PRDM9 variation strongly influences recombination hot-spot activity and meiotic instability in humans (Q24595214)

6

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author name string

Ingrid L Berg

1

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Rita Neumann

2

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Kwan-Wood G Lam

3

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Shriparna Sarbajna

4

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Alec J Jeffreys

Prdm9 controls activation of mammalian recombination hotspots

7

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language of work or name

English

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publication date

October 2010

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published in

Nature Genetics

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volume

42

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issue

10

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page(s)

859-63

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cites work

1 reference

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24 March 2017

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A histone H3 methyltransferase controls epigenetic events required for meiotic prophase

24 March 2017

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Origins and functional impact of copy number variation in the human genome

24 March 2017

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Linkage disequilibrium in the human genome

24 March 2017

1 reference

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DNA recognition by Cys2His2 zinc finger proteins

7 April 2017

1 reference

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Mammalian recombination hot spots: properties, control and evolution.

7 April 2017

1 reference

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Drive against hotspot motifs in primates implicates the PRDM9 gene in meiotic recombination

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=3092422

PRDM9 is a major determinant of meiotic recombination hotspots in humans and mice

27 September 2017

1 reference

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Genetic analysis of variation in human meiotic recombination

27 September 2017

1 reference

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The rise and fall of a human recombination hot spot

27 September 2017

1 reference

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Sperm cross-over activity in regions of the human genome showing extreme breakdown of marker association

27 September 2017

1 reference

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Sequence variants in the RNF212 gene associate with genome-wide recombination rate

27 September 2017

1 reference

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Germline rates of de novo meiotic deletions and duplications causing several genomic disorders

27 September 2017

1 reference

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A chromosomal rearrangement hotspot can be identified from population genetic variation and is coincident with a hotspot for allelic recombination

27 September 2017

1 reference

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Two modes of germline instability at human minisatellite MS1 (locus D1S7): complex rearrangements and paradoxical hyperdeletion.

27 September 2017

1 reference

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Tightly clustered 11q23 and 22q11 breakpoints permit PCR-based detection of the recurrent constitutional t(11;22).

27 September 2017

1 reference

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High resolution analysis of haplotype diversity and meiotic crossover in the human TAP2 recombination hotspot

27 September 2017

1 reference

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Genetic variation affects de novo translocation frequency.

27 September 2017

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Influences of array size and homogeneity on minisatellite mutation.

30 May 2018

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A common sequence motif associated with recombination hot spots and genome instability in humans

30 May 2018

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Reciprocal crossover asymmetry and meiotic drive in a human recombination hot spot.

21 January 2018

1 reference

Factors influencing recombination frequency and distribution in a human meiotic crossover hotspot.

21 January 2018

1 reference

Polymorphism in the activity of human crossover hotspots independent of local DNA sequence variation.

21 January 2018

1 reference

Extremely complex repeat shuffling during germline mutation at human minisatellite B6.7.

21 January 2018

1 reference

Complex gene conversion events in germline mutation at human minisatellites

21 January 2018

1 reference

Minisatellite mutation rate variation associated with a flanking DNA sequence polymorphism

21 January 2018

1 reference

Unexpectedly high rate of de novo constitutional t(11;22) translocations in sperm from normal males

21 January 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20818382

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Charcot-Marie-Tooth type 1A duplication appears to arise from recombination at repeat sequences flanking the 1.5 Mb monomer unit

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20818382

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

High-resolution mapping of crossovers in human sperm defines a minisatellite-associated recombination hotspot

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/20818382

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1038/NG.658

1 reference

Dimensions Publication ID

1011264677

0 references

1 reference

1 reference

PubMed publication ID

20818382

1 reference