An ER-mitochondria tethering complex revealed by a synthetic biology screen (Q24618405)

Gene Ontology release 2020-05-02

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:0032865

mitochondrion-endoplasmic reticulum membrane tethering

1 reference

Gene Ontology release 2020-05-02

Gene Ontology ID

GO:1990456

ERMES complex subunit MDM34 YGL219C

1 reference

Mdm10p YAL010C

1 reference

ERMES complex subunit MMM1 YLL006W

1 reference

ERMES complex subunit MDM12 YOL009C

1 reference

1 reference

1 reference

4

Maya Schuldiner

Maya

Schuldiner

1 reference

19 January 2024

1

Benoît Kornmann

Benoît

Kornmann

1 reference

19 January 2024

Sean R Collins

3

Sean R

Collins

1 reference

19 January 2024

6

Jonathan S Weissman

Jonathan S

Weissman

1 reference

19 January 2024

7

Peter Walter

Peter

Walter

1 reference

19 January 2024

5

Jodi Nunnari

Jodi

Nunnari

1 reference

19 January 2024

Erin Currie

2

Erin

Currie

1 reference

19556461

The mechanism of Ca2 -dependent regulation of kinesin-mediated mitochondrial motility

19 January 2024

language of work or name

English

0 references

publication date

24 July 2009

0 references

published in

Science

0 references

volume

325

0 references

issue

5939

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page(s)

477-81

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Diverse membrane-associated proteins contain a novel SMP domain

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Global analysis of protein expression in yeast

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

The genetic interactome of prohibitins: coordinated control of cardiolipin and phosphatidylethanolamine by conserved regulators in mitochondria

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

The morphology proteins Mdm12/Mmm1 function in the major beta-barrel assembly pathway of mitochondria

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Exploration of the function and organization of the yeast early secretory pathway through an epistatic miniarray profile

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Yeast Miro GTPase, Gem1p, regulates mitochondrial morphology via a novel pathway.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Mmm2p, a mitochondrial outer membrane protein required for yeast mitochondrial shape and maintenance of mtDNA nucleoids.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

A protein complex containing Mdm10p, Mdm12p, and Mmm1p links mitochondrial membranes and DNA to the cytoskeleton-based segregation machinery

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Isolation and characterization of the gene (CLS1) encoding cardiolipin synthase in Saccharomyces cerevisiae

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Mdm12p, a component required for mitochondrial inheritance that is conserved between budding and fission yeast

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Temperature-sensitive yeast mutants defective in mitochondrial inheritance

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Sigma-1 receptor chaperones at the ER-mitochondrion interface regulate Ca(2 ) signaling and cell survival

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Newly made phosphatidylserine and phosphatidylethanolamine are preferentially translocated between rat liver mitochondria and endoplasmic reticulum

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Mitofusin 2 tethers endoplasmic reticulum to mitochondria

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Close contacts with the endoplasmic reticulum as determinants of mitochondrial Ca2 responses

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Cloning genes by complementation in yeast

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Calcium and apoptosis: ER-mitochondria Ca2 transfer in the control of apoptosis

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Chaperone-mediated coupling of endoplasmic reticulum and mitochondrial Ca2 channels.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Structural and functional features and significance of the physical linkage between ER and mitochondria.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Synthetic lethal interaction of the mitochondrial phosphatidylethanolamine and cardiolipin biosynthetic pathways in Saccharomyces cerevisiae

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

PACS-2 controls endoplasmic reticulum-mitochondria communication and Bid-mediated apoptosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Evidence for a two membrane–spanning autonomous mitochondrial DNA replisome

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

New perspectives on the regulation of intermembrane glycerophospholipid traffic

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Roles of phosphatidylethanolamine and of its several biosynthetic pathways in Saccharomyces cerevisiae

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Mitotic stability of yeast chromosomes: a colony color assay that measures nondisjunction and chromosome loss

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Rapid changes of mitochondrial Ca2 revealed by specifically targeted recombinant aequorin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Dissecting membrane insertion of mitochondrial beta-barrel proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Mmm1p spans both the outer and inner mitochondrial membranes and contains distinct domains for targeting and foci formation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2933203

Microdomains with high Ca2 close to IP3-sensitive channels that are sensed by neighboring mitochondria

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/19556461

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identification of a non-mitochondrial phosphatidylserine decarboxylase activity (PSD2) in the yeast Saccharomyces cerevisiae

1 reference

https://pubmed.ncbi.nlm.nih.gov/19556461

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Association between the endoplasmic reticulum and mitochondria of yeast facilitates interorganelle transport of phospholipids through membrane contact

1 reference

https://pubmed.ncbi.nlm.nih.gov/19556461

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1175088

1 reference

1 reference

1 reference

19556461

1 reference