MEKK2 gene disruption causes loss of cytokine production in response to IgE and c-Kit ligand stimulation of ES cell-derived mast cells (Q24631045)

2

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P J Papst

3

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K Chayama

4

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S Webb

5

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T Yujiri

6

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W Sun

7

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S Sather

8

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D M Russell

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S B Gibson

10

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G Keller

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E W Gelfand

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G L Johnson

MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42

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language of work or name

English

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publication date

16 October 2000

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published in

The EMBO Journal

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volume

19

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issue

20

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page(s)

5387-95

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cites work

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Recombinant NFAT1 (NFATp) is regulated by calcineurin in T cells and mediates transcription of several cytokine genes

7 April 2017

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Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase

7 April 2017

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MEK kinase 2 binds and activates protein kinase C-related kinase 2. Bifurcation of kinase regulatory pathways at the level of an MAPK kinase kinase

7 April 2017

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JNK is required for effector T-cell function but not for T-cell activation

7 April 2017

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Role of MEKK1 in cell survival and activation of JNK and ERK pathways defined by targeted gene disruption

7 April 2017

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Bmk1/Erk5 is required for cell proliferation induced by epidermal growth factor

7 April 2017

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7 April 2017

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A MAP kinase targeted by endotoxin and hyperosmolarity in mammalian cells

7 April 2017

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Big mitogen-activated protein kinase 1 (BMK1) is a redox-sensitive kinase

7 April 2017

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Mitogen-activated protein kinase: conservation of a three-kinase module from yeast to human

7 April 2017

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Identification of an oncoprotein- and UV-responsive protein kinase that binds and potentiates the c-Jun activation domain

7 April 2017

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Live cell fluorescence imaging of T cell MEKK2: redistribution and activation in response to antigen stimulation of the T cell receptor.

7 April 2017

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Transcriptional regulation of the interleukin-6 gene in mesangial cells

27 September 2017

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Organization and regulation of mitogen-activated protein kinase signaling pathways

27 September 2017

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Stem cell factor augments Fc epsilon RI-mediated TNF-alpha production and stimulates MAP kinases via a different pathway in MC/9 mast cells.

27 September 2017

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Comparative cytokine gene expression: regulation and release by human mast cells

27 September 2017

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Impaired CD28-mediated interleukin 2 production and proliferation in stress kinase SAPK/ERK1 kinase (SEK1)/mitogen-activated protein kinase kinase 4 (MKK4)-deficient T lymphocytes.

27 September 2017

1 reference

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Mast cell tumor necrosis factor alpha production is regulated by MEK kinases

27 September 2017

1 reference

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Lymphokine and cytokine production by Fc epsilon RI cells

27 September 2017

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Coordinate and cooperative roles for NF-AT and AP-1 in the regulation of the murine IL-4 gene

27 September 2017

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Ultrastructural criteria for identification of mast cells and basophils in humans, guinea pigs, and mice

27 September 2017

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Activating transcription factor-2 DNA-binding activity is stimulated by phosphorylation catalyzed by p42 and p54 microtubule-associated protein kinases

27 September 2017

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Cell surface structures on human basophils and mast cells: biochemical and functional characterization

27 September 2017

1 reference

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Human lung mast cell activation leads to IL-13 mRNA expression and protein release

27 September 2017

1 reference

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Multiple transcription factors are required for activation of human interleukin 9 gene in T cells

27 September 2017

1 reference

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Aggregation of the FcepsilonRI on mast cells stimulates c-Jun amino-terminal kinase activity. A response inhibited by wortmannin

27 September 2017

1 reference

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Genes that regulate interleukin-4 expression in T cells

27 September 2017

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The Role of Nuclear Factor- κ B in Cytokine Gene Regulation

30 May 2018

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Signals for activation of the GM-CSF promoter and enhancer in T cells

30 May 2018

1 reference

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Regulation of interleukin-2 transcription by inducible stable expression of dominant negative and dominant active mitogen-activated protein kinase kinase kinase in jurkat T cells. Evidence for the importance of Ras in a pathway that is controlled by

30 May 2018

1 reference

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Berberine sulphate binding to mast cell polyanions: a cytofluorometric method for the quantitation of heparin.

30 May 2018

1 reference

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MEK kinase 1 (MEKK1) transduces c-Jun NH2-terminal kinase activation in response to changes in the microtubule cytoskeleton

30 May 2018

1 reference

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Mitogen-activated protein kinase activation through Fc epsilon receptor I and stem cell factor receptor is differentially regulated by phosphatidylinositol 3-kinase and calcineurin in mouse bone marrow-derived mast cells

28 November 2018

1 reference

12 December 2020

Mast cell lines produce lymphokines in response to cross-linkage of FcεRI or to calcium ionophores

1 reference

12 December 2020

Activation of MAP kinases, pp90rsk and pp70-S6 kinases in mouse mast cells by signaling through the c-kit receptor tyrosine kinase or Fc epsilon RI: rapamycin inhibits activation of pp70-S6 kinase and proliferation in mouse mast cells

1 reference

12 December 2020

Multiple cytokine mRNA expression in human mast cells stimulated via Fc epsilon RI

1 reference

12 December 2020

IgE-dependent expression of mRNA for IL-4 and IL-5 in human lung mast cells

1 reference

12 December 2020

Human lung mast cell IL-5 gene and protein expression: temporal analysis of upregulation following IgE-mediated activation

1 reference

12 December 2020

Differential release of mast cell interleukin-6 via c-kit

1 reference

12 December 2020