Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum (Q24643310)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18988734 AND SRC:MED&resulttype=core&format=json

25 December 2019

title

Cytosolic chaperones influence the fate of a toxin dislocated from the endoplasmic reticulum (English)

1 reference

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25 December 2019

main subject

endoplasmic reticulum

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0 references

3

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25 December 2019

author name string

Robert A Spooner

1

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25 December 2019

Philip J Hart

2

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25 December 2019

Paola Pietroni

4

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25 December 2019

Christian Rogon

5

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25 December 2019

Jörg Höhfeld

6

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25 December 2019

Lynne M Roberts

7

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25 December 2019

J Michael Lord

8

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25 December 2019

language of work or name

English

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publication date

6 November 2008

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Proceedings of the National Academy of Sciences of the United States of America

25 December 2019

published in

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25 December 2019

volume

105

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25 December 2019

issue

45

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25 December 2019

page(s)

17408-17413

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OS-9 and GRP94 deliver mutant alpha1-antitrypsin to the Hrd1-SEL1L ubiquitin ligase complex for ERAD

25 December 2019

cites work

1 reference

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The cytoplasmic Hsp70 chaperone machinery subjects misfolded and endoplasmic reticulum import-incompetent proteins to degradation via the ubiquitin-proteasome system

7 April 2017

1 reference

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Sequential quality-control checkpoints triage misfolded cystic fibrosis transmembrane conductance regulator

7 April 2017

1 reference

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BAG-2 acts as an inhibitor of the chaperone-associated ubiquitin ligase CHIP.

7 April 2017

1 reference

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The chaperones MPP11 and Hsp70L1 form the mammalian ribosome-associated complex

7 April 2017

1 reference

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Protein disulphide-isomerase reduces ricin to its A and B chains in the endoplasmic reticulum

7 April 2017

1 reference

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The crystal structure of saporin SO6 from Saponaria officinalis and its interaction with the ribosome

7 April 2017

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Structural basis for inhibition of the Hsp90 molecular chaperone by the antitumor antibiotics radicicol and geldanamycin

7 April 2017

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Dissecting the ER-associated degradation of a misfolded polytopic membrane protein

7 April 2017

1 reference

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Regulation of the cytoplasmic quality control protein degradation pathway by BAG2

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2580750

ERAD: the long road to destruction

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2580750

CHIP is a U-box-dependent E3 ubiquitin ligase: identification of Hsc70 as a target for ubiquitylation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2580750

The ubiquitin-related BAG-1 provides a link between the molecular chaperones Hsc70/Hsp70 and the proteasome

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2580750

Hop as an adaptor in the heat shock protein 70 (Hsp70) and hsp90 chaperone machinery

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2580750

Hip, a novel cochaperone involved in the eukaryotic hsc70/hsp40 reaction cycle

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2580750

The Hsc70 co-chaperone CHIP targets immature CFTR for proteasomal degradation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2580750

The recognition and retrotranslocation of misfolded proteins from the endoplasmic reticulum

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2580750

To be, or not to be--molecular chaperones in protein degradation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2580750

The protective and destructive roles played by molecular chaperones during ERAD (endoplasmic-reticulum-associated degradation).

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2580750

The in vivo function of the ribosome-associated Hsp70, Ssz1, does not require its putative peptide-binding domain

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2580750

The low lysine content of ricin A chain reduces the risk of proteolytic degradation after translocation from the endoplasmic reticulum to the cytosol

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2580750

Retrograde transport of mutant ricin to the endoplasmic reticulum with subsequent translocation to cytosol

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2580750

Accumulating Evidence Suggests That Several AB-Toxins Subvert the Endoplasmic Reticulum-Associated Protein Degradation Pathway To Enter Target Cells

27 September 2017

1 reference

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Temporal separation of protein toxin translocation from processing events

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2580750

Estimation of the amount of internalized ricin that reaches the trans-Golgi network

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2580750

Ribosome-mediated folding of partially unfolded ricin A-chain.

30 May 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0809013105

Mutagenesis and kinetic analysis of the active site Glu177 of ricin A-chain.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0809013105

CHIP promotes proteasomal degradation of familial ALS-linked mutant SOD1 by ubiquitinating Hsp/Hsc70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0809013105

Apoprotein B degradation is promoted by the molecular chaperones hsp90 and hsp70.

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0809013105

Binding of ricin A-chain to negatively charged phospholipid vesicles leads to protein structural changes and destabilizes the lipid bilayer

21 January 2018

1 reference

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Geldanamycin, an hsp90/GRP94-binding drug, induces increased transcription of endoplasmic reticulum (ER) chaperones via the ER stress pathway

28 November 2018

1 reference

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Addition of an endoplasmic reticulum retrieval sequence to ricin A chain significantly increases its cytotoxicity to mammalian cells.

28 November 2018

1 reference

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Dependence of ricin toxicity on translocation of the toxin A-chain from the endoplasmic reticulum to the cytosol

28 November 2018

1 reference

12 December 2020

Quantitation of the interaction of the immunosuppressant deoxyspergualin and analogs with Hsc70 and Hsp90

1 reference

12 December 2020

Introduction of a disulfide bond into ricin A chain decreases the cytotoxicity of the ricin holotoxin

1 reference

12 December 2020

Ligand interactions in the adenosine nucleotide-binding domain of the Hsp90 chaperone, GRP94. I. Evidence for allosteric regulation of ligand binding

1 reference

12 December 2020

Energetics of diphtheria toxin membrane insertion and translocation: calorimetric characterization of the acid pH induced transition

1 reference

12 December 2020

Selectivity of the molecular chaperone-specific immunosuppressive agent 15-deoxyspergualin: modulation of Hsc70 ATPase activity without compromising DnaJ chaperone interactions

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0809013105

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:18988734 AND SRC:MED&resulttype=core&format=json

25 December 2019

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24 November 2022

mapped directly with Wikidata item

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25 December 2019

PubMed publication ID

18988734

1 reference