Single-gene disorders: what role could moonlighting enzymes play? (Q24530918)

4 July 2017

1 reference

title

Single-gene disorders: what role could moonlighting enzymes play? (English)

1 reference

4 July 2017

Ganesh Sriram

1

1 reference

4 July 2017

Julian A Martinez

2

1 reference

4 July 2017

Edward R B McCabe

3

1 reference

4 July 2017

James C Liao

4

1 reference

4 July 2017

Katrina M Dipple

5

1 reference

4 July 2017

language of work or name

English

0 references

publication date

22 April 2005

1 reference

American Journal of Human Genetics

4 July 2017

published in

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4 July 2017

volume

76

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4 July 2017

issue

6

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4 July 2017

page(s)

911-924

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Association of late-onset Alzheimer's disease with genetic variation in multiple members of the GAPD gene family

4 July 2017

cites work

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24 March 2017

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24 March 2017

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24 March 2017

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24 March 2017

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Structure of the proline dehydrogenase domain of the multifunctional PutA flavoprotein

24 March 2017

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24 March 2017

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24 March 2017

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24 March 2017

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Induction of iron regulatory protein 1 RNA-binding activity by nitric oxide is associated with a concomitant increase in the labile iron pool: implications for DNA damage

24 March 2017

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24 March 2017

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24 March 2017

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Gene mutations in the succinate dehydrogenase subunit SDHB cause susceptibility to familial pheochromocytoma and to familial paraganglioma

24 March 2017

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24 March 2017

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Phosphoglycerate kinase acts in tumour angiogenesis as a disulphide reductase

24 March 2017

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Gene sharing in lens and cornea: facts and implications

24 March 2017

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Nucleoside diphosphate kinase from Pseudomonas aeruginosa: characterization of the gene and its role in cellular growth and exopolysaccharide alginate synthesis

24 March 2017

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Both the establishment and the maintenance of neuronal polarity require active mechanisms: critical roles of GSK-3beta and its upstream regulators

24 March 2017

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Glyceraldehyde 3-phosphate dehydrogenase-S, a sperm-specific glycolytic enzyme, is required for sperm motility and male fertility

24 March 2017

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The housekeeping gene xanthine oxidoreductase is necessary for milk fat droplet enveloping and secretion: gene sharing in the lactating mammary gland

24 March 2017

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Isolation, mapping, and functional expression of the mouse X chromosome glycerol kinase gene

24 March 2017

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Plasminogen binds specifically to alpha-enolase on rat neuronal plasma membrane

24 March 2017

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Properties of an adenosine triphosphate-stimulated factor that enhances the nuclear binding of activated glucocorticoid-receptor complex: binding to histone-agarose

24 March 2017

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Tau-crystallin/alpha-enolase: one gene encodes both an enzyme and a lens structural protein

24 March 2017

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Glyceraldehyde-3-phosphate dehydrogenase, apoptosis, and neurodegenerative diseases

24 March 2017

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Proteomic analysis of neurofibrillary tangles in Alzheimer disease identifies GAPDH as a detergent-insoluble paired helical filament tau binding protein

27 September 2017

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The double life of the Ku protein: facing the DNA breaks and the extracellular environment.

27 September 2017

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GSK-3beta regulates phosphorylation of CRMP-2 and neuronal polarity.

27 September 2017

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Identification of alpha-enolase as a nuclear DNA-binding protein in the zona fasciculata but not the zona reticularis of the human adrenal cortex

27 September 2017

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Differential regulation of phosphoglucose isomerase/autocrine motility factor activities by protein kinase CK2 phosphorylation.

27 September 2017

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IRP1 Ser-711 is a phosphorylation site, critical for regulation of RNA-binding and aconitase activities.

27 September 2017

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Phosphatidylinositol 3-kinase-mediated effects of glucose on vacuolar H -ATPase assembly, translocation, and acidification of intracellular compartments in renal epithelial cells.

27 September 2017

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Mass spectrometry and the search for moonlighting proteins.

27 September 2017

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Molecular mechanisms for multitasking: recent crystal structures of moonlighting proteins.

27 September 2017

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Regulation of milk lipid formation and secretion in the mouse mammary gland.

27 September 2017

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Influence of diadenosine tetraphosphate (Ap4A) on lipid metabolism

27 September 2017

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Physiological roles of xanthine oxidoreductase

27 September 2017

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Expression of butyrophilin (Btn1a1) in lactating mammary gland is essential for the regulated secretion of milk-lipid droplets

27 September 2017

1 reference

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Glycogen synthase kinase 3: a drug target for CNS therapies

27 September 2017

1 reference

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DNA repair-deficient diseases, xeroderma pigmentosum, Cockayne syndrome and trichothiodystrophy

27 September 2017

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Transcriptome-based determination of multiple transcription regulator activities in Escherichia coli by using network component analysis

27 September 2017

1 reference

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Network component analysis: reconstruction of regulatory signals in biological systems

27 September 2017

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Proteome Analysis of Lens Epithelia, Fibers, and the HLE B-3 Cell Line

27 September 2017

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DAX1 and its network partners: exploring complexity in development

27 September 2017

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How versatile are inositol phosphate kinases?

