Central role of the P2Y12 receptor in platelet activation (Q24618777)

Journal of Clinical Investigation

Europe PubMed Central

title

Central role of the P2Y12 receptor in platelet activation (English)

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author name string

Robert T Dorsam

series ordinal

1

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Satya P Kunapuli

series ordinal

2

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language of work or name

English

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publication date

February 2004

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published in

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volume

113

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issue

3

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page(s)

340-5

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cites work

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Blockade of the platelet P2Y12 receptor by AR-C69931MX sustains coronary artery recanalization and improves the myocardial tissue perfusion in a canine thrombosis model

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28 November 2018

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Costimulation of Gi- and G12/G13-mediated signaling pathways induces integrin alpha IIbbeta 3 activation in platelets

28 November 2018

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Functional significance of adenosine 5'-diphosphate receptor (P2Y(12)) in platelet activation initiated by binding of von Willebrand factor to platelet GP Ibalpha induced by conditions of high shear rate

28 November 2018

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28 November 2018

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Adenosine diphosphate (ADP)-induced thromboxane A(2) generation in human platelets requires coordinated signaling through integrin alpha(IIb)beta(3) and ADP receptors

28 November 2018

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28 November 2018

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28 November 2018

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Platelets from a patient heterozygous for the defect of P2CYC receptors for ADP have a secretion defect despite normal thromboxane A2 production and normal granule stores: further evidence that some cases of platelet 'primary secretion defect' are h

28 November 2018

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ADP receptors of platelets and their inhibition

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12 December 2020

Deficiency of (33P)2MeS-ADP binding sites on platelets with secretion defect, normal granule stores and normal thromboxane A2 production. Evidence that ADP potentiates platelet secretion independently of the formation of large platelet aggregates an

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Signaling through G proteins in platelets: to the integrins and beyond

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12 December 2020

ADP induces partial platelet aggregation without shape change and potentiates collagen-induced aggregation in the absence of Galphaq

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Potentiation of thromboxane A2-induced platelet secretion by Gi signaling through the phosphoinositide-3 kinase pathway

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IL-4 synergistically enhances both IL-2- and IL-12-induced IFN-gamma expression in murine NK cells

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