NLR family member NLRC5 is a transcriptional regulator of MHC class I genes (Q24338949)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20639463 AND SRC:MED&resulttype=core&format=json

8 February 2020

title

NLR family member NLRC5 is a transcriptional regulator of MHC class I genes (English)

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Class II major histocompatibility complex transactivator

8 February 2020

main subject

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NLR family CARD domain containing 5

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positive regulation of interferon-gamma-mediated signaling pathway

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NLR family, CARD domain containing 5

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author

Peter J Van den Elsen

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8 February 2020

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Koichi S Kobayashi

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8 February 2020

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Torsten B Meissner

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8 February 2020

author name string

Amy Li

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8 February 2020

Amlan Biswas

3

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8 February 2020

Kyoung-Hee Lee

4

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8 February 2020

Yuen-Joyce Liu

5

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8 February 2020

Erkan Bayir

6

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8 February 2020

Dimitrios Iliopoulos

7

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8 February 2020

language of work or name

English

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publication date

16 July 2010

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Proceedings of the National Academy of Sciences of the United States of America

8 February 2020

published in

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volume

107

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issue

31

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8 February 2020

page(s)

13794-13799

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NLRC5 negatively regulates the NF-kappaB and type I interferon signaling pathways

8 February 2020

cites work

1 reference

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The nucleotide-binding oligomerization domain-like receptor NLRC5 is involved in IFN-dependent antiviral immune responses

19 March 2017

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An epigenetic switch involving NF-kappaB, Lin28, Let-7 MicroRNA, and IL6 links inflammation to cell transformation

19 March 2017

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The bare lymphocyte syndrome: molecular clues to the transcriptional regulation of major histocompatibility complex class II genes

19 March 2017

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Complementation cloning of an MHC class II transactivator mutated in hereditary MHC class II deficiency (or bare lymphocyte syndrome)

19 March 2017

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Mini-review: Specificity and expression of CIITA, the master regulator of MHC class II genes

19 March 2017

1 reference

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Genetic control of MHC class II expression

19 March 2017

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The bare lymphocyte syndrome and the regulation of MHC expression

19 March 2017

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AAA proteins: have engine, will work

19 March 2017

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Nod2 is required for the regulation of commensal microbiota in the intestine

7 April 2017

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Regulation of MHC class I assembly and peptide binding

27 September 2017

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NLRs at the intersection of cell death and immunity

27 September 2017

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NLR proteins: integral members of innate immunity and mediators of inflammatory diseases

27 September 2017

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Classical nuclear localization signals: definition, function, and interaction with importin alpha

27 September 2017

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All the peptides that fit: the beginning, the middle, and the end of the MHC class I antigen-processing pathway

27 September 2017

1 reference

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Transcriptional regulation of the MHC class II antigen presentation pathway

27 September 2017

1 reference

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CIITA coordinates multiple histone acetylation modifications at the HLA-DRA promoter

27 September 2017

1 reference

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Is antigen presentation the primary function of HLA-G?

27 September 2017

1 reference

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Dendritic cell-specific MHC class II transactivator contains a caspase recruitment domain that confers potent transactivation activity

27 September 2017

1 reference

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Acetylation by PCAF enhances CIITA nuclear accumulation and transactivation of major histocompatibility complex class II genes

27 September 2017

1 reference

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CIITA is a transcriptional coactivator that is recruited to MHC class II promoters by multiple synergistic interactions with an enhanceosome complex

27 September 2017

1 reference

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Functions of nonclassical MHC and non-MHC-encoded class I molecules.

27 September 2017

1 reference

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Two distinct gamma interferon-inducible promoters of the major histocompatibility complex class II transactivator gene are differentially regulated by STAT1, interferon regulatory factor 1, and transforming growth factor beta

27 September 2017

1 reference

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CIITA stimulation of transcription factor binding to major histocompatibility complex class II and associated promoters in vivo

27 September 2017

1 reference

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Mechanisms of MHC class I--restricted antigen processing

27 September 2017

1 reference

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Induction of MHC class I expression by the MHC class II transactivator CIITA.

27 September 2017

1 reference

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Importance of acidic, proline/serine/threonine-rich, and GTP-binding regions in the major histocompatibility complex class II transactivator: generation of transdominant-negative mutants

27 September 2017

1 reference

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Class II-antigen-negative patient and mutant B-cell lines represent at least three, and probably four, distinct genetic defects defined by complementation analysis

27 September 2017

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Regulation of MHC class II expression by interferon-gamma mediated by the transactivator gene CIITA.

27 September 2017

1 reference

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Regulation of MHC class I and II gene transcription: differences and similarities

27 September 2017

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Shared regulatory elements in the promoters of MHC class I and class II genes

30 May 2018

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Identification of distinct regions of 5' flanking DNA that mediate constitutive, IFN-gamma, STAT1, and TGF-beta-regulated expression of the class II transactivator gene.

30 May 2018

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Class II transactivator (CIITA) is sufficient for the inducible expression of major histocompatibility complex class II genes.

30 May 2018

1 reference

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GTP-dependent recruitment of CIITA to the class II major histocompatibility complex promoter.

30 May 2018

1 reference

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Mechanisms of nuclear import and export that control the subcellular localization of class II transactivator

29 November 2018

1 reference

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Reduced IL-4-, lipopolysaccharide-, and IFN-gamma-induced MHC class II expression in mice lacking class II transactivator due to targeted deletion of the GTP-binding domain

29 November 2018

1 reference

12 December 2020

Mice lacking the MHC class II transactivator (CIITA) show tissue-specific impairment of MHC class II expression

1 reference

12 December 2020

Site alpha is crucial for two routes of IFN gamma-induced MHC class I transactivation: the ISRE-mediated route and a novel pathway involving CIITA

1 reference

12 December 2020

Activation of the MHC class II transactivator CIITA by interferon-gamma requires cooperative interaction between Stat1 and USF-1

1 reference

12 December 2020

Mice lacking the transcription factor CIITA--a second look

1 reference

12 December 2020

A defect in the nuclear translocation of CIITA causes a form of type II bare lymphocyte syndrome

1 reference

12 December 2020

Synergistic induction of HLA class I expression by RelA and CIITA

1 reference

12 December 2020

The MHC-specific enhanceosome and its role in MHC class I and beta(2)-microglobulin gene transactivation

1 reference

12 December 2020

Identifiers

DOI

10.1073/PNAS.1008684107

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20639463 AND SRC:MED&resulttype=core&format=json

8 February 2020

ADS bibcode

2010PNAS..10713794M

0 references

1 reference

2 references

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20639463 AND SRC:MED&resulttype=core&format=json

8 February 2020

PubMed publication ID

20639463

2 references