nuclear receptor superfamily

7 April 2017

1 reference

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Degradation of the apical sodium-dependent bile acid transporter by the ubiquitin-proteasome pathway in cholangiocytes

7 April 2017

1 reference

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Benign recurrent intrahepatic cholestasis type 2 is caused by mutations in ABCB11

7 April 2017

1 reference

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Bile acid-induced negative feedback regulation of the human ileal bile acid transporter

7 April 2017

1 reference

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Organic anion transporting polypeptides of the OATP/ SLC21 family: phylogenetic classification as OATP/ SLCO superfamily, new nomenclature and molecular/functional properties

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

The sodium bile salt cotransport family SLC10

7 April 2017

1 reference

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Liver receptor homologue-1 mediates species- and cell line-specific bile acid-dependent negative feedback regulation of the apical sodium-dependent bile acid transporter

7 April 2017

1 reference

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Functional expression of the canalicular bile salt export pump of human liver

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Human apical sodium-dependent bile salt transporter gene (SLC10A2) is regulated by the peroxisome proliferator-activated receptor alpha

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Hepatocyte nuclear factor-1alpha is an essential regulator of bile acid and plasma cholesterol metabolism

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Divergent homeobox gene hex regulates promoter of the Na( )-dependent bile acid cotransporter

7 April 2017

1 reference

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Drug- and estrogen-induced cholestasis through inhibition of the hepatocellular bile salt export pump (Bsep) of rat liver

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Cloning and expression of murine sister of P-glycoprotein reveals a more discriminating transporter than MDR1/P-glycoprotein

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

The continuing importance of bile acids in liver and intestinal disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Hepatocanalicular bile salt export pump deficiency in patients with progressive familial intrahepatic cholestasis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Modulation by drugs of human hepatic sodium-dependent bile acid transporter (sodium taurocholate cotransporting polypeptide) activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Targeted disruption of the microsomal epoxide hydrolase gene. Microsomal epoxide hydrolase is required for the carcinogenic activity of 7,12-dimethylbenz[a]anthracene

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Endogenous bile acids are ligands for the nuclear receptor FXR/BAR

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Expression and transport properties of the human ileal and renal sodium-dependent bile acid transporter

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Localization of the ileal sodium-bile acid cotransporter gene (SLC10A2) to human chromosome 13q33

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Radixin is required to maintain apical canalicular membrane structure and function in rat hepatocytes

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Transactivation of rat apical sodium-dependent bile acid transporter and increased bile acid transport by 1alpha,25-dihydroxyvitamin D3 via the vitamin D receptor

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Trafficking of the bile salt export pump from the Golgi to the canalicular membrane is regulated by the p38 MAP kinase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Enterohepatic bile salt transporters in normal physiology and liver disease

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

The human bile salt export pump: characterization of substrate specificity and identification of inhibitors

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

The role of bile salt export pump mutations in progressive familial intrahepatic cholestasis type II

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

The role of AP-1 in the transcriptional regulation of the rat apical sodium-dependent bile acid transporter

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Hepatocyte nuclear factor 4alpha (nuclear receptor 2A1) is essential for maintenance of hepatic gene expression and lipid homeostasis

7 April 2017

1 reference

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Newly synthesized canalicular ABC transporters are directly targeted from the Golgi to the hepatocyte apical domain in rat liver

7 April 2017

1 reference

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The Sister of P-glycoprotein Represents the Canalicular Bile Salt Export Pump of Mammalian Liver

7 April 2017

1 reference

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Comparative analysis of the ontogeny of a sodium-dependent bile acid transporter in rat kidney and ileum

7 April 2017

1 reference

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Molecular cloning, tissue distribution, and expression of a 14-kDa bile acid-binding protein from rat ileal cytosol

7 April 2017

1 reference

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Fibroblast growth factor 15 functions as an enterohepatic signal to regulate bile acid homeostasis

7 April 2017

1 reference

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Effects of bile acids on expression of the human apical sodium dependent bile acid transporter gene

7 April 2017

1 reference

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Phenotypic differences in PFIC2 and BRIC2 correlate with protein stability of mutant Bsep and impaired taurocholate secretion in MDCK II cells

27 September 2017

1 reference

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Compromised intestinal lipid absorption in mice with a liver-specific deficiency of liver receptor homolog 1.

