Structure of the human BK channel Ca2 -activation apparatus at 3.0 A resolution (Q24595712)

19 October 2023

3

Alexander R Pico

Alexander R

Pico

1 reference

19 October 2023

Manuel D Leonetti

2

Manuel D

Leonetti

1 reference

19 October 2023

Peng Yuan

1

Peng

Yuan

1 reference

20508092

19 October 2023

Yichun Hsiung

series ordinal

4

author given names

Yichun

author last names

Hsiung

1 reference

20508092

The RCK2 domain of the human BKCa channel is a calcium sensor

19 October 2023

language of work or name

English

0 references

publication date

9 July 2010

0 references

published in

Science

0 references

volume

329

0 references

issue

5988

0 references

page(s)

182-6

0 references

cites work

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

A noncanonical SH3 domain binding motif links BK channels to the actin cytoskeleton via the SH3 adapter cortactin

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Gating mechanism of BK (Slo1) channels: so near, yet so far

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Large conductance voltage- and calcium-dependent K channel, a distinct member of voltage-dependent ion channels with seven N-terminal transmembrane segments (S0-S6), an extracellular N terminus, and an intracellular (S9-S10) C terminus

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

A novel calcium-sensing domain in the BK channel

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Atomic structure of a voltage-dependent K channel in a lipid membrane-like environment

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Crystal structure and mechanism of a calcium-gated potassium channel

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Structure of the RCK domain from the E. coli K channel and demonstration of its presence in the human BK channel

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Shape complementarity at protein/protein interfaces

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Crystal structures of a ligand-free MthK gating ring: insights into the ligand gating mechanism of K channels

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Structure of the BK potassium channel in a lipid membrane from electron cryomicroscopy

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Activation of Slo1 BK channels by Mg2 coordinated between the voltage sensor and RCK1 domains

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Modulation of the conductance-voltage relationship of the BK Ca channel by mutations at the putative flexible interface between two RCK domains.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

High-conductance potassium channels of the SLO family

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Large conductance Ca2 -activated K (BK) channel: activation by Ca2 and voltage

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Three methionine residues located within the regulator of conductance for K (RCK) domains confer oxidative sensitivity to large-conductance Ca2 -activated K channels.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Homology modeling identifies C-terminal residues that contribute to the Ca2 sensitivity of a BKCa channel

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Divalent cation sensitivity of BK channel activation supports the existence of three distinct binding sites.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Mapping the BKCa channel's "Ca2 bowl": side-chains essential for Ca2 sensing

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Elimination of the BK(Ca) channel's high-affinity Ca(2 ) sensitivity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Protein kinases: tuners of the BKCa channel in smooth muscle.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Alternative splicing of potassium channels: a dynamic switch of cellular excitability.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Ca2 -binding activity of a COOH-terminal fragment of the Drosophila BK channel involved in Ca2 -dependent activation

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Mechanisms of hair cell tuning

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

High-conductance calcium-activated potassium channels; structure, pharmacology, and function

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Modulation of the conductance-voltage relationship of the BK(Ca) channel by shortening the cytosolic loop connecting two RCK domains

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Reciprocal regulation of the Ca2 and H sensitivity in the SLO1 BK channel conferred by the RCK1 domain

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Calcium-sensitive potassium channelopathy in human epilepsy and paroxysmal movement disorder

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Calcium sensitivity of BK-type KCa channels determined by a separable domain.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Hydrophobic interface between two regulators of K conductance domains critical for calcium-dependent activation of large conductance Ca2 -activated K channels.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Structures of the MthK RCK domain and the effect of Ca2 on gating ring stability

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Multiple regulatory sites in large-conductance calcium-activated potassium channels.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Mechanism of magnesium activation of calcium-activated potassium channels.

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Vasoregulation by the beta1 subunit of the calcium-activated potassium channel

28 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3022345

Beta1-subunit of the Ca2 -activated K channel regulates contractile activity of mouse urinary bladder smooth muscle

28 November 2018

1 reference

https://pubmed.ncbi.nlm.nih.gov/20508092

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Functional colocalization of calcium and calcium-gated potassium channels in control of transmitter release

1 reference

https://pubmed.ncbi.nlm.nih.gov/20508092

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Relaxation of arterial smooth muscle by calcium sparks

1 reference

https://pubmed.ncbi.nlm.nih.gov/20508092

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1126/SCIENCE.1190414

1 reference

release_mej7lmokizc5hn544mpi3jr7ia

0 references

0 references

641681

1 reference

1 reference

641681

20508092

1 reference