Crystal structure of 5-aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans. (Q24531335)

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6 January 2020

title

Crystal structure of 5-aminolevulinate synthase, the first enzyme of heme biosynthesis, and its link to XLSA in humans (English)

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6 January 2020

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6 January 2020

Wolf-Dieter Schubert

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author name string

Isabel Astner

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6 January 2020

Jörg O Schulze

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6 January 2020

Joop van den Heuvel

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Dirk W Heinz

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language of work or name

English

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publication date

25 August 2005

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6 January 2020

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volume

24

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issue

18

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6 January 2020

page(s)

3166-3177

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Interaction between succinyl CoA synthetase and the heme-biosynthetic enzyme ALAS-E is disrupted in sideroblastic anemia

6 January 2020

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The solution structure and heme binding of the presequence of murine 5-aminolevulinate synthase

24 March 2017

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Solvent content of protein crystals

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24 March 2017

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Disorders of iron metabolism

24 March 2017

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24 March 2017

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22 April 2017

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5-Aminolevulinic acid synthase: mechanism, mutations and medicine

27 September 2017

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Aberrant iron accumulation and oxidized status of erythroid-specific delta-aminolevulinate synthase (ALAS2)-deficient definitive erythroblasts

27 September 2017

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Transient state kinetic investigation of 5-aminolevulinate synthase reaction mechanism

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Heme biosynthesis in mammalian systems: evidence of a Schiff base linkage between the pyridoxal 5'-phosphate cofactor and a lysine residue in 5-aminolevulinate synthase

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21 January 2018

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21 January 2018

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Pre-steady-state reaction of 5-aminolevulinate synthase. Evidence for a rate-determining product release

29 November 2018

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12 December 2020

Characterization of the rhodobacter sphaeroides 5-aminolaevulinic acid synthase isoenzymes, HemA and HemT, isolated from recombinant Escherichia coli

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12 December 2020

Lysine-313 of 5-Aminolevulinate Synthase Acts as a General Base during Formation of the Quinonoid Reaction Intermediates

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12 December 2020

Enzymatic synthesis of sigma-aminolevulinic acid

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12 December 2020

A continuous spectrophotometric assay for 5-aminolevulinate synthase that utilizes substrate cycling

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12 December 2020

Homology of 1-aminocyclopropane-1-carboxylate synthase, 8-amino-7-oxononanoate synthase, 2-amino-6-caprolactam racemase, 2,2-dialkylglycine decarboxylase, glutamate-1-semialdehyde 2,1-aminomutase and isopenicillin-N-epimerase with aminotransferases

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12 December 2020

Mutations at a glycine loop in aminolevulinate synthase affect pyridoxal phosphate cofactor binding and catalysis

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12 December 2020

Role of Arginine 439 in Substrate Binding of 5-Aminolevulinate Synthase

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12 December 2020

Identifiers

DOI

10.1038/SJ.EMBOJ.7600792

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:16121195 AND SRC:MED&resulttype=core&format=json

6 January 2020

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6 January 2020

PubMed publication ID

16121195

1 reference