Holotranscobalamin, a marker of vitamin B-12 status: analytical aspects and clinical utility (Q24600759)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21593496 AND SRC:MED&resulttype=core&format=json

1 February 2020

review article

1 reference

title

Holotranscobalamin, a marker of vitamin B-12 status: analytical aspects and clinical utility (English)

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21593496 AND SRC:MED&resulttype=core&format=json

1 February 2020

main subject

vitamin B12 deficiency

9 references

14 March 2019

19 March 2019

24 March 2019

19 June 2019

17 September 2019

13 November 2019

27 November 2019

28 November 2019

13 December 2019

heterocyclic compound

1 reference

17 September 2019

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13 November 2019

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27 November 2019

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28 November 2019

1 reference

13 December 2019

1

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21593496 AND SRC:MED&resulttype=core&format=json

1 February 2020

author name string

Elke Hoffmann-Lücke

series ordinal

2

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21593496 AND SRC:MED&resulttype=core&format=json

1 February 2020

language of work or name

English

0 references

publication date

18 May 2011

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21593496 AND SRC:MED&resulttype=core&format=json

American Journal of Clinical Nutrition

1 February 2020

published in

10 references

14 March 2019

19 March 2019

24 March 2019

19 June 2019

17 September 2019

13 November 2019

27 November 2019

28 November 2019

13 December 2019

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21593496 AND SRC:MED&resulttype=core&format=json

1 February 2020

volume

94

1 reference

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1 February 2020

issue

1

1 reference

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1 February 2020

page(s)

359S-365S

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21593496 AND SRC:MED&resulttype=core&format=json

Transcobalamin C776G genotype modifies the association between vitamin B12 and homocysteine in older Hispanics

1 February 2020

cites work

1 reference

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The protein and the gene encoding the receptor for the cellular uptake of transcobalamin-bound cobalamin

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Characterization of a monoclonal antibody with specificity for holo-transcobalamin.

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

The cDNA sequence and the deduced amino acid sequence of human transcobalamin II show homology with rat intrinsic factor and human transcobalamin I

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Biomarkers of cobalamin (vitamin B-12) status in the epidemiologic setting: a critical overview of context, applications, and performance characteristics of cobalamin, methylmalonic acid, and holotranscobalamin II

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Holotranscobalamin and methylmalonic acid as prognostic markers following an acute myocardial infarction

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Diagnosis and treatment of vitamin B12 deficiency--an update

27 September 2017

1 reference

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Facts and recommendations about total homocysteine determinations: an expert opinion

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Staging vitamin B-12 (cobalamin) status in vegetarians

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Cobalamin Analogues Are Present in Human Plasma and Can Mask Cobalamin Deficiency because Current Radioisotope Dilution Assays Are Not Specific for True Cobalamin

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Polymorphism of human transcobalamin II: substitution of proline and/or glutamine residues by arginine

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Cobalamin (vitamin B12) and holotranscobalamin changes in plasma and liver tissue in alcoholics with liver disease

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Assessment of vitamin B(12) absorption based on the accumulation of orally administered cyanocobalamin on transcobalamin.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Utility of measuring vitamin B12 and its active fraction, holotranscobalamin, in neurological vitamin B12 deficiency syndromes

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

The TCN2 776CNG polymorphism correlates with vitamin B(12) cellular delivery in healthy adult populations

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Daily intake of 4 to 7 microg dietary vitamin B-12 is associated with steady concentrations of vitamin B-12-related biomarkers in a healthy young population

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Metabolic signs of vitamin B(12) deficiency in humans: computational model and its implications for diagnostics.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Determination of serum holotranscobalamin concentrations with the AxSYM active B(12) assay: cut-off point evaluation in the clinical laboratory.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

A new principle for measurement of cobalamin and corrinoids, used for studies of cobalamin analogs on serum haptocorrin.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Active B12: a rapid, automated assay for holotranscobalamin on the Abbott AxSYM analyzer

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Holotranscobalamin in laboratory diagnosis of cobalamin deficiency compared to total cobalamin and methylmalonic acid

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Longitudinal study of the effect of pregnancy on maternal and fetal cobalamin status in healthy women and their offspring

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Holo-transcobalamin is an indicator of vitamin B-12 absorption in healthy adults with adequate vitamin B-12 status.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Detection of Vitamin B12 Deficiency in Older People by Measuring Vitamin B12 or the Active Fraction of Vitamin B12, Holotranscobalamin

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Plasma holotranscobalamin compared with plasma cobalamins for assessment of vitamin B12 absorption; optimisation of a non-radioactive vitamin B12 absorption test (CobaSorb).

