Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans (Q24536711)

5 July 2017

title

Genetic variation of folate-mediated one-carbon transfer pathway predicts susceptibility to choline deficiency in humans (English)

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5 July 2017

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4

Steven H Zeisel

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5 July 2017

Martin Kohlmeier

1

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5 July 2017

Kerry-Ann da Costa

series ordinal

2

1 reference

5 July 2017

Leslie M Fischer

series ordinal

3

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5 July 2017

language of work or name

English

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publication date

18 October 2005

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Proceedings of the National Academy of Sciences of the United States of America

5 July 2017

published in

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5 July 2017

volume

102

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5 July 2017

issue

44

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5 July 2017

page(s)

16025-16030

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A Polymorphism, R653Q, in the Trifunctional Enzyme Methylenetetrahydrofolate Dehydrogenase/Methenyltetrahydrofolate Cyclohydrolase/Formyltetrahydrofolate Synthetase Is a Maternal Genetic Risk Factor for Neural Tube Defects

5 July 2017

cites work

1 reference

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Phosphatidylethanolamine N-methyltransferase from liver

24 March 2017

1 reference

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Betaine–Homocysteine Methyltransferase Expression in Porcine and Human Tissues and Chromosomal Localization of the Human Gene

24 March 2017

1 reference

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The active synthesis of phosphatidylcholine is required for very low density lipoprotein secretion from rat hepatocytes

24 March 2017

1 reference

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Choline, an essential nutrient for humans

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1276051

Choline deficiency in mice and humans is associated with increased plasma homocysteine concentration after a methionine load

24 March 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1276051

Regulation of choline deficiency apoptosis by epidermal growth factor in CWSV-1 rat hepatocytes

27 September 2017

1 reference

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Periconceptional dietary intake of choline and betaine and neural tube defects in offspring

27 September 2017

1 reference

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Elevated serum creatine phosphokinase in choline-deficient humans: mechanistic studies in C2C12 mouse myoblasts

27 September 2017

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High-level multiplex genotyping of polymorphisms involved in folate or homocysteine metabolism by matrix-assisted laser desorption/ionization mass spectrometry

27 September 2017

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Concentrations of choline-containing compounds and betaine in common foods

27 September 2017

1 reference

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Perturbations in choline metabolism cause neural tube defects in mouse embryos in vitro

27 September 2017

2 references

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27 September 2017

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Statistics notes. The odds ratio

21 January 2018

1 reference

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Folate metabolism and requirements

27 September 2017

1 reference

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Molecular genetic aspects of hyperhomocysteinemia and its relation to folic acid.

27 September 2017

1 reference

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Periconceptional vitamin use, dietary folate, and the occurrence of neural tube defects

27 September 2017

2 references

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27 September 2017

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Rat and human mammary tissue can synthesize choline moiety via the methylation of phosphatidylethanolamine

21 January 2018

1 reference

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Effect of choline deficiency on S-adenosylmethionine and methionine concentrations in rat liver

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1276051

Choline deficiency induces apoptosis in SV40-immortalized CWSV-1 rat hepatocytes in culture

27 September 2017

1 reference

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Developmental changes in the activity of phosphatidylethanolamine N-methyltransferases in rat brain

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1276051

Estradiol activates methylating enzyme(s) involved in the conversion of phosphatidylethanolamine to phosphatidylcholine in rat pituitary membranes

30 May 2018

1 reference

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Choline antagonism of methotrexate liver toxicity in the rat.

30 May 2018

1 reference

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Choline and human nutrition.

30 May 2018

1 reference

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Human betaine-homocysteine methyltransferase is a zinc metalloenzyme

21 January 2018

1 reference

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Choline- and betaine-defined diets for use in clinical research and for the management of trimethylaminuria

21 January 2018

1 reference

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Inhibitors of choline uptake and metabolism cause developmental abnormalities in neurulating mouse embryos

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0504285102

Homocysteine-betaine interactions in a murine model of 5,10-methylenetetrahydrofolate reductase deficiency

21 January 2018

1 reference

https://api.crossref.org/works/10.1073/PNAS.0504285102

The methylenetetrahydrofolate reductase 677C->T polymorphism and dietary folate restriction affect plasma one-carbon metabolites and red blood cell folate concentrations and distribution in women

21 January 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1276051

Tracer-derived total and folate-dependent homocysteine remethylation and synthesis rates in humans indicate that serine is the main one-carbon donor

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1276051

Neither methionine nor nitrous oxide inactivation of methionine synthase affect the concentration of 5,10-methylenetetrahydrofolate in rat liver

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1276051

Primed, constant infusion with [2H3]serine allows in vivo kinetic measurement of serine turnover, homocysteine remethylation, and transsulfuration processes in human one-carbon metabolism.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1276051

Effects of choline deficiency and methotrexate treatment upon liver folate content and distribution

29 November 2018

1 reference

12 December 2020

Effects of choline deficiency and methotrexate treatment upon rat liver

1 reference

12 December 2020

Severe folate deficiency causes secondary depletion of choline and phosphocholine in rat liver

1 reference

12 December 2020

Homocysteine synthesis is elevated but total remethylation is unchanged by the methylenetetrahydrofolate reductase 677C->T polymorphism and by dietary folate restriction in young women

1 reference

12 December 2020

Head group specificity in the requirement of phosphatidylcholine biosynthesis for very low density lipoprotein secretion from cultured hepatocytes

1 reference

12 December 2020

Lactobacillus casei microbiological assay of folic acid derivatives in 96-well microtiter plates

1 reference

12 December 2020

Introduction of fast MR imaging in the assessment of hepatic steatosis

1 reference

12 December 2020

Distribution in healthy and coronary populations of the methylenetetrahydrofolate reductase (MTHFR) C677T mutation

1 reference

12 December 2020

Effect of methotrexate on homocysteine and other sulfur compounds in tissues of rats fed a normal or a defined, choline-deficient diet

1 reference

12 December 2020

Choline deficiency: a cause of hepatic steatosis during parenteral nutrition that can be reversed with intravenous choline supplementation

1 reference

12 December 2020

Effect of methotrexate on long-chain fatty acid metabolism in liver of rats fed a standard or a defined, choline-deficient diet

1 reference

12 December 2020

Plasma S-adenosylhomocysteine is a more sensitive indicator of cardiovascular disease than plasma homocysteine

1 reference

12 December 2020

Rapid high-performance liquid chromatographic assay for total homocysteine levels in human serum

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.0504285102

1 reference

release_bobpdz6fyzcwdisxr4ofjnxmte

5 July 2017

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1 reference

Fatcat

https://api.fatcat.wiki/v0/release/bobpdz6fyzcwdisxr4ofjnxmte

24 November 2022

mapped directly with Wikidata item

PMC publication ID

1276051

1 reference

5 July 2017

1 reference