Positive modulation of GABA(B) receptors decreased nicotine self-administration and counteracted nicotine-induced enhancement of brain reward function in rats (Q24647023)

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English	Positive modulation of GABA(B) receptors decreased nicotine self-administration and counteracted nicotine-induced enhancement of brain reward function in rats	scientific article

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6 January 2020

Positive modulation of GABA(B) receptors decreased nicotine self-administration and counteracted nicotine-induced enhancement of brain reward function in rats (English)

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6 January 2020

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Klemens Kaupmann

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6 January 2020

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Neil E Paterson

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6 January 2020

Styliani Vlachou

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6 January 2020

Sebastien Guery

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6 January 2020

Wolfgang Froestl

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6 January 2020

Athina Markou

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29 April 2008

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6 January 2020

Journal of Pharmacology and Experimental Therapeutics

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6 January 2020

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6 January 2020

1

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6 January 2020

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6 January 2020

Syntheses and optimization of new GS39783 analogues as positive allosteric modulators of GABA B receptors

1 reference

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7 April 2017

Positive allosteric modulation of native and recombinant gamma-aminobutyric acid(B) receptors by 2,6-Di-tert-butyl-4-(3-hydroxy-2,2-dimethyl-propyl)-phenol (CGP7930) and its aldehyde analog CGP13501

2 references

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2574924

7 April 2017

https://api.crossref.org/works/10.1124/JPET.108.139204

7 January 2021

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Effects of GABA(B) receptor antagonist, agonists and allosteric positive modulator on the cocaine-induced self-administration and drug discrimination

1 reference

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GABA(B) receptor-positive modulation decreases selective molecular and behavioral effects of cocaine

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The GABA(B) receptor allosteric modulator CGP7930, like baclofen, reduces operant self-administration of ethanol in alcohol-preferring rats

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Reducing effect of the positive allosteric modulators of the GABA(B) receptor, CGP7930 and GS39783, on alcohol intake in alcohol-preferring rats

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Effects of positive allosteric modulators of the GABAB receptor on cocaine self-administration in rats

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N,N'-Dicyclopentyl-2-methylsulfanyl-5-nitro-pyrimidine-4,6-diamine (GS39783) and structurally related compounds: novel allosteric enhancers of gamma-aminobutyric acidB receptor function.

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GABAB receptor-positive modulation-induced blockade of the rewarding properties of nicotine is associated with a reduction in nucleus accumbens DeltaFosB accumulation

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Multiple motivational forces contribute to nicotine dependence.

1 reference

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7 January 2021

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10.1124/JPET.108.139204

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18445779 AND SRC:MED&resulttype=core&format=json

6 January 2020

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Europe PubMed Central

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6 January 2020

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6 January 2020

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