27 September 2017

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Moonlighting proteins: old proteins learning new tricks.

27 September 2017

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Crystallin genes: specialization by changes in gene regulation may precede gene duplication

27 September 2017

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Gelsolin and plasminogen activator inhibitor-1 are Ap3A-binding proteins

27 September 2017

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Pyruvate kinase: current status of regulatory and functional properties

27 September 2017

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Multifunctional proteins: examples of gene sharing

27 September 2017

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The multifunctional or moonlighting protein CD26/DPPIV.

27 September 2017

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27 September 2017

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Germline mutations in FH predispose to dominantly inherited uterine fibroids, skin leiomyomata and papillary renal cell cancer

27 September 2017

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27 September 2017

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Glycerol kinase deficiency: evidence for complexity in a single gene disorder

27 September 2017

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Glyceraldehyde-3-phosphate dehydrogenase in neurodegeneration and apoptosis signaling.

27 September 2017

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Glyceraldehyde-3-phosphate dehydrogenase is required for vesicular transport in the early secretory pathway

27 September 2017

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Isolated and contiguous glycerol kinase gene disorders: a review

27 September 2017

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Modifier genes convert "simple" Mendelian disorders to complex traits

27 September 2017

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Five cases of isolated glycerol kinase deficiency, including two families: failure to find genotype:phenotype correlation

27 September 2017

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Glyceraldehyde-3-phosphate dehydrogenase and apoptosis

27 September 2017

1 reference

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New insights into an old protein: the functional diversity of mammalian glyceraldehyde-3-phosphate dehydrogenase.

27 September 2017

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Monogenic traits are not simple: lessons from phenylketonuria

27 September 2017

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27 September 2017

Moonlighting proteins.

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Molecular basis of neurological dysfunction coupled with haemolytic anaemia in human glucose-6-phosphate isomerase (GPI) deficiency

27 September 2017

1 reference

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Xanthine oxidoreductase in human mammary epithelial cells: activation in response to inflammatory cytokines

27 September 2017

1 reference

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Glyceraldehyde-3-phosphate dehydrogenase: Nuclear translocation participates in neuronal and nonneuronal cell death

27 September 2017

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Tumor cell autocrine motility factor is the neuroleukin/phosphohexose isomerase polypeptide

27 September 2017

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Multifunctional proteins in Tetrahymena: 14-nm filament protein/citrate synthase and translation elongation factor-1 alpha.

27 September 2017

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Molecular cloning of rat liver glucocorticoid-receptor translocation promoter

27 September 2017

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The iron-responsive element-binding protein: localization of the RNA-binding site to the aconitase active-site cleft

27 September 2017

1 reference

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A mutation in glyceraldehyde 3-phosphate dehydrogenase alters endocytosis in CHO cells

27 September 2017

1 reference

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Yeast mitochondrial NAD( )-dependent isocitrate dehydrogenase is an RNA-binding protein

27 September 2017

1 reference

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A porcine brain protein (35 K protein) which bundles microtubules and its identification as glyceraldehyde 3-phosphate dehydrogenase

27 September 2017

1 reference

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Pore protein and the hexokinase-binding protein from the outer membrane of rat liver mitochondria are identical

27 September 2017

1 reference

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Molecular cloning and expression of neuroleukin, a neurotrophic factor for spinal and sensory neurons

27 September 2017

1 reference

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Mouse glucose-6-phosphate isomerase and neuroleukin have identical 3' sequences

27 September 2017

1 reference

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The neurotrophic factor neuroleukin is 90% homologous with phosphohexose isomerase.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Tetrahymena 14-nm filament-forming protein has citrate synthase activity

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

A human nuclear uracil DNA glycosylase is the 37-kDa subunit of glyceraldehyde-3-phosphate dehydrogenase

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Deficiency of skeletal muscle succinate dehydrogenase and aconitase. Pathophysiology of exercise in a novel human muscle oxidative defect

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

An iron-sulfur cluster plays a novel regulatory role in the iron-responsive element binding protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Purification and characterization of cytosolic aconitase from beef liver and its relationship to the iron-responsive element binding protein

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Disclosure of a pro-apoptotic glyceraldehyde-3-phosphate dehydrogenase promoter: anti-dementia drugs depress its activation in apoptosis

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Species specificity of the cytokine function of phosphoglucose isomerase

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Phenotypes of patients with "simple" Mendelian disorders are complex traits: thresholds, modifiers, and systems dynamics

