Discovery of FabH/FabF inhibitors from natural products (Q24538774)

6 July 2017

title

Discovery of FabH/FabF inhibitors from natural products (English)

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6 July 2017

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Katherine Young

1

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6 July 2017

Hiranthi Jayasuriya

2

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6 July 2017

John G Ondeyka

3

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6 July 2017

Kithsiri Herath

4

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6 July 2017

Chaowei Zhang

5

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6 July 2017

Srinivas Kodali

6

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6 July 2017

Andrew Galgoci

7

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6 July 2017

Ronald Painter

8

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6 July 2017

Vickie Brown-Driver

9

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6 July 2017

Robert Yamamoto

10

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6 July 2017

Lynn L Silver

11

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6 July 2017

Yingcong Zheng

12

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6 July 2017

Judith I Ventura

13

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6 July 2017

Janet Sigmund

14

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6 July 2017

Sookhee Ha

15

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6 July 2017

Angela Basilio

16

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6 July 2017

Francisca Vicente

17

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6 July 2017

José Rubén Tormo

18

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6 July 2017

Fernando Pelaez

19

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6 July 2017

Phil Youngman

20

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6 July 2017

Doris Cully

21

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6 July 2017

John F Barrett

22

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6 July 2017

Dennis Schmatz

23

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6 July 2017

Sheo B Singh

24

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6 July 2017

Jun Wang

25

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6 July 2017

language of work or name

English

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publication date

1 February 2006

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Antimicrobial Agents and Chemotherapy

6 July 2017

published in

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6 July 2017

volume

50

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6 July 2017

issue

2

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6 July 2017

page(s)

519-526

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Crystal structure and substrate specificity of the beta-ketoacyl-acyl carrier protein synthase III (FabH) from Staphylococcus aureus

6 July 2017

cites work

1 reference

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Staphylococcus aureus RNAIII and the endoribonuclease III coordinately regulate spa gene expression

24 March 2017

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1,2-dithiole-3-ones as potent inhibitors of the bacterial 3-ketoacyl acyl carrier protein synthase III (FabH)

24 March 2017

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Essential Bacillus subtilis genes

24 March 2017

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24 March 2017

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THE STRUCTURAL BIOLOGY OF TYPE II FATTY ACID BIOSYNTHESIS

24 March 2017

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First X-ray cocrystal structure of a bacterial FabH condensing enzyme and a small molecule inhibitor achieved using rational design and homology modeling

24 March 2017

1 reference

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Inhibition of beta-ketoacyl-acyl carrier protein synthases by thiolactomycin and cerulenin. Structure and mechanism

24 March 2017

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Anthrabenzoxocinones from Streptomyces sp. as liver X receptor ligands and antibacterial agents

24 March 2017

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Structural and functional organization of the animal fatty acid synthase

24 March 2017

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Thiolactomycin and related analogues as novel anti-mycobacterial agents targeting KasA and KasB condensing enzymes in Mycobacterium tuberculosis

24 March 2017

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Global transposon mutagenesis and a minimal Mycoplasma genome

24 March 2017

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inhA, a gene encoding a target for isoniazid and ethionamide in Mycobacterium tuberculosis

7 April 2017

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Discovery of bacterial fatty acid synthase inhibitors from a Phoma species as antimicrobial agents using a new antisense-based strategy.

7 April 2017

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Application of a flexible synthesis of (5R)-thiolactomycin to develop new inhibitors of type I fatty acid synthase.

27 September 2017

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Determination of selectivity and efficacy of fatty acid synthesis inhibitors

27 September 2017

1 reference

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Fatty acid biosynthesis as a target for novel antibacterials

27 September 2017

1 reference

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Acetylene-based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme

27 September 2017

1 reference

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Biphenyl-based analogues of thiolactomycin, active against Mycobacterium tuberculosis mtFabH fatty acid condensing enzyme

27 September 2017

1 reference

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RNA processing and degradation in Bacillus subtilis

27 September 2017

1 reference

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The application of computational methods to explore the diversity and structure of bacterial fatty acid synthase

27 September 2017

1 reference

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A genome-wide strategy for the identification of essential genes in Staphylococcus aureus

27 September 2017

1 reference

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Antisense RNAs in bacteria and their genetic elements

27 September 2017

1 reference

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Lipid biosynthesis as a target for antibacterial agents

27 September 2017

1 reference

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Efflux-mediated drug resistance in Gram-positive bacteria

27 September 2017

1 reference

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Identification of critical staphylococcal genes using conditional phenotypes generated by antisense RNA.

