The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin. (Q24535620)

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English	The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin.	scientific article

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12 November 2019

The histone deacetylase inhibitor SAHA arrests cancer cell growth, up-regulates thioredoxin-binding protein-2, and down-regulates thioredoxin (English)

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12 November 2019

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12 November 2019

Howard I. Scher

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Howard I Scher

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12 November 2019

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Lisa M Butler

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12 November 2019

Wei-Sheng Xu

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12 November 2019

Richard A Rifkind

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12 November 2019

Paul A Marks

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12 November 2019

Victoria M Richon

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12 November 2019

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20 August 2002

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12 November 2019

Proceedings of the National Academy of Sciences of the United States of America

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12 November 2019

99

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12 November 2019

18

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12 November 2019

11700-11705

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12 November 2019

Identification of HDAC10, a novel class II human histone deacetylase containing a leucine-rich domain

1 reference

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24 March 2017

Isolation and characterization of a novel class II histone deacetylase, HDAC10

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24 March 2017

Molecular cloning and characterization of a novel histone deacetylase HDAC10

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129332

24 March 2017

Histone deacetylase inhibitors induce remission in transgenic models of therapy-resistant acute promyelocytic leukemia

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24 March 2017

Cloning and characterization of a histone deacetylase, HDAC9

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24 March 2017

Histone deacetylase inhibitor selectively induces p21WAF1 expression and gene-associated histone acetylation

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24 March 2017

Transcriptional silencing and longevity protein Sir2 is an NAD-dependent histone deacetylase

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24 March 2017

Accurate transcription initiation by RNA polymerase II in a soluble extract from isolated mammalian nuclei

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24 March 2017

The silencing protein SIR2 and its homologs are NAD-dependent protein deacetylases

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129332

24 March 2017

Histone acetylation in chromatin structure and transcription

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129332

24 March 2017

The molecular biology of the CCAAT-binding factor NF-Y

1 reference

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24 March 2017

Identification of thioredoxin-binding protein-2/vitamin D(3) up-regulated protein 1 as a negative regulator of thioredoxin function and expression

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129332

24 March 2017

Isolation and characterization of a novel cDNA from HL-60 cells treated with 1,25-dihydroxyvitamin D-3

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24 March 2017

Isolation and characterization of mammalian HDAC10, a novel histone deacetylase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129332

24 March 2017

Physiological functions of thioredoxin and thioredoxin reductase

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129332

7 April 2017

Histone deacetylases and cancer: causes and therapies

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129332

27 September 2017

The histone deacetylase inhibitor suberoylanilide hydroxamic acid induces differentiation of human breast cancer cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129332

27 September 2017

Inhibition of transformed cell growth and induction of cellular differentiation by pyroxamide, an inhibitor of histone deacetylase

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129332

27 September 2017

The human histone deacetylase family

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27 September 2017

Suberoylanilide hydroxamic acid as a potential therapeutic agent for human breast cancer treatment

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27 September 2017

Transcriptional regulation of the MDR1 gene by histone acetyltransferase and deacetylase is mediated by NF-Y.

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27 September 2017

A class of hybrid polar inducers of transformed cell differentiation inhibits histone deacetylases.

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27 September 2017

A survey of 178 NF-Y binding CCAAT boxes

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27 September 2017

Histone Deacetylase Inhibitor Activates the WAF1/Cip1 Gene Promoter through the Sp1 Sites

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129332

27 September 2017

Second generation hybrid polar compounds are potent inducers of transformed cell differentiation.

1 reference

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27 September 2017

Dominant negative analogs of NF-YA.

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27 September 2017

Cell growth stimulation by the redox protein thioredoxin occurs by a novel helper mechanism

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129332

27 September 2017

The expression of a small fraction of cellular genes is changed in response to histone hyperacetylation.

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27 September 2017

Histone deacetylase inhibitors and retinoic acids inhibit growth of human neuroblastoma in vitro

1 reference

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30 May 2018

Anti-tumour activity in vitro and in vivo of selective differentiating agents containing hydroxamate

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30 May 2018

Transfection with human thioredoxin increases cell proliferation and a dominant-negative mutant thioredoxin reverses the transformed phenotype of human breast cancer cells

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=129332

30 May 2018

Sodium Butyrate Induces NIH3T3 Cells to Senescence-like State and Enhances Promoter Activity of p21WAF/CIP1in p53-Independent Manner

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21 January 2018

Transcriptional activity of the SHP-1 gene in MCF7 cells is differentially regulated by binding of NF-Y factor to two distinct CCAAT-elements

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https://api.crossref.org/works/10.1073/PNAS.182372299

21 January 2018

The histone deacetylase inhibitor, CBHA, inhibits growth of human neuroblastoma xenografts in vivo, alone and synergistically with all-trans retinoic acid.

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29 November 2018

Thioredoxin and thioredoxin reductase gene expression in human tumors and cell lines, and the effects of serum stimulation and hypoxia

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12 December 2020

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Thioredoxin, a gene found overexpressed in human cancer, inhibits apoptosis in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12189205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Histone deacetylase inhibition selectively alters the activity and expression of cell cycle proteins leading to specific chromatin acetylation and antiproliferative effects

1 reference

https://pubmed.ncbi.nlm.nih.gov/12189205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Chemoprevention of carcinogen-induced mammary tumorigenesis by the hybrid polar cytodifferentiation agent, suberanilohydroxamic acid (SAHA)

1 reference

https://pubmed.ncbi.nlm.nih.gov/12189205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Thioredoxin, a putative oncogene product, is overexpressed in gastric carcinoma and associated with increased proliferation and increased cell survival

1 reference

https://pubmed.ncbi.nlm.nih.gov/12189205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

A redox-inactive thioredoxin reduces growth and enhances apoptosis in WEHI7.2 cells

1 reference

https://pubmed.ncbi.nlm.nih.gov/12189205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Suberoylanilide hydroxamic acid, an inhibitor of histone deacetylase, suppresses the growth of prostate cancer cells in vitro and in vivo

1 reference

https://pubmed.ncbi.nlm.nih.gov/12189205

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1073/PNAS.182372299

1 reference

Europe PubMed Central

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:12189205 AND SRC:MED&resulttype=core&format=json

12 November 2019

2002PNAS...9911700B

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OpenCitations bibliographic resource ID

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Consolidated OpenCitations Corpus – April 2017

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Europe PubMed Central

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12 November 2019

PubMed publication ID

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12 November 2019

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