Noggin-mediated antagonism of BMP signaling is required for growth and patterning of the neural tube and somite (Q24602347)

Bone morphogenetic protein 4

1 reference

Sonic hedgehog

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Noggin

1 reference

author name string

J A McMahon

1

0 references

S Takada

2

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L B Zimmerman

3

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C M Fan

4

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R M Harland

5

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A P McMahon

The Spemann organizer signal noggin binds and inactivates bone morphogenetic protein 4

6

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language of work or name

English

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publication date

15 May 1998

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published in

Genes & Development

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volume

12

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issue

10

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page(s)

1438-52

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cites work

1 reference

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Identification of mammalian noggin and its expression in the adult nervous system

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Noggin, cartilage morphogenesis, and joint formation in the mammalian skeleton

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Overlapping expression domains of bone morphogenetic protein family members potentially account for limited tissue defects in BMP7 deficient embryos

7 April 2017

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Cyclopia and defective axial patterning in mice lacking Sonic hedgehog gene function

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Lateral and axial signals involved in avian somite patterning: a role for BMP4

7 April 2017

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Requirement for LIM homeobox gene Isl1 in motor neuron generation reveals a motor neuron-dependent step in interneuron differentiation

7 April 2017

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The signalling molecule BMP4 mediates apoptosis in the rhombencephalic neural crest

7 April 2017

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Bone morphogenetic protein-4 is required for mesoderm formation and patterning in the mouse

7 April 2017

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Dorsal differentiation of neural plate cells induced by BMP-mediated signals from epidermal ectoderm

7 April 2017

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A role for WNT proteins in induction of dermomyotome

7 April 2017

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Pax6 controls progenitor cell identity and neuronal fate in response to graded Shh signaling

7 April 2017

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Disruption of the proto-oncogene int-2 in mouse embryo-derived stem cells: a general strategy for targeting mutations to non-selectable genes

7 April 2017

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Targeted disruption of the c-src proto-oncogene leads to osteopetrosis in mice

7 April 2017

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Regulation of dorsal somitic cell fates: BMPs and Noggin control the timing and pattern of myogenic regulator expression

7 April 2017

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The world according to hedgehog

27 September 2017

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Two critical periods of Sonic Hedgehog signaling required for the specification of motor neuron identity

27 September 2017

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Dorsoventral patterning in Xenopus: inhibition of ventral signals by direct binding of chordin to BMP-4.

27 September 2017

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The formation of somite compartments in the avian embryo

27 September 2017

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Induction of a specific muscle cell type by a hedgehog-like protein in zebrafish.

27 September 2017

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A common plan for dorsoventral patterning in Bilateria

27 September 2017

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Longitudinal organization of the anterior neural plate and neural tube.

27 September 2017

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HNF-3 beta as a regulator of floor plate development

27 September 2017

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Perinatal lethality and defects in hindbrain development in mice homozygous for a targeted mutation of the zinc finger gene Krox20.

27 September 2017

1 reference

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Induction of a second neural axis by the mouse node.

27 September 2017

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Structure and sequence of mouse bone morphogenetic protein-2 gene (BMP-2): comparison of the structures and promoter regions of BMP-2 and BMP-4 genes

27 September 2017

1 reference

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Vertebrate embryonic induction: mesodermal and neural patterning

27 September 2017

1 reference

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Osteogenic protein-1 binds to activin type II receptors and induces certain activin-like effects

27 September 2017

1 reference

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Control of somite patterning by signals from the lateral plate

27 September 2017

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The mouse bone morphogenetic protein-4 gene. Analysis of promoter utilization in fetal rat calvarial osteoblasts and regulation by COUP-TFI orphan receptor

27 September 2017

1 reference

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Mechanisms of neurulation: traditional viewpoint and recent advances

27 September 2017

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Involvement of Bone Morphogenetic Protein-4 (BMP-4) and Vgr-1 in morphogenesis and neurogenesis in the mouse

27 September 2017

1 reference

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How is myogenesis initiated in the embryo?

27 September 2017

1 reference

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Diversity and pattern in the developing spinal cord

27 September 2017

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Patterning of mammalian somites by surface ectoderm and notochord: evidence for sclerotome induction by a hedgehog homolog

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316831

Multiple defects and perinatal death in mice deficient in follistatin

27 September 2017

1 reference

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Formation and function of Spemann's organizer

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316831

Coordinate actions of BMPs, Wnts, Shh and noggin mediate patterning of the dorsal somite.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316831

Cooperation of BMP7 and SHH in the induction of forebrain ventral midline cells by prechordal mesoderm.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316831

Frzb-1 is a secreted antagonist of Wnt signaling expressed in the Spemann organizer

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316831

The role of bone morphogenetic proteins in vertebral development.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316831

Neural induction by the secreted polypeptide noggin

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316831

Follistatin, an antagonist of activin, is expressed in the Spemann organizer and displays direct neuralizing activity

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316831

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30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316831

Expression of inhibin subunits and follistatin during postimplantation mouse development: decidual expression of activin and expression of follistatin in primitive streak, somites and hindbrain.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316831

Activin-binding protein from rat ovary is follistatin

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316831

The midbrain-hindbrain phenotype of Wnt-1-/Wnt-1- mice results from stepwise deletion of engrailed-expressing cells by 9.5 days postcoitum

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316831

The neural tube/notochord complex is necessary for vertebral but not limb and body wall striated muscle differentiation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316831

Expression cloning of noggin, a new dorsalizing factor localized to the Spemann organizer in Xenopus embryos

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316831

A role for the roof plate and its resident TGFbeta-related proteins in neuronal patterning in the dorsal spinal cord

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=316831

Frzb, a secreted protein expressed in the Spemann organizer, binds and inhibits Wnt-8.

28 November 2018

1 reference

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28 November 2018

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28 November 2018

1 reference

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Secreted noggin protein mimics the Spemann organizer in dorsalizing Xenopus mesoderm

28 November 2018

1 reference

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Ectopic expression of Sonic hedgehog alters dorsal-ventral patterning of somites.

28 November 2018

1 reference

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1 reference

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1 reference

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1 reference

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Identifiers

DOI

10.1101/GAD.12.10.1438

1 reference

1 reference

1 reference

PubMed publication ID

9585504

1 reference