Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain (Q24534089)

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English	Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain	scientific article

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Functional analysis of genetic variation in catechol-O-methyltransferase (COMT): effects on mRNA, protein, and enzyme activity in postmortem human brain (English)

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genetic variation

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based on heuristic

inferred from title

Daniel R. Weinberger

13

object named as

Daniel R Weinberger

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author name string

Jingshan Chen

1

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Barbara K Lipska

2

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Nader Halim

3

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Quang D Ma

4

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Mitsuyuki Matsumoto

5

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Samer Melhem

6

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Bhaskar S Kolachana

7

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Thomas M Hyde

8

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Mary M Herman

9

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Jose Apud

10

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Michael F Egan

11

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Joel E Kleinman

12

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publication date

November 2004

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American Journal of Human Genetics

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75

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5

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807-21

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Catechol-O-methyltransferase-deficient mice exhibit sexually dimorphic changes in catecholamine levels and behavior

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Kinetic stabilization of Bacillus licheniformis alpha-amylase through introduction of hydrophobic residues at the surface

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Crystal structure of catechol O-methyltransferase

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Catechol-o-methyltransferase inhibition improves set-shifting performance and elevates stimulated dopamine release in the rat prefrontal cortex

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Schizophrenia genes, gene expression, and neuropathology: on the matter of their convergence

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7 April 2017

Effect of COMT Val108/158 Met genotype on frontal lobe function and risk for schizophrenia

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7 April 2017

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COMT haplotypes suggest P2 promoter region relevance for schizophrenia.

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Enzymatic O-methylation of epinephrine and other catechols.

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Catechol O -methyltransferase val 158 -met genotype and individual variation in the brain response to amphetamine

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A highly significant association between a COMT haplotype and schizophrenia.

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Methylation pharmacogenetics: catechol O-methyltransferase, thiopurine methyltransferase, and histamine N-methyltransferase

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Kinetics of human soluble and membrane-bound catechol O-methyltransferase: a revised mechanism and description of the thermolabile variant of the enzyme

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Cloning, expression and structure of catechol-O-methyltransferase.

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Genetics of red cell COMT activity: Analysis of thermal stability and family data

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Inheritance of low erythrocyte catechol-o-methyltransferase activity in man

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Human liver catechol-O-methyltransferase pharmacogenetics

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Brain catecholamine metabolism in catechol-O-methyltransferase (COMT)-deficient mice

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30 May 2018

Evoked extracellular dopamine in vivo in the medial prefrontal cortex.

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30 May 2018

Human catechol O-methyltransferase genetic variation: gene resequencing and functional characterization of variant allozymes

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Catechol O-methyltransferase Val158Met polymorphism in schizophrenia: differential effects of Val and Met alleles on cognitive stability and flexibility.

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Catechol-o-methyltransferase (COMT) and proline dehydrogenase (PRODH) mRNAs in the dorsolateral prefrontal cortex in schizophrenia, bipolar disorder, and major depression.

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29 November 2018

Expression analysis of neuregulin-1 in the dorsolateral prefrontal cortex in schizophrenia

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Presynaptic proteins in the prefrontal cortex of patients with schizophrenia and rats with abnormal prefrontal development

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A haplotype implicated in schizophrenia susceptibility is associated with reduced COMT expression in human brain

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Population variation in linkage disequilibrium across the COMT gene considering promoter region and coding region variation

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Dopamine axon varicosities in the prelimbic division of the rat prefrontal cortex exhibit sparse immunoreactivity for the dopamine transporter.

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Thermal stability and the biochemical genetics of erythrocyte catechol-O-methyl-transferase and plasma dopamine-beta-hydroxylase.

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Catechol-O-methyltransferase: thermolabile enzyme in erythrocytes of subjects homozygous for allele for low activity

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Catechol-O-methyltransferase biochemical genetics: Human lymphocyte enzyme

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12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Site-directed mutagenesis using a PCR-based staggered re-annealing method without restriction enzymes

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https://pubmed.ncbi.nlm.nih.gov/15457404

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Meta-analysis of whole-genome linkage scans of bipolar disorder and schizophrenia

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Consolidated OpenCitations Corpus – April 2017

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