27 September 2017

1 reference

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Bacterial fatty acid biosynthesis: targets for antibacterial drug discovery

27 September 2017

1 reference

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Identification, substrate specificity, and inhibition of the Streptococcus pneumoniae beta-ketoacyl-acyl carrier protein synthase III (FabH).

27 September 2017

1 reference

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Beta-ketoacyl acyl carrier protein synthase III (FabH) is essential for fatty acid biosynthesis in Streptomyces coelicolor A3(2).

27 September 2017

1 reference

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Response of Bacillus subtilis to cerulenin and acquisition of resistance

27 September 2017

1 reference

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Messenger RNA stability and its role in control of gene expression in bacteria and phages

27 September 2017

1 reference

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Leakage of periplasmic enzymes from envA1 strains of Escherichia coli

27 September 2017

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Overproduction of beta-ketoacyl-acyl carrier protein synthase I imparts thiolactomycin resistance to Escherichia coli K-12

27 September 2017

1 reference

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Genome-wide operon prediction in Staphylococcus aureus

27 September 2017

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β-Ketoacyl-Acyl Carrier Protein Synthase III (FabH) Is Essential for Bacterial Fatty Acid Synthesis

27 September 2017

1 reference

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Broad spectrum antimicrobial biocides target the FabI component of fatty acid synthesis

30 May 2018

1 reference

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The carboxyl-terminal anchorage domain of the turkey beta 1-adrenergic receptor is encoded by an alternatively spliced exon

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366929

Thiolactomycin, a new antibiotic. III. In vitro antibacterial activity.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366929

beta-Ketoacyl-ACP synthase I of Escherichia coli: nucleotide sequence of the fabB gene and identification of the cerulenin binding residue.

30 May 2018

1 reference

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Antitubercular agents. Part 2: new thiolactomycin analogues active against Mycobacterium tuberculosis

19 June 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366929

Validation of antibacterial mechanism of action using regulated antisense RNA expression in Staphylococcus aureus

29 November 2018

1 reference

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Analogues of thiolactomycin as potential anti-malarial and anti-trypanosomal agents

29 November 2018

1 reference

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Identification and molecular characterization of the beta-ketoacyl-[acyl carrier protein] synthase component of the Arabidopsis mitochondrial fatty acid synthase.

29 November 2018

1 reference

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Discovery of a small molecule that inhibits cell division by blocking FtsZ, a novel therapeutic target of antibiotics

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1366929

Analogues of thiolactomycin: potential drugs with enhanced anti-mycobacterial activity

29 November 2018

1 reference

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Synthesis and structure-activity relationships of thiotetronic acid analogues of thiolactomycin.

29 November 2018

1 reference

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Multidrug resistance in Gram-negative bacteria.

29 November 2018

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Thiotetromycin, a new antibiotic. Taxonomy, production, isolation, and physicochemical and biological properties.

29 November 2018

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Purification and properties of a new bacillus subtilis RNA processing enzyme. Cleavage of phage SP82 mRNA and Bacillus subtilis precursor rRNA

29 November 2018

1 reference

PubMed

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12 December 2020

inferred from PubMed ID database lookup

Isolation and structure of antibiotic U-68,204, a new thiolactone

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16436705

12 December 2020

inferred from PubMed ID database lookup

STUDIES ON CERULENIN. IV. BIOLOGICAL CHARACTERISTICS OF CERULENIN

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/16436705

12 December 2020

inferred from PubMed ID database lookup

A new member of the class of antibiotics with thiotetronic acid structure isolated fromStreptomyces olivaceus Tü 3010

1 reference

Crossref

https://api.crossref.org/works/10.1128/AAC.50.2.519-526.2006

7 January 2021

inferred from DOI database lookup

Identifiers

DOI

10.1128/AAC.50.2.519-526.2006

1 reference

release_gergwss7c5abhcscpijrz56dcy

6 July 2017

Fatcat ID

1 reference

Fatcat

https://api.fatcat.wiki/v0/release/gergwss7c5abhcscpijrz56dcy

24 November 2022

mapped directly with Wikidata item

PMC publication ID

1366929

1 reference

6 July 2017

1 reference