Nutrient-sensitive mitochondrial NAD levels dictate cell survival (Q24612868)

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8 January 2020

title

Nutrient-sensitive mitochondrial NAD levels dictate cell survival (English)

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1 reference

3

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Dudley W Lamming

7

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8 January 2020

Nadja C Souza-Pinto

8

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Rafael de Cabo

11

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David A. Sinclair

13

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9

Vilhelm A Bohr

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8 January 2020

author name string

Hongying Yang

1

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8 January 2020

Tianle Yang

2

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8 January 2020

Evelyn Perez

4

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8 January 2020

Takashi Matsui

5

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Juan J Carmona

6

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Anthony Rosenzweig

10

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Anthony A Sauve

12

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8 January 2020

language of work or name

English

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publication date

1 September 2007

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8 January 2020

volume

130

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issue

6

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8 January 2020

page(s)

1095-1107

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SIRT4 inhibits glutamate dehydrogenase and opposes the effects of calorie restriction in pancreatic beta cells

8 January 2020

cites work

1 reference

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Sirtuins deacetylate and activate mammalian acetyl-CoA synthetases

7 April 2017

1 reference

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Subcellular compartmentation and differential catalytic properties of the three human nicotinamide mononucleotide adenylyltransferase isoforms

7 April 2017

1 reference

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Sir2 mediates longevity in the fly through a pathway related to calorie restriction

7 April 2017

1 reference

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On the origin of mitochondria: a genomics perspective

7 April 2017

1 reference

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The human silent information regulator (Sir)2 homologue hSIRT3 is a mitochondrial nicotinamide adenine dinucleotide-dependent deacetylase

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

The SIR2/3/4 complex and SIR2 alone promote longevity in Saccharomyces cerevisiae by two different mechanisms

7 April 2017

1 reference

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Cloning and characterization of the cDNA encoding a novel human pre-B-cell colony-enhancing factor

7 April 2017

1 reference

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Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

7 April 2017

1 reference

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Identification of the mitochondrial NAD transporter in Saccharomyces cerevisiae

7 April 2017

1 reference

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Discoveries of nicotinamide riboside as a nutrient and conserved NRK genes establish a Preiss-Handler independent route to NAD in fungi and humans

7 April 2017

1 reference

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Longevity regulation in Saccharomyces cerevisiae: linking metabolism, genome stability, and heterochromatin

7 April 2017

1 reference

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Nicotinamide and PNC1 govern lifespan extension by calorie restriction in Saccharomyces cerevisiae

7 April 2017

1 reference

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Manipulation of a nuclear NAD salvage pathway delays aging without altering steady-state NAD levels

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

A phylogenetically conserved NAD -dependent protein deacetylase activity in the Sir2 protein family.

7 April 2017

1 reference

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The membrane of peroxisomes in Saccharomyces cerevisiae is impermeable to NAD(H) and acetyl-CoA under in vivo conditions

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Increased dosage of a sir-2 gene extends lifespan in Caenorhabditis elegans

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Phylogenetic classification of prokaryotic and eukaryotic Sir2-like proteins

7 April 2017

1 reference

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7 April 2017

Mitochondrial evolution

1 reference

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Poly(ADP-ribose) polymerase-1-dependent cardiac myocyte cell death during heart failure is mediated by NAD depletion and reduced Sir2alpha deacetylase activity

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

The NAD biosynthesis pathway mediated by nicotinamide phosphoribosyltransferase regulates Sir2 activity in mammalian cells

7 April 2017

1 reference

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Growth phase-dependent changes in the subcellular localization of pre-B-cell colony-enhancing factor

7 April 2017

1 reference

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Sirtuin activators mimic caloric restriction and delay ageing in metazoans

7 April 2017

1 reference

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Suppression of reactive oxygen species and neurodegeneration by the PGC-1 transcriptional coactivators

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Metabolic control through the PGC-1 family of transcription coactivators

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Increased nuclear NAD biosynthesis and SIRT1 activation prevent axonal degeneration

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Mediation of poly(ADP-ribose) polymerase-1-dependent cell death by apoptosis-inducing factor

7 April 2017

1 reference

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An enzymatic activity in the yeast Sir2 protein that is essential for gene silencing

7 April 2017

1 reference

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The p66shc adaptor protein controls oxidative stress response and life span in mammals

7 April 2017

1 reference

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Sirtuins: a conserved key unlocking AceCS activity

7 April 2017

1 reference

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Nampt/PBEF/Visfatin: a regulator of mammalian health and longevity?

