Structural basis of microtubule severing by the hereditary spastic paraplegia protein spastin (Q24597228)

hereditary spastic paraplegia

GOA release 2020-03-11

1 reference

Antonina Roll-Mecak

1

0 references

Ronald Vale

series ordinal

2

object named as

Ronald D Vale

0 references

language of work or name

English

0 references

publication date

17 January 2008

0 references

published in

Nature

0 references

volume

451

0 references

issue

7176

0 references

page(s)

363-7

0 references

cites work

Recognition of C-terminal amino acids in tubulin by pore loops in Spastin is important for microtubule severing

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Human spastin has multiple microtubule-related functions

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Structural and mechanistic studies of VPS4 proteins

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Linking axonal degeneration to microtubule remodeling by Spastin-mediated microtubule severing

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Drosophila spastin regulates synaptic microtubule networks and is required for normal motor function

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Determination of domain structure of proteins from X-ray solution scattering

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Structure of the ATP-dependent oligomerization domain of N-ethylmaleimide sensitive factor complexed with ATP

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Spectrum of SPG4 mutations in autosomal dominant spastic paraplegia

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Spastin, a new AAA protein, is altered in the most frequent form of autosomal dominant spastic paraplegia

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Identification of katanin, an ATPase that severs and disassembles stable microtubules

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Three microtubule severing enzymes contribute to the "Pacman-flux" machinery that moves chromosomes

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Visualizing the ATPase cycle in a protein disaggregating machine: structural basis for substrate binding by ClpB

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

The Drosophila homologue of the hereditary spastic paraplegia protein, spastin, severs and disassembles microtubules

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Sculpting the proteome with AAA( ) proteases and disassembly machines.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Phylogenetic analysis of AAA proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

The Caenorhabditis elegans microtubule-severing complex MEI-1/MEI-2 katanin interacts differently with two superficially redundant beta-tubulin isotypes

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

MEI-1/MEI-2 katanin-like microtubule severing activity is required for Caenorhabditis elegans meiosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

A rat monoclonal antibody reacting specifically with the tyrosylated form of alpha-tubulin. I. Biochemical characterization, effects on microtubule polymerization in vitro, and microtubule polymerization and organization in vivo

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Making more microtubules by severing: a common theme of noncentrosomal microtubule arrays?

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Role of the processing pore of the ClpX AAA ATPase in the recognition and engagement of specific protein substrates

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Microtubule disassembly by ATP-dependent oligomerization of the AAA enzyme katanin

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

The C. elegans homologue of the spastic paraplegia protein, spastin, disassembles microtubules

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

A mutation of spastin is responsible for swellings and impairment of transport in a region of axon characterized by changes in microtubule composition.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

The microtubule-severing protein Spastin is essential for axon outgrowth in the zebrafish embryo

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Loops in the central channel of ClpA chaperone mediate protein binding, unfolding, and translocation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

The hereditary spastic paraplegia gene, spastin, regulates microtubule stability to modulate synaptic structure and function.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Substrate recognition by the AAA chaperone ClpB.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

A katanin-like protein regulates normal cell wall biosynthesis and cell elongation

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Distinct populations of microtubules: tyrosinated and nontyrosinated alpha tubulin are distributed differently in vivo

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2882799

Tyrosination state of free tubulin subunits and tubulin disassembled from microtubules of rat brain tissue

28 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18202664

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Kinesin walks hand-over-hand

1 reference

Crossref

https://api.crossref.org/works/10.1038/NATURE06482

inferred from DOI database lookup

7 January 2021

based on heuristic

Identifiers

DOI

10.1038/NATURE06482

1 reference

Dimensions Publication ID

1029072052

0 references

1 reference

1 reference

PubMed publication ID

18202664

1 reference