Mouse and human eosinophils degranulate in response to platelet-activating factor (PAF) and lysoPAF via a PAF-receptor-independent mechanism: evidence for a novel receptor (Q24629279)

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English	Mouse and human eosinophils degranulate in response to platelet-activating factor (PAF) and lysoPAF via a PAF-receptor-independent mechanism: evidence for a novel receptor	scientific article

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1 February 2020

Mouse and human eosinophils degranulate in response to platelet-activating factor (PAF) and lysoPAF via a PAF-receptor-independent mechanism: evidence for a novel receptor (English)

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1 February 2020

human eosinophil

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1 February 2020

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Kimberly D Dyer

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1 February 2020

Caroline M Percopo

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1 February 2020

Zhihui Xie

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Zhao Yang

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John Dongil Kim

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Francis Davoine

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Kirk M Druey

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Redwan Moqbel

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Helene F Rosenberg

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Journal of Immunology

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6327-6334

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1 February 2020

Expression of human platelet-activating factor receptor gene in EoL-1 cells following butyrate-induced differentiation

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7 April 2017

Leukocyte-dependent histamine release from rabbit platelets. The role of IgE, basophils, and a platelet-activating factor

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7 April 2017

Previously postulated "ligand-independent" signaling of GPR4 is mediated through proton-sensing mechanisms

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7 April 2017

Lysophospholipid receptors: signalling, pharmacology and regulation by lysophospholipid metabolism

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7 April 2017

Lysophosphatidylcholine impairs endothelial barrier function through the G protein-coupled receptor GPR4

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7 April 2017

The G Protein-Coupled Receptor GPR4 Suppresses ERK Activation in a Ligand-Independent Manner

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7 April 2017

Platelet-activating factor receptor

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7 April 2017

A single enzyme catalyzes both platelet-activating factor production and membrane biogenesis of inflammatory cells. Cloning and characterization of acetyl-CoA:LYSO-PAF acetyltransferase

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7 April 2017

Platelet-activating factor (PAF) receptor and genetically engineered PAF receptor mutant mice

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7 April 2017

Isolation of human eosinophils: microbead method has no impact on IL-5 sustained viability

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27 September 2017

Agonists of the orphan human G2A receptor identified from inducible G2A expression and beta-lactamase reporter screen

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27 September 2017

Newly discovered roles for basophils: a neglected minority gains new respect.

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27 September 2017

Human eosinophils constitutively express multiple Th1, Th2, and immunoregulatory cytokines that are secreted rapidly and differentially

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27 September 2017

Lipid mediators in health and disease: enzymes and receptors as therapeutic targets for the regulation of immunity and inflammation

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27 September 2017

Functionally competent eosinophils differentiated ex vivo in high purity from normal mouse bone marrow

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27 September 2017

PDGF-induced human airway smooth muscle cell proliferation requires STAT3 and the small GTPase Rac1.

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27 September 2017

Platelet activating factor as a mediator and therapeutic approach in bronchial asthma

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27 September 2017

Platelet-activating factor, PAF acetylhydrolase, and severe anaphylaxis

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27 September 2017

Mechanisms of eosinophil secretion: large vesiculotubular carriers mediate transport and release of granule-derived cytokines and other proteins

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27 September 2017

Anaphylaxis: lessons from mouse models

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27 September 2017

Eosinophil trafficking in allergy and asthma.

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27 September 2017

Plasma PAF-acetylhydrolase: an unfulfilled promise?

1 reference

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27 September 2017

Cytokine receptor-mediated trafficking of preformed IL-4 in eosinophils identifies an innate immune mechanism of cytokine secretion.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

27 September 2017

beta-Arrestin 1 participates in platelet-activating factor receptor-mediated endocytosis of Streptococcus pneumoniae

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

27 September 2017

Human eosinophils secrete preformed, granule-stored interleukin-4 through distinct vesicular compartments.

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27 September 2017

Intragranular vesiculotubular compartments are involved in piecemeal degranulation by activated human eosinophils.

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27 September 2017

Eosinophil degranulation: an evolutionary vestige or a universally destructive effector function?

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27 September 2017

Molecular mechanisms of anaphylaxis: lessons from studies with murine models.

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27 September 2017

Chemokine receptor antagonists: a novel therapeutic approach in allergic diseases

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27 September 2017

Dual signaling and effector pathways mediate human eosinophil activation by platelet-activating factor

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

27 September 2017

Cytokines and chemoattractants in allergic inflammation

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

27 September 2017

Role of platelet-activating factor in cardiovascular pathophysiology.