27 September 2017

1 reference

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Regulation of hepatic bile acid transporters Ntcp and Bsep expression

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Levels of plasma membrane expression in progressive and benign mutations of the bile salt export pump (Bsep/Abcb11) correlate with severity of cholestatic diseases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Fasting induces basolateral uptake transporters of the SLC family in the liver via HNF4alpha and PGC1alpha

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

The expression of the solute carriers NTCP and OCT-1 is regulated by cholesterol in HepG2 cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Role of STAT5a in regulation of sex-specific gene expression in female but not male mouse liver revealed by microarray analysis.

27 September 2017

1 reference

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Biliary secretion and excretion in health and disease: current concepts

27 September 2017

1 reference

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Principles of hepatic organic anion transporter regulation during cholestasis, inflammation and liver regeneration

27 September 2017

1 reference

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Cholestasis during pregnancy: rare hepatic diseases unmasked by pregnancy.

27 September 2017

1 reference

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Mechanisms of disease: mechanisms and clinical implications of cholestasis in sepsis.

27 September 2017

1 reference

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Hepatobiliary transporters and drug-induced cholestasis

27 September 2017

1 reference

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Bile salt excretory pump: biology and pathobiology

27 September 2017

1 reference

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Genetic variability, haplotype structures, and ethnic diversity of hepatic transporters MDR3 (ABCB4) and bile salt export pump (ABCB11).

27 September 2017

1 reference

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Role of nuclear receptors in the adaptive response to bile acids and cholestasis: pathogenetic and therapeutic considerations.

27 September 2017

1 reference

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Estrogen receptor alpha mediates 17alpha-ethynylestradiol causing hepatotoxicity

27 September 2017

1 reference

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The solute carrier family SLC10: more than a family of bile acid transporters regarding function and phylogenetic relationships.

27 September 2017

1 reference

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Hepatocanalicular transport defects: pathophysiologic mechanisms of rare diseases

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Cholesterol dependent downregulation of mouse and human apical sodium dependent bile acid transporter (ASBT) gene expression: molecular mechanism and physiological consequences.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Regulation of the mouse organic solute transporter alpha-beta, Ostalpha-Ostbeta, by bile acids

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Topography of the membrane domain of the liver Na -dependent bile acid transporter

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Discovery of potent, nonsystemic apical sodium-codependent bile acid transporter inhibitors (Part 2).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

The human Na -taurocholate cotransporting polypeptide gene is activated by glucocorticoid receptor and peroxisome proliferator-activated receptor-gamma coactivator-1alpha, and suppressed by bile acids via a small heterodimer partner-dependent mechan

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Retinoid x receptor heterodimers in the metabolic syndrome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Dephosphorylation of Ser-226 facilitates plasma membrane retention of Ntcp

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Enterohepatic transport of bile salts and genetics of cholestasis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Regulation of hepatic metabolic pathways by the orphan nuclear receptor SHP.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

The methyl transferase PRMT1 functions as co-activator of farnesoid X receptor (FXR)/9-cis retinoid X receptor and regulates transcription of FXR responsive genes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Two common PFIC2 mutations are associated with the impaired membrane trafficking of BSEP/ABCB11.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Cholesterol modulates human intestinal sodium-dependent bile acid transporter

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Cellular regulation of hepatic bile acid transport in health and cholestasis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Role of liver-enriched transcription factors and nuclear receptors in regulating the human, mouse, and rat NTCP gene

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Human ileal bile acid transporter gene ASBT (SLC10A2) is transactivated by the glucocorticoid receptor

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Ca2 -dependent protein kinase C isoforms induce cholestasis in rat liver

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

A progressive familial intrahepatic cholestasis type 2 mutation causes an unstable, temperature-sensitive bile salt export pump.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Ethnicity-dependent polymorphism in Na -taurocholate cotransporting polypeptide (SLC10A1) reveals a domain critical for bile acid substrate recognition

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Cell surface expression and bile acid transport function of one topological form of m-epoxide hydrolase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Inhibition of human m-epoxide hydrolase gene expression in a case of hypercholanemia

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Complex inheritance of familial hypercholanemia with associated mutations in TJP2 and BAAT.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Bile salt transporters: molecular characterization, function, and regulation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Retinoid X receptor (RXR) agonist-induced antagonism of farnesoid X receptor (FXR) activity due to absence of coactivator recruitment and decreased DNA binding

