Discovery of a selective NaV1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models (Q24605644)

24 June 2017

title

Discovery of a selective NaV1.7 inhibitor from centipede venom with analgesic efficacy exceeding morphine in rodent pain models (English)

1 reference

24 June 2017

0 references

1 reference

9

Ren Lai

Ren

Lai

1 reference

24 June 2017

8

Mingqiang Rong

Mingqiang

Rong

1 reference

24 June 2017

10

Glenn F King

Glenn F

King

1 reference

24 June 2017

6

Eivind A B Undheim

Eivind A B

Undheim

1 reference

24 June 2017

Shilong Yang

1

Shilong

Yang

1 reference

24 June 2017

Yao Xiao

2

Yao

Xiao

1 reference

24 June 2017

Di Kang

3

Di

Kang

1 reference

24 June 2017

Jie Liu

4

Jie

Liu

1 reference

24 June 2017

Yuan Li

5

Yuan

Li

1 reference

24 June 2017

Julie K Klint

7

Julie K

Klint

1 reference

24 June 2017

language of work or name

English

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publication date

30 September 2013

1 reference

Proceedings of the National Academy of Sciences of the United States of America

24 June 2017

published in

1 reference

24 June 2017

volume

110

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24 June 2017

issue

43

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24 June 2017

page(s)

17534-17539

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Chemical punch packed in venoms makes centipedes excellent predators

24 June 2017

cites work

1 reference

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Distinct Nav1.7-dependent pain sensations require different sets of sensory and sympathetic neurons

7 April 2017

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TRPA1 mediates formalin-induced pain

7 April 2017

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Mutations in SCN9A, encoding a sodium channel alpha subunit, in patients with primary erythermalgia

7 April 2017

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Overview of the voltage-gated sodium channel family

7 April 2017

1 reference

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Sodium channel Na(v)1.6 is localized at nodes of ranvier, dendrites, and synapses

7 April 2017

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A dynamic pharmacophore drives the interaction between Psalmotoxin-1 and the putative drug target acid-sensing ion channel 1a

7 April 2017

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The crystal structure of a voltage-gated sodium channel

7 April 2017

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An SCN9A channelopathy causes congenital inability to experience pain

7 April 2017

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Cellular and Molecular Mechanisms of Pain

7 April 2017

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The Na(V)1.7 sodium channel: from molecule to man.

7 April 2017

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Spider-venom peptides: structure, pharmacology, and potential for control of insect pests.

27 September 2017

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Sea-anemone toxin ATX-II elicits A-fiber-dependent pain and enhances resurgent and persistent sodium currents in large sensory neurons

27 September 2017

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Spider-venom peptides that target voltage-gated sodium channels: pharmacological tools and potential therapeutic leads.

27 September 2017

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Venoms as a platform for human drugs: translating toxins into therapeutics

27 September 2017

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μ-Conotoxins that differentially block sodium channels NaV1.1 through 1.8 identify those responsible for action potentials in sciatic nerve

27 September 2017

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Loss-of-function mutations in sodium channel Nav1.7 cause anosmia.

27 September 2017

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On the venom system of centipedes (Chilopoda), a neglected group of venomous animals

27 September 2017

1 reference

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NMR methods for determining disulfide-bond connectivities

27 September 2017

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Pain perception is altered by a nucleotide polymorphism in SCN9A

27 September 2017

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Targeting voltage-gated sodium channels for pain therapy

27 September 2017

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Subtype-selective targeting of voltage-gated sodium channels

27 September 2017

1 reference

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Deconstructing voltage sensor function and pharmacology in sodium channels

27 September 2017

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Peptide toxins that selectively target insect Na(V) and Ca(V) channels

27 September 2017

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ProTx-II, a selective inhibitor of NaV1.7 sodium channels, blocks action potential propagation in nociceptors.

27 September 2017

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A stop codon mutation in SCN9A causes lack of pain sensation

27 September 2017

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Pain management: a fundamental human right

27 September 2017

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Four novel tarantula toxins as selective modulators of voltage-gated sodium channel subtypes

27 September 2017

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Jingzhaotoxin-III, a novel spider toxin inhibiting activation of voltage-gated sodium channel in rat cardiac myocytes

27 September 2017

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Expression of Nav1.7 in DRG neurons extends from peripheral terminals in the skin to central preterminal branches and terminals in the dorsal horn

27 September 2017

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Loss-of-function mutations in the Nav1.7 gene underlie congenital indifference to pain in multiple human populations

30 May 2018

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The economic costs of pain in the United States

30 May 2018

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Tetraspanin proteins promote multiple cancer stages

21 January 2018

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Localization of Nav 1.7 in the normal and injured rodent olfactory system indicates a critical role in olfaction, pheromone sensing and immune function

21 January 2018

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Expression and characterization of jingzhaotoxin-34, a novel neurotoxin from the venom of the tarantula Chilobrachys jingzhao

21 January 2018

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Sites and molecular mechanisms of modulation of Na(v)1.2 channels by Fyn tyrosine kinase.

21 January 2018

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Molecular basis of the tarantula toxin jingzhaotoxin‐III (β‐TRTX‐Cj1α) interacting with voltage sensors in sodium channel subtype Nav1.5

21 January 2018

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The MinD membrane targeting sequence is a transplantable lipid-binding helix

21 January 2018

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Analgesic and anti-inflammatory effects of the amphibian neurotoxin, anntoxin

21 January 2018

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PubMed

https://pubmed.ncbi.nlm.nih.gov/24082113

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Anti-inflammatory effects and acute toxicity of hydroethanolic extract of Jacaranda decurrens roots in adult male rats

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/24082113

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1073/PNAS.1306285110

1 reference

OpenCitations bibliographic resource ID

24 June 2017

0 references

2657950

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2657950

1 reference