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Macrophage serum markers in pneumococcal bacteremia: Prediction of survival by soluble CD163*

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Measurement of total vitamin B12 and holotranscobalamin, singly and in combination, in screening for metabolic vitamin B12 deficiency

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Holotranscobalamin and total transcobalamin in human plasma: determination, determinants, and reference values in healthy adults

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Circadian variation of holo-transcobalamin (holo-TC) and related markers

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Evaluation of the technical performance of novel holotranscobalamin (holoTC) assays in a multicenter European demonstration project

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Vitamin B12 deficiency is the dominant nutritional cause of hyperhomocysteinemia in a folic acid-fortified population

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Holotranscobalamin--a first choice assay for diagnosing early vitamin B deficiency?

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

The binding properties of the human receptor for the cellular uptake of vitamin B12.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Functional vitamin B12 deficiency and determination of holotranscobalamin in populations at risk

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Vitamin B-12 status, particularly holotranscobalamin II and methylmalonic acid concentrations, and hyperhomocysteinemia in vegetarians.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

RIA for serum holo-transcobalamin: method evaluation in the clinical laboratory and reference interval

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Holo-transcobalamin is an early marker of changes in cobalamin homeostasis. A randomized placebo-controlled study.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

High serum cobalamin levels in the clinical setting--clinical associations and holo-transcobalamin changes

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3127504

Depletion of serum holotranscobalamin II. An early sign of negative vitamin B12 balance

28 November 2018

1 reference

12 December 2020

Measurement of vitamin B12-binding proteins of plasma. I. Technique

1 reference

12 December 2020

Transcobalamin deficiency caused by compound heterozygosity for two novel mutations in the TCN2 gene: a study of two affected siblings, their brother, and their parents

1 reference

12 December 2020

Holotranscobalamin as an indicator of dietary vitamin B12 deficiency

1 reference

12 December 2020

Holotranscobalamin - a sensitive marker of cobalamin malabsorption

1 reference

12 December 2020

Holotranscobalamin remains unchanged during pregnancy. Longitudinal changes of cobalamins and their binding proteins during pregnancy and postpartum

1 reference

12 December 2020

Circulating antibody to transcobalamin II causing retention of vitamin B12 in the blood

1 reference

12 December 2020

Characterization of the particulate and soluble acceptor for transcobalamin II from human placenta and rabbit liver

1 reference

12 December 2020

Quantification of holo-transcobalamin, a marker of vitamin B12 deficiency

1 reference

12 December 2020

Turnover in humans of iodine- and cobalamin-labeled transcobalamin I and of iodine-labeled albumin

1 reference

12 December 2020

Application of a simple immunoadsorption assay for the measurement of saturated and unsaturated transcobalamin II and R-binders

1 reference

12 December 2020

Direct assay for cobalamin bound to transcobalamin (holo-transcobalamin) in serum

1 reference

12 December 2020

Changes in basal and postmethionine load concentrations of total homocysteine and cystathionine after B vitamin intervention

1 reference

12 December 2020

Transcobalamin I and other Human R-Binders: Purification, Structural, Spectral and Physiological Studies

1 reference

12 December 2020

Antibody to transcobalamin II and B12 binding capacity in patients treated with hydroxocobalamin

1 reference

12 December 2020

R-binder deficiency. A clinically benign cause of cobalamin pseudodeficiency

1 reference

12 December 2020

Measurement of transcobalamin by ELISA

1 reference

12 December 2020

Nonradioactive vitamin B12 absorption test evaluated in controls and in patients with inherited malabsorption of vitamin B12

1 reference

12 December 2020

Renal impairment compromises the use of total homocysteine and methylmalonic acid but not total vitamin B12 and holotranscobalamin in screening for vitamin B12 deficiency in the aged

1 reference

12 December 2020

Application of heparin-conjugated Sepharose for the measurement of cobalamin-saturated and unsaturated transcobalamin II

1 reference

12 December 2020

Plasma Clearance of57Cobalt-Labelled Vitamin B12Bound in Vitro and in Vivo to Transcobalamin I and II

1 reference

12 December 2020

Unsaturated and cobalamin saturated transcobalamin I and II in normal human plasma

1 reference

12 December 2020

Glycosylation independent measurement of the cobalamin binding protein haptocorrin

1 reference

12 December 2020

Identifiers

DOI

10.3945/AJCN.111.013458

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21593496 AND SRC:MED&resulttype=core&format=json

release_22bqcz7ovrdnxeq57gpc5luzoq

1 February 2020

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/22bqcz7ovrdnxeq57gpc5luzoq

24 November 2022

mapped directly with Wikidata item

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2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:21593496 AND SRC:MED&resulttype=core&format=json

1 February 2020

PubMed publication ID

21593496

2 references