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

ONO-1603, a potential antidementia drug, shows neuroprotective effects and increases m3-muscarinic receptor mRNA levels in differentiating rat cerebellar granule neurons

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

The binding of glycerol kinase to the outer membrane of rat liver mitochondria: Its importance in metabolic regulation

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Human glycerol kinase deficiency: An inborn error of compartmental metabolism

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Pyruvate kinase of Escherichia coli. Its role in supplying nucleoside triphosphates in cells under anaerobic conditions.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

An in vitro novel mechanism of regulating the activity of pyruvate kinase M2 by thyroid hormone and fructose 1,6-bisphosphate

30 May 2018

1 reference

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Role of cell-surface lysines in plasminogen binding to cells: identification of .alpha.-enolase as a candidate plasminogen receptor

30 May 2018

1 reference

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Pro-apoptotic protein glyceraldehyde-3-phosphate dehydrogenase promotes the formation of Lewy body-like inclusions

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Glyceraldehyde-3-phosphate dehydrogenase and actin associate with RNA polymerase II and interact with its Rpb7 subunit.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Functional domains of Brevibacillus thermoruber lon protease for oligomerization and DNA binding: role of N-terminal and sensor and substrate discrimination domains.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

The glycolytic enzyme aldolase mediates assembly, expression, and activity of vacuolar H -ATPase

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Diadenosine tetraphosphate protects against injuries induced by ischemia and 6-hydroxydopamine in rat brain.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Do current sequence analysis algorithms disclose multifunctional (moonlighting) proteins?

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Inhibition of weak-base amine-induced lysis of lysosomes by cytosol

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Plasmin reduction by phosphoglycerate kinase is a thiol-independent process

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Mouse mammary gland xanthine oxidoreductase: purification, characterization, and regulation.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

ONO-1603, a potential antidementia drug, delays age-induced apoptosis and suppresses overexpression of glyceraldehyde-3-phosphate dehydrogenase in cultured central nervous system neurons.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Glyceraldehyde-3-phosphate dehydrogenase and Nm23-H1/nucleoside diphosphate kinase A. Two old enzymes combine for the novel Nm23 protein phosphotransferase function

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Phosphorylation of the hepatitis B virus core protein by glyceraldehyde-3-phosphate dehydrogenase protein kinase activity

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Overexpression of glyceraldehyde-3-phosphate dehydrogenase is involved in low K -induced apoptosis but not necrosis of cultured cerebellar granule cells

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Glycerol kinase deficiency in two brothers with and without clinical manifestations.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=1196451

Binding of Aldolase and Triosephosphate Dehydrogenase to F-Actin and Modification of Catalytic Properties of Aldolase

29 November 2018

1 reference

12 December 2020

Evidence for identity between the hexokinase-binding protein and the mitochondrial porin in the outer membrane of rat liver mitochondria

1 reference

12 December 2020

Nuclear translocation of GAPDH-GFP fusion protein during apoptosis

1 reference

12 December 2020

A characterization of the activities of iron regulatory protein 1 in various farm animal species

1 reference

12 December 2020

1 reference

12 December 2020

An ATP-stimulated factor that enhances the nuclear binding of "activated" receptor-glucocorticoid complex

1 reference

12 December 2020

Glyceraldehyde-3-phosphate dehydrogenase is one of the three major RNA-binding proteins of rabbit reticulocytes

1 reference

12 December 2020

Autophosphorylation of glyceraldehydephosphate dehydrogenase and phosphorylation of protein from skeletal muscle microsomes

1 reference

12 December 2020

Transcriptional stimulation by thyroid hormone of a cytosolic thyroid hormone binding protein which is homologous to a subunit of pyruvate kinase M1

1 reference

12 December 2020

Sequence-specific binding of transfer RNA by glyceraldehyde-3-phosphate dehydrogenase

1 reference

12 December 2020

Isolation of a novel 45 kDa plasminogen receptor from human endothelial cells

1 reference

12 December 2020

Uracil DNA-glycosylase/glyceraldehyde-3-phosphate dehydrogenase is an Ap4A binding protein

1 reference

12 December 2020

Glyceraldehyde-3-phosphate dehydrogenase is over-expressed during apoptotic death of neuronal cultures and is recognized by a monoclonal antibody against amyloid plaques from Alzheimer's brain

1 reference

12 December 2020

The differentiation and maturation mediator for human myeloid leukemia cells shares homology with neuroleukin or phosphoglucose isomerase

1 reference

12 December 2020

Multifunctional lens crystallins and corneal enzymes. More than meets the eye

1 reference

12 December 2020

Identifiers

DOI

10.1086/430799

1 reference

OpenCitations bibliographic resource ID

4 July 2017

411354

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

4 July 2017

1 reference