Bcl-XL interacts with Apaf-1 and inhibits Apaf-1-dependent caspase-9 activation (Q24644892)

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M A Benedict

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D Wu

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N Inohara

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

14 April 1998

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published in

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volume

95

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issue

8

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page(s)

4386-91

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cites work

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Cytochrome c and dATP-dependent formation of Apaf-1/caspase-9 complex initiates an apoptotic protease cascade

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Caspases: the executioners of apoptosis

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Apaf-1, a human protein homologous to C. elegans CED-4, participates in cytochrome c-dependent activation of caspase-3

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Interaction of CED-4 with CED-3 and CED-9: a molecular framework for cell death

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Induction of apoptotic program in cell-free extracts: requirement for dATP and cytochrome c

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Involvement of MACH, a novel MORT1/FADD-interacting protease, in Fas/APO-1- and TNF receptor-induced cell death

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bcl-x, a bcl-2-related gene that functions as a dominant regulator of apoptotic cell death

7 April 2017

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Localization of the rap1GAP catalytic domain and sites of phosphorylation by mutational analysis

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Interleukin-3-induced phosphorylation of BAD through the protein kinase Akt

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RAIDD is a new 'death' adaptor molecule

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FLICE, a novel FADD-homologous ICE/CED-3-like protease, is recruited to the CD95 (Fas/APO-1) death--inducing signaling complex

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Caenorhabditis elegans gene ced-9 protects cells from programmed cell death

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The release of cytochrome c from mitochondria: a primary site for Bcl-2 regulation of apoptosis

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CLARP, a death effector domain-containing protein interacts with caspase-8 and regulates apoptosis

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C. elegans cell survival gene ced-9 encodes a functional homolog of the mammalian proto-oncogene bcl-2.

27 September 2017

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Fas-induced activation of the cell death-related protease CPP32 Is inhibited by Bcl-2 and by ICE family protease inhibitors

27 September 2017

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Molecular ordering of the cell death pathway. Bcl-2 and Bcl-xL function upstream of the CED-3-like apoptotic proteases

27 September 2017

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28 November 2018

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Interaction between the C. elegans cell-death regulators CED-9 and CED-4.

28 November 2018

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Cytochrome c-dependent and -independent induction of apoptosis in multiple myeloma cells

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12 December 2020

Programmed cell death in Caenorhabditis elegans

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12 December 2020

Developing Caenorhabditis elegans neurons may contain both cell-death protective and killer activities

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12 December 2020

Controlling cell death

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12 December 2020

Overexpression of Bcl-X(L) inhibits Ara-C-induced mitochondrial loss of cytochrome c and other perturbations that activate the molecular cascade of apoptosis

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12 December 2020