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Inflammatory-mediated repression of the rat ileal sodium-dependent bile acid transporter by c-fos nuclear translocation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

A 14-amino acid sequence with a beta-turn structure is required for apical membrane sorting of the rat ileal bile acid transporter

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Loss of nuclear receptor SHP impairs but does not eliminate negative feedback regulation of bile acid synthesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Nuclear receptor regulation of hepatic function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Organization of the membrane domain of the human liver sodium/bile acid cotransporter

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Three hundred twenty-six genetic variations in genes encoding nine members of ATP-binding cassette, subfamily B (ABCB/MDR/TAP), in the Japanese population

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

27 September 2017

Bile salt transporters

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Expression cloning of two genes that together mediate organic solute and steroid transport in the liver of a marine vertebrate

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Characterization of the mouse bile salt export pump overexpressed in the baculovirus system

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Regulation of the dynamic localization of the rat Bsep gene-encoded bile salt export pump by anisoosmolarity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Targeted inactivation of sister of P-glycoprotein gene (spgp) in mice results in nonprogressive but persistent intrahepatic cholestasis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Transporters on demand: intrahepatic pools of canalicular ATP binding cassette transporters in rat liver

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

The rat liver Na( )/bile acid cotransporter. Importance of the cytoplasmic tail to function and plasma membrane targeting

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Hepatic transport of bile salts

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Structural and functional characterization of liver cell-specific activity of the human sodium/taurocholate cotransporter

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Elevated levels of hepatocyte nuclear factor 3beta in mouse hepatocytes influence expression of genes involved in bile acid and glucose homeostasis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Intracellular transport of bile acids

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Molecular cloning and characterization of the murine bile salt export pump

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Substrate specificity of the ileal and the hepatic Na( )/bile acid cotransporters of the rabbit. II. A reliable 3D QSAR pharmacophore model for the ileal Na( )/bile acid cotransporter

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Substrate specificity of the ileal and the hepatic Na( )/bile acid cotransporters of the rabbit. I. Transport studies with membrane vesicles and cell lines expressing the cloned transporters

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Signal transduction and hepatocellular bile acid transport: cross talk between bile acids and second messengers

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Phosphoinositide 3-kinase lipid products regulate ATP-dependent transport by sister of P-glycoprotein and multidrug resistance associated protein 2 in bile canalicular membrane vesicles

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Molecular cloning and functional characterization of two alternatively spliced Ntcp isoforms from mouse liver1.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Sorting of rat liver and ileal sodium-dependent bile acid transporters in polarized epithelial cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Electrogenicity of Na( )-coupled bile acid transporters

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Endotoxin downregulates rat hepatic ntcp gene expression via decreased activity of critical transcription factors

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Substrate specificity of sinusoidal bile acid and organic anion uptake systems in rat and human liver

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Rat cholangiocytes absorb bile acids at their apical domain via the ileal sodium-dependent bile acid transporter

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Regulation of the rat liver sodium-dependent bile acid cotransporter gene by prolactin. Mediation of transcriptional activation by Stat5.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Bile acid transport systems as pharmaceutical targets

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Sinusoidal (basolateral) bile salt uptake systems of hepatocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Molecular mechanisms of hepatic bile salt transport from sinusoidal blood into bile

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Specific inhibitors of ileal bile acid transport

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

The mouse ileal lipid-binding protein gene: a model for studying axial patterning during gut morphogenesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Bile acid metabolism: relationship of bile acid malabsorption and diarrhea.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Active and passive bile acid absorption in man. Perfusion studies of the ileum and jejunum

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Sodium-dependent taurocholate uptake by isolated rat hepatocytes occurs through an electrogenic mechanism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

LXR alpha transactivates mouse organic solute transporter alpha and beta via IR-1 elements shared with FXR.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Impaired localisation and transport function of canalicular Bsep in taurolithocholate induced cholestasis in the rat.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Substrate specificities of rat oatp1 and ntcp: implications for hepatic organic anion uptake

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Role of PP2B in cAMP-induced dephosphorylation and translocation of NTCP.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Short-term regulation of bile acid uptake by microfilament-dependent translocation of rat ntcp to the plasma membrane

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Role of protein phosphatases in cyclic AMP-mediated stimulation of hepatic Na /taurocholate cotransport

