Generation of pathogenic T(H)17 cells in the absence of TGF-β signalling (Q24625230)

Xiang-Ping Yang

3

0 references

John R Grainger

John R Grainger

11

0 references

Yuka Kanno

Yuka Kanno

13

0 references

Gérard Eberl

Gérard Eberl

16

0 references

Arian Laurence

Arian Laurence

2

0 references

Yasmine Belkaid

Yasmine Belkaid

18

0 references

Cristina M Tato

4

Cristina M Tato

0 references

Joanne E Konkel

6

Joanne E Konkel

0 references

Kamran Ghoreschi

1

Kamran Ghoreschi

0 references

Mandy J McGeachy

5

Mandy J McGeachy

0 references

Haydeé L Ramos

7

Haydeé L Ramos

0 references

Wendy T Watford

14

Wendy T Watford

0 references

Ethan M. Shevach

17

Ethan M Shevach

0 references

Lai Wei

8

Lai Wei

0 references

author name string

Todd S Davidson

9

0 references

Qian Chen

12

0 references

Hong-Wei Sun

15

0 references

Daniel J Cua

19

0 references

Wanjun Chen

20

0 references

John J O'Shea

The interleukin 23 receptor is essential for the terminal differentiation of interleukin 17-producing effector T helper cells in vivo

21

0 references

language of work or name

English

0 references

publication date

21 October 2010

0 references

published in

Nature

0 references

volume

467

0 references

issue

7318

0 references

page(s)

967-71

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

The orphan nuclear receptor RORgammat directs the differentiation program of proinflammatory IL-17 T helper cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

Reciprocal developmental pathways for the generation of pathogenic effector TH17 and regulatory T cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

Interleukin-17 and type 17 helper T cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

Transforming growth factor-beta induces development of the T(H)17 lineage

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

TGFbeta in the context of an inflammatory cytokine milieu supports de novo differentiation of IL-17-producing T cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

Interleukin-23 promotes a distinct CD4 T cell activation state characterized by the production of interleukin-17

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

Interleukin 17-producing CD4 effector T cells develop via a lineage distinct from the T helper type 1 and 2 lineages

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

A distinct lineage of CD4 T cells regulates tissue inflammation by producing interleukin 17

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

Interleukins 1beta and 6 but not transforming growth factor-beta are essential for the differentiation of interleukin 17-producing human T helper cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

Development, cytokine profile and function of human interleukin 17-producing helper T cells

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

IL-17 family cytokines and the expanding diversity of effector T cell lineages

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

Interleukin-23 rather than interleukin-12 is the critical cytokine for autoimmune inflammation of the brain

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

Transforming growth factor beta is dispensable for the molecular orchestration of Th17 cell differentiation

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

IL-9 as a mediator of Th17-driven inflammatory disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

T-bet is essential for encephalitogenicity of both Th1 and Th17 cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

Plasticity of CD4 T cell lineage differentiation.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

IL-9 induces differentiation of TH17 cells and enhances function of FoxP3 natural regulatory T cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

Late developmental plasticity in the T helper 17 lineage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

In vivo equilibrium of proinflammatory IL-17 and regulatory IL-10 Foxp3 RORgamma t T cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

TGF-beta and IL-6 drive the production of IL-17 and IL-10 by T cells and restrain T(H)-17 cell-mediated pathology

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

Distinct regulation of interleukin-17 in human T helper lymphocytes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

Differentiation and function of Th17 T cells

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

Loss of T-bet, but not STAT1, prevents the development of experimental autoimmune encephalomyelitis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

The transcription factor T-bet controls regulatory T cell homeostasis and function during type 1 inflammation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

T-bet is required for optimal proinflammatory CD4 T-cell trafficking.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

Preferential recruitment of interferon-gamma-expressing TH17 cells in multiple sclerosis.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

Signals mediated by transforming growth factor-beta initiate autoimmune encephalomyelitis, but chronic inflammation is needed to sustain disease.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3108066

Interleukin 18-independent engagement of interleukin 18 receptor-alpha is required for autoimmune inflammation

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20962846

12 December 2020

inferred from PubMed ID database lookup

A critical function for TGF-beta signaling in the development of natural CD4 CD25 Foxp3 regulatory T cells

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20962846

12 December 2020

inferred from PubMed ID database lookup

Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4 T cells

1 reference

7 January 2021

Diverse targets of the transcription factor STAT3 contribute to T cell pathogenicity and homeostasis.

1 reference

7 January 2021

Interleukin-2 signaling via STAT5 constrains T helper 17 cell generation

1 reference

7 January 2021

IL-21 is produced by Th17 cells and drives IL-17 production in a STAT3-dependent manner

1 reference

7 January 2021

Identifiers

DOI

10.1038/NATURE09447

1 reference

Dimensions Publication ID

1025981728

0 references

1 reference

1 reference

PubMed publication ID

20962846

1 reference