Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase (Q24595502)

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16 January 2020

title

Iron-catalysed oxidation intermediates captured in a DNA repair dioxygenase (English)

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16 January 2020

1

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16 January 2020

Xing Jian

7

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16 January 2020

author name string

Guifang Jia

2

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16 January 2020

Guanhua Hou

3

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16 January 2020

Qing Dai

4

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16 January 2020

Wen Zhang

5

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16 January 2020

Guanqun Zheng

6

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16 January 2020

Cai-Guang Yang

8

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16 January 2020

Qiang Cui

9

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16 January 2020

Chuan He

10

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16 January 2020

language of work or name

English

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publication date

1 November 2010

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16 January 2020

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16 January 2020

volume

468

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16 January 2020

issue

7321

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16 January 2020

page(s)

330-333

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Crystal structure of the FTO protein reveals basis for its substrate specificity

16 January 2020

cites work

1 reference

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A non-heme iron-mediated chemical demethylation in DNA and RNA

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058853

Oxidative demethylation of 3-methylthymine and 3-methyluracil in single-stranded DNA and RNA by mouse and human FTO

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058853

Human AlkB homolog 1 is a mitochondrial protein that demethylates 3-methylcytosine in DNA and RNA

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058853

Crystal structures of DNA/RNA repair enzymes AlkB and ABH2 bound to dsDNA

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058853

The obesity-associated FTO gene encodes a 2-oxoglutarate-dependent nucleic acid demethylase

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058853

A common variant in the FTO gene is associated with body mass index and predisposes to childhood and adult obesity

24 March 2017

1 reference

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Human ABH3 structure and key residues for oxidative demethylation to reverse DNA/RNA damage

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058853

Repair deficient mice reveal mABH2 as the primary oxidative demethylase for repairing 1meA and 3meC lesions in DNA

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058853

Mutagenesis, genotoxicity, and repair of 1-methyladenine, 3-alkylcytosines, 1-methylguanine, and 3-methylthymine in alkB Escherichia coli

24 March 2017

1 reference

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Structural and Mutational Analysis of Escherichia coli AlkB Provides Insight into Substrate Specificity and DNA Damage Searching

24 March 2017

1 reference

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Encounter and extrusion of an intrahelical lesion by a DNA repair enzyme

24 March 2017

1 reference

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Enzymological and structural studies of the mechanism of promiscuous substrate recognition by the oxidative DNA repair enzyme AlkB

24 March 2017

1 reference

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Crystal Structures of Fe2 Dioxygenase Superoxo, Alkylperoxo, and Bound Product Intermediates

24 March 2017

1 reference

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The catalytic pathway of cytochrome p450cam at atomic resolution

24 March 2017

1 reference

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The reaction cycle of isopenicillin N synthase observed by X-ray diffraction

24 March 2017

1 reference

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Coot: model-building tools for molecular graphics

24 March 2017

1 reference

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The CCP4 suite: programs for protein crystallography

24 March 2017

1 reference

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PHENIX: building new software for automated crystallographic structure determination

24 March 2017

1 reference

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Pushing the boundaries of molecular replacement with maximum likelihood

24 March 2017

1 reference

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Regulation of histone methylation by demethylimination and demethylation

24 March 2017

1 reference

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Crystal structures of catalytic complexes of the oxidative DNA/RNA repair enzyme AlkB

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058853

AlkB reverses etheno DNA lesions caused by lipid oxidation in vitro and in vivo

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058853

DNA glycosylase recognition and catalysis

24 March 2017

1 reference

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Oxidative demethylation by Escherichia coli AlkB directly reverts DNA base damage

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058853

Base-excision repair of oxidative DNA damage

24 March 2017

1 reference

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Human and bacterial oxidative demethylases repair alkylation damage in both RNA and DNA

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058853

AlkB-mediated oxidative demethylation reverses DNA damage in Escherichia coli

7 April 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058853

Versatility of biological non-heme Fe(II) centers in oxygen activation reactions.

7 April 2017

1 reference

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The intricate structural chemistry of base excision repair machinery: implications for DNA damage recognition, removal, and repair.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058853

Direct repair of the exocyclic DNA adduct 1,N6-ethenoadenine by the DNA repair AlkB proteins

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3058853

Repair of 3-methylthymine and 1-methylguanine lesions by bacterial and human AlkB proteins

27 September 2017

1 reference

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Structural and mechanistic studies on 2-oxoglutarate-dependent oxygenases and related enzymes

27 September 2017

1 reference

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Preparation and characterization of the native iron(II)-containing DNA repair AlkB protein directly from Escherichia coli

27 September 2017

1 reference

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Demethylation of 3-methylthymine in DNA by bacterial and human DNA dioxygenases

28 November 2018

1 reference

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Probing the structure and function of the Escherichia coli DNA alkylation repair AlkB protein through chemical cross-linking.

28 November 2018

1 reference

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28 November 2018

Identifiers

DOI

10.1038/NATURE09497

1 reference

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Dimensions Publication ID

16 January 2020

0 references

1 reference

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16 January 2020

PubMed publication ID

21068844

1 reference