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

27 September 2017

Eosinophil cytokines

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

27 September 2017

Impaired anaphylactic responses with intact sensitivity to endotoxin in mice lacking a platelet-activating factor receptor

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27 September 2017

Platelet-activating factor antagonists: scientific background and possible clinical applications.

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27 September 2017

Platelet-activating factor: the biosynthetic and catabolic enzymes

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27 September 2017

Platelet activating factor antagonists

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27 September 2017

Platelet-activating factor. A potent chemotactic and chemokinetic factor for human eosinophils.

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27 September 2017

Platelet activating factor: a biologically active phosphoglyceride

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27 September 2017

Eosinophilia in transgenic mice expressing interleukin 5.

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27 September 2017

Opposing effects of platelet-activating factor and lyso-platelet-activating factor on neutrophil and platelet activation

1 reference

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30 May 2018

Inhibition of protein kinases A and C demonstrates dual modes of response in human eosinophils stimulated with platelet-activating factor

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30 May 2018

Bronchoconstriction Induced by Platelet-Activating Factor in the Guinea Pig and Its Inhibition by CV-3988, a PAF Antagonist: Serial Changes in Findings of Lung Histology and Bronchoalveolar Lavage Cell Population

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

30 May 2018

Stimulation of degranulation from human eosinophils by platelet-activating factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

30 May 2018

Cloning by functional expression of platelet-activating factor receptor from guinea-pig lung

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

30 May 2018

The effect of platelet-activating factor on the generation of superoxide anion in human eosinophils and neutrophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

30 May 2018

Vesicle-mediated secretion of human eosinophil granule-derived major basic protein.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

28 November 2018

Eosinophils: biological properties and role in health and disease

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

28 November 2018

Basophils play a pivotal role in immunoglobulin-G-mediated but not immunoglobulin-E-mediated systemic anaphylaxis

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

28 November 2018

Fibroblast growth factor 2 and transforming growth factor beta1 synergism in human bronchial smooth muscle cell proliferation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

28 November 2018

Platelet-activating factor stimulates cytoplasmic alkalinization and granule acidification in human eosinophils

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

28 November 2018

The induction of eosinophil peroxidase release: improved methods of measurement and stimulation

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

28 November 2018

Platelet-activating factor receptor develops airway hyperresponsiveness independently of airway inflammation in a murine asthma model

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

28 November 2018

Eosinophil degranulation in the allergic lung of mice primarily occurs in the airway lumen

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

28 November 2018

Distinct isoforms of protein kinase C are involved in human eosinophil functions induced by platelet-activating factor

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3406327

28 November 2018

PAF-receptors on eosinophils: identification with a novel ligand, [3H]WEB 2086.

1 reference

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28 November 2018

Characterization of platelet-activating factor-induced cytosolic calcium mobilization in human eosinophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Effect of recombinant human platelet-activating factor-acetylhydrolase on allergen-induced asthmatic responses

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Cutting edge: eotaxin elicits rapid vesicular transport-mediated release of preformed IL-4 from human eosinophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Evidence for an association between plasma platelet-activating factor acetylhydrolase deficiency and increased risk of childhood atopic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Role of interleukin-13 in eosinophil accumulation and airway remodelling in a mouse model of chronic asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Stimulation of eosinophil adherence to human vascular endothelial cells in vitro by platelet-activating factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

The effect of WEB 2086 on PAF-induced eosinophil chemotaxis and LTC4 production from eosinophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

CD11b/CD18 (Mac-1) is required for degranulation of human eosinophils induced by human recombinant granulocyte-macrophage colony-stimulating factor and platelet-activating factor

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Specific high affinity binding of platelet activating factor to intact human blood neutrophils and eosinophils

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Detection of IL-5 and IL-1 receptor antagonist in bronchoalveolar lavage fluid in acute eosinophilic pneumonia

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Platelet-activating factor antagonists

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Release of granule proteins from human eosinophils stimulated with mast-cell mediators

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Recombinant human platelet-activating factor-acetylhydrolase inhibits airway inflammation and hyperreactivity in mouse asthma model

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Coexpression of IL-5 and eotaxin-2 in mice creates an eosinophil-dependent model of respiratory inflammation with characteristics of severe asthma

1 reference

https://pubmed.ncbi.nlm.nih.gov/20421642

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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10.4049/JIMMUNOL.0904043

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1 February 2020

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1 February 2020

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1 February 2020

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