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Taxol resistance mediated by transfection of the liver-specific sister gene of P-glycoprotein

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

cAMP increases liver Na -taurocholate cotransport by translocating transporter to plasma membranes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Molecular Properties of Hepatic Uptake Systems for Bile Acids and Organic Anions

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Chlorambucil-taurocholate is transported by bile acid carriers expressed in human hepatocellular carcinomas

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Effect of antisense oligonucleotides on the expression of hepatocellular bile acid and organic anion uptake systems in Xenopus laevis oocytes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

The functional expression of sodium-dependent bile acid transport in Madin-Darby canine kidney cells transfected with the cDNA for microsomal epoxide hydrolase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Cholestasis caused by inhibition of the adenosine triphosphate-dependent bile salt transport in rat liver

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Characterization of cloned rat liver Na( )-bile acid cotransporter using peptide and fusion protein antibodies

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Effect of microsomal enzyme inducers on the biliary excretion of cardiac glycosides.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Proceedings: Increased cholesterol saturation in rat bile induced by spironolactone and pregnenolone-16alpha-carbonitrile.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Expression of the hepatocyte Na /bile acid cotransporter in Xenopus laevis oocytes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Characterization of the passive and active transport mechanisms for bile acid uptake into rat isolated intestinal epithelial cells

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Effect of Na on bile acid uptake by isolated rat hepatocytes. Evidence for a heterogeneous system

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Secretin activation of the apical Na -dependent bile acid transporter is associated with cholehepatic shunting in rats

30 May 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Vesicle targeting to the apical domain regulates bile excretory function in isolated rat hepatocyte couplets.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Sex-dependent liver gene expression is extensive and largely dependent upon signal transducer and activator of transcription 5b (STAT5b): STAT5b-dependent activation of male genes and repression of female genes revealed by microarray analysis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Preventive effect of silymarin against taurolithocholate-induced cholestasis in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Targeted deletion of the ileal bile acid transporter eliminates enterohepatic cycling of bile acids in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

The orphan nuclear receptor, shp, mediates bile acid-induced inhibition of the rat bile acid transporter, ntcp

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

The endothelin antagonist bosentan inhibits the canalicular bile salt export pump: a potential mechanism for hepatic adverse reactions

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Hepatic overexpression of murine Abcb11 increases hepatobiliary lipid secretion and reduces hepatic steatosis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Troglitazone-induced intrahepatic cholestasis by an interference with the hepatobiliary export of bile acids in male and female rats. Correlation with the gender difference in troglitazone sulfate formation and the inhibition of the canalicular bile

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Functional analysis of the rat bile salt export pump gene promoter

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Hepatocyte nuclear factor 1 alpha: a key mediator of the effect of bile acids on gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Transporter-mediated bile acid uptake causes Ca2 -dependent cell death in rat pancreatic acinar cells

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Degradation of the sodium taurocholate cotransporting polypeptide (NTCP) by the ubiquitin-proteasome system

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

A novel class of apical sodium-dependent bile acid transporter inhibitors: the amphiphilic 4-oxo-1-phenyl-1,4-dihydroquinoline derivatives

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Expression of the bile salt export pump is maintained after chronic cholestasis in the rat.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

FXR-activating ligands inhibit rabbit ASBT expression via FXR-SHP-FTF cascade

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Interindividual variability of canalicular ATP-binding-cassette (ABC)-transporter expression in human liver.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Mechanisms by which cAMP increases bile acid secretion in rat liver and canalicular membrane vesicles

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

c-Fos is a critical mediator of inflammatory-mediated repression of the apical sodium-dependent bile acid transporter.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

BSEP and MDR3 haplotype structure in healthy Caucasians, primary biliary cirrhosis and primary sclerosing cholangitis

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Sequence analysis of bile salt export pump (ABCB11) and multidrug resistance p-glycoprotein 3 (ABCB4, MDR3) in patients with intrahepatic cholestasis of pregnancy

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Multihormonal regulation of hepatic sinusoidal Ntcp gene expression

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Targeted disruption of the nuclear receptor FXR/BAR impairs bile acid and lipid homeostasis.

