Endoproteolytic processing of integrin pro-alpha subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7 (Q24531949)

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English	Endoproteolytic processing of integrin pro-alpha subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7	scientific article

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scholarly article

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Endoproteolytic processing of integrin pro-alpha subunits involves the redundant function of furin and proprotein convertase (PC) 5A, but not paired basic amino acid converting enzyme (PACE) 4, PC5B or PC7 (English)

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author name string

J C Lissitzky

1

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J Luis

2

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J S Munzer

3

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S Benjannet

4

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F Parat

5

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M Chrétien

6

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J Marvaldi

7

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N G Seidah

8

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language of work or name

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publication date

15 February 2000

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Biochemical Journal

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346 Pt 1

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133-8

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The prosegments of furin and PC7 as potent inhibitors of proprotein convertases. In vitro and ex vivo assessment of their efficacy and selectivity

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The Notch1 receptor is cleaved constitutively by a furin-like convertase

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Biosynthesis, Distinct Post-translational Modifications, and Functional Characterization of Lymphoma Proprotein Convertase

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The isoforms of proprotein convertase PC5 are sorted to different subcellular compartments

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Bioactivation of Müllerian inhibiting substance during gonadal development by a kex2/subtilisin-like endoprotease

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Comparative cellular processing of the human immunodeficiency virus (HIV-1) envelope glycoprotein gp160 by the mammalian subtilisin/kexin-like convertases

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Cellular processing of the nerve growth factor precursor by the mammalian pro-protein convertases

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Two independent targeting signals in the cytoplasmic domain determine trans-Golgi network localization and endosomal trafficking of the proprotein convertase furin

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Intracellular trafficking and activation of the furin proprotein convertase: localization to the TGN and recycling from the cell surface

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Integrins: versatility, modulation, and signaling in cell adhesion

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Comparative functional role of PC7 and furin in the processing of the HIV envelope glycoprotein gp160

1 reference

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Increased proteolytic processing of protein tyrosine phosphatase mu in confluent vascular endothelial cells: the role of PC5, a member of the subtilisin family

1 reference

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24 March 2017

The family of subtilisin/kexin like pro-protein and pro-hormone convertases: divergent or shared functions

1 reference

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Integrins: a family of cell surface receptors

1 reference

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Characterization of structural determinants and molecular mechanisms involved in pro-stromelysin-3 activation by 4-aminophenylmercuric acetate and furin-type convertases

1 reference

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Requirement of vascular integrin alpha v beta 3 for angiogenesis

1 reference

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The RGD motif and the C-terminal segment of proprotein convertase 1 are critical for its cellular trafficking but not for its intracellular binding to integrin alpha5beta1.

1 reference

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Proprotein cleavage of E-cadherin by furin in baculovirus over-expression system: potential role of other convertases in mammalian cells

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1 reference

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1 reference

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Deficient processing and activity of type I insulin-like growth factor receptor in the furin-deficient LoVo-C5 cells

1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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1 reference

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Lack of integrin alpha-chain endoproteolytic cleavage in furin-deficient human colon adenocarcinoma cells LoVo

1 reference

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27 September 2017

A second mutant allele of furin in the processing-incompetent cell line, LoVo. Evidence for involvement of the homo B domain in autocatalytic activation.

1 reference

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Localization of furin to the trans-Golgi network and recycling from the cell surface involves Ser and Tyr residues within the cytoplasmic domain.

1 reference

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1 reference

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Furin and proprotein convertase 7 (PC7)/lymphoma PC endogenously expressed in rat liver can be resolved into distinct post-Golgi compartments

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220832

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1 reference

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1 reference

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30 May 2018

Eukaryotic protein processing: endoproteolysis of precursor proteins

1 reference

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30 May 2018

Inhibition of intracellular proteolytic processing of soluble proproteins by an engineered α2-macroglobulin containing a furin recognition sequence in the bait region

1 reference

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30 May 2018

In vitro characterization of the novel proprotein convertase PC7.

1 reference

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30 May 2018

Proprotein conversion is determined by a multiplicity of factors including convertase processing, substrate specificity, and intracellular environment. Cell type-specific processing of human prorenin by the convertase PC1.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220832

30 May 2018

Evidence for furin-type activity-mediated C-terminal processing of profibrillin-1 and interference in the processing by certain mutations.

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220832

29 November 2018

Precursor convertases: an evolutionary ancient, cell-specific, combinatorial mechanism yielding diverse bioactive peptides and proteins

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220832

29 November 2018

Inhibition of HIV-1 gp160-dependent membrane fusion by a furin-directed alpha 1-antitrypsin variant

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1220832

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Proteolytic processing of the hepatocyte growth factor/scatter factor receptor by furin

1 reference

https://pubmed.ncbi.nlm.nih.gov/10657249

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/10657249

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based on heuristic

inferred from PubMed ID database lookup

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1 reference

https://pubmed.ncbi.nlm.nih.gov/10657249

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based on heuristic

inferred from PubMed ID database lookup

α v β 3 Integrin Expression in Normal and Atherosclerotic Artery

1 reference

https://pubmed.ncbi.nlm.nih.gov/10657249

12 December 2020

based on heuristic

inferred from PubMed ID database lookup

Identifiers

10.1042/BJ3460133

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release_4733iyk62vcqzj6jivs4a4whhe

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