27 September 2017

1 reference

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The simultaneous measurement of nicotinamide adenine dinucleotide and related compounds by liquid chromatography/electrospray ionization tandem mass spectrometry

27 September 2017

1 reference

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Mitochondria and ischemia-reperfusion injury of the heart: fixing a hole

27 September 2017

1 reference

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Inhibition of SIRT1 catalytic activity increases p53 acetylation but does not alter cell survival following DNA damage

27 September 2017

1 reference

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Poly(ADP-ribose). The most elaborate metabolite of NAD .

27 September 2017

1 reference

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The Sir 2 family of protein deacetylases

27 September 2017

1 reference

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Calorie restriction and SIR2 genes--towards a mechanism

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Poly(ADP-ribose) polymerase-1 mediated caspase-independent cell death after ischemia/reperfusion

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Calorie restriction--the SIR2 connection

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Chemical activation of Sir2-dependent silencing by relief of nicotinamide inhibition

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

The emerging therapeutic potential of sirtuin-interacting drugs: from cell death to lifespan extension

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

RETRACTED: Visfatin: a protein secreted by visceral fat that mimics the effects of insulin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Nicotinamide clearance by Pnc1 directly regulates Sir2-mediated silencing and longevity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Pre-B-cell colony-enhancing factor, whose expression is up-regulated in activated lymphocytes, is a nicotinamide phosphoribosyltransferase, a cytosolic enzyme involved in NAD biosynthesis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Cellular senescence and apoptosis: how cellular responses might influence aging phenotypes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Apoptosis in the aging process

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Upregulation of apoptosis with dietary restriction: implications for carcinogenesis and aging

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Regulation of NAD metabolism in Salmonella typhimurium: molecular sequence analysis of the bifunctional nadR regulator and the nadA-pnuC operon

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Macromolecular enzymatic product of NAD in liver mitochondria

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Is contact allergy rare in psoriatics?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Evaluation of a procedure for the simultaneous determination of oxidized and reduced pyridine nucleotides and adenylates in organic phenol extracts from mitochondria

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

A role for SIR-2.1 regulation of ER stress response genes in determining C. elegans life span

30 May 2018

1 reference

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Evolution of NAD Biosynthetic Enzymes

28 November 2018

1 reference

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Involvement of poly(ADP-ribose) polymerase activity in regulating Chk1-dependent apoptotic cell death.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Nuclear poly(ADP-ribose) polymerase-1 rapidly triggers mitochondrial dysfunction

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Antiangiogenic potency of FK866/K22.175, a new inhibitor of intracellular NAD biosynthesis, in murine renal cell carcinoma.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Sir2 regulation by nicotinamide results from switching between base exchange and deacetylation chemistry

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Intra-mitochondrial poly(ADP-ribosylation) contributes to NAD depletion and cell death induced by oxidative stress

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3366687

Impact of aging and life-long calorie restriction on expression of apoptosis-related genes in male F344 rat liver

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17889652

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Adenoviral gene transfer of activated phosphatidylinositol 3'-kinase and Akt inhibits apoptosis of hypoxic cardiomyocytes in vitro

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17889652

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Effect of NAD on Malate Oxidation in Intact Plant Mitochondria

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/17889652

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1016/J.CELL.2007.07.035

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17889652 AND SRC:MED&resulttype=core&format=json

8 January 2020

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:17889652 AND SRC:MED&resulttype=core&format=json

8 January 2020

PubMed publication ID

17889652

2 references