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

The involvement of the pregnane X receptor in hepatic gene regulation during inflammation in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Redundant pathways for negative feedback regulation of bile acid production

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Severe cholestasis induced by cholic acid feeding in knockout mice of sister of P-glycoprotein

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

1-[4-[4[(4R,5R)-3,3-Dibutyl-7-(dimethylamino)-2,3,4,5-tetrahydro-4-hydroxy-1,1-dioxido-1-benzothiepin-5-yl]phenoxy]butyl]-4-aza-1-azoniabicyclo[2.2.2]octane methanesulfonate (SC-435), an ileal apical sodium-codependent bile acid transporter inhibito

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Effects of bile salt flux variations on the expression of hepatic bile salt transporters in vivo in mice

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Lithocholic acid decreases expression of bile salt export pump through farnesoid X receptor antagonist activity

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Role of nuclear receptors and hepatocyte-enriched transcription factors for Ntcp repression in biliary obstruction in mouse liver

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Coordinated induction of bile acid detoxification and alternative elimination in mice: role of FXR-regulated organic solute transporter-alpha/beta in the adaptive response to bile acids

21 January 2018

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

Ileal bile acid transporter inhibition, CYP7A1 induction, and antilipemic action of 264W94.

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Role of the PI3K/PKB signaling pathway in cAMP-mediated translocation of rat liver Ntcp

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Expression cloning and characterization of the hamster ileal sodium-dependent bile acid transporter.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Identification of a sister gene to P-glycoprotein

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2823065

Diarrhoea associated with idiopathic bile acid malabsorption. Fact or fantasy?

28 November 2018

1 reference

12 December 2020

Primary bile acid malabsorption: defective in vitro ileal active bile acid transport

1 reference

12 December 2020

Bile acid transport in cultured rat hepatocytes

1 reference

12 December 2020

Jejunum is more important than terminal ileum for taurocholate absorption in rats

1 reference

12 December 2020

Mutations and polymorphisms in the bile salt export pump and the multidrug resistance protein 3 associated with drug-induced liver injury

1 reference

12 December 2020

A novel class of apical sodium co-dependent bile acid transporter inhibitors: the 2,3-disubstituted-4-phenylquinolines

1 reference

12 December 2020

Assignment of a rat liver Na /bile acid cotransporter gene to chromosome 6q24.

1 reference

12 December 2020

Protein kinase signaling pathway triggered by cell swelling and involved in the activation of glycogen synthase and acetyl-CoA carboxylase in isolated rat hepatocytes

1 reference

12 December 2020

Regulation and translocation of ATP-dependent apical membrane proteins in rat liver

1 reference

12 December 2020

The effect of dibutyryl cyclic AMP on the uptake of taurocholic acid by isolated rat liver cells

1 reference

12 December 2020

Conformational change in plasma albumin due to interaction with isolated rat hepatocyte

1 reference

12 December 2020

DBcAMP stimulates vesicle transport and HRP excretion in isolated perfused rat liver

1 reference

12 December 2020

Role of intracellular calcium and protein kinases in the activation of hepatic Na /taurocholate cotransport by cyclic AMP

1 reference

12 December 2020

Combined mutations of canalicular transporter proteins cause severe intrahepatic cholestasis of pregnancy

1 reference

12 December 2020

Glucocorticoids upregulate taurocholate transport by ileal brush-border membrane

1 reference

12 December 2020

Functional expression of the apical Na -dependent bile acid transporter in large but not small rat cholangiocytes

1 reference

12 December 2020

Neither intestinal sequestration of bile acids nor common bile duct ligation modulate the expression and function of the rat ileal bile acid transporter

1 reference

12 December 2020

The role of phosphoinositide 3-kinase in taurocholate-induced trafficking of ATP-dependent canalicular transporters in rat liver

1 reference

12 December 2020

Sodium taurocholate cotransporting polypeptide is a serine, threonine phosphoprotein and is dephosphorylated by cyclic adenosine monophosphate

1 reference

12 December 2020

Bile acid uptake via the human apical sodium-bile acid cotransporter is electrogenic

1 reference

12 December 2020

Cell swelling-induced translocation of rat liver Na( )/taurocholate cotransport polypeptide is mediated via the phosphoinositide 3-kinase signaling pathway

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12 December 2020

The unique nature of the pediatric liver

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12 December 2020

Heat induces intracellular acidification in human A-431 cells: role of Na( )-H exchange and metabolism

1 reference

https://api.crossref.org/works/10.1080/00498250802040584

7 January 2021