Gene regulation by temperature-sensitive p53 mutants: identification of p53 response genes (Q24562795)

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R Talbott

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B R Seizinger

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N Kley

Proceedings of the National Academy of Sciences of the United States of America

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language of work or name

English

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publication date

25 October 1994

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published in

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volume

91

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issue

22

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page(s)

10640-4

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cites work

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WAF1, a potential mediator of p53 tumor suppression

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Identification of p53 as a sequence-specific DNA-binding protein

24 March 2017

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Repression of the interleukin 6 gene promoter by p53 and the retinoblastoma susceptibility gene product

24 March 2017

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Oncogenic forms of p53 inhibit p53-regulated gene expression

24 March 2017

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Definition of a consensus binding site for p53

24 March 2017

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Suppression of human colorectal carcinoma cell growth by wild-type p53

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A mammalian cell cycle checkpoint pathway utilizing p53 and GADD45 is defective in ataxia-telangiectasia

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The p53 activation domain binds the TATA box-binding polypeptide in Holo-TFIID, and a neighboring p53 domain inhibits transcription

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Sequence-specific transcriptional activation is essential for growth suppression by p53.

27 September 2017

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p53 functions as a cell cycle control protein in osteosarcomas

27 September 2017

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27 September 2017

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Wild-type p53 can down-modulate the activity of various promoters

27 September 2017

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A gene expression screen

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The MCK enhancer contains a p53 responsive element

27 September 2017

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A transcriptionally active DNA-binding site for human p53 protein complexes

27 September 2017

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Induction of apoptosis by wild-type p53 in a human colon tumor-derived cell line.

27 September 2017

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Repression of the basal c-fos promoter by wild-type p53

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45077

p53 function and dysfunction

27 September 2017

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45077

p53: a transdominant regulator of transcription whose function is ablated by mutations occurring in human cancer

27 September 2017

1 reference

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Specific repression of TATA-mediated but not initiator-mediated transcription by wild-type p53.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45077

Wild-type p53 mediates positive regulation of gene expression through a specific DNA sequence element

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=45077

Thyroid hormone-induced gene expression changes in the developing frog limb

30 May 2018

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Wild-type p53 activates transcription in vitro

30 May 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7938006

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Altered cell cycle arrest and gene amplification potential accompany loss of wild-type p53

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7938006

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Direct interaction between the transcriptional activation domain of human p53 and the TATA box-binding protein

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/7938006