The ubiquitination of rag A GTPase by RNF152 negatively regulates mTORC1 activation (Q24337237)

mechanistic target of rapamycin kinase

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Ras related GTP binding A

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TSC complex subunit 2

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Ubiquitin conjugating enzyme E2 N

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negative regulation of TORC1 signaling

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Ring finger protein 152

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protein ubiquitination

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15

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author name string

Lu Deng

1

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10 June 2020

Cong Jiang

2

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10 June 2020

Lei Chen

3

1 reference

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Jiali Jin

4

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10 June 2020

Jie Wei

5

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10 June 2020

Linlin Zhao

6

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10 June 2020

Minghui Chen

7

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10 June 2020

Weijuan Pan

8

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Yan Xu

9

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Hongshang Chu

10

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10 June 2020

Xinbo Wang

11

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10 June 2020

Xin Ge

12

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Dali Li

13

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Lujian Liao

14

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10 June 2020

Li Li

16

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10 June 2020

Ping Wang

17

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10 June 2020

language of work or name

English

0 references

publication date

4 June 2015

0 references

published in

Molecular Cell

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volume

58

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issue

5

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page(s)

804-818

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RNF152, a novel lysosome localized E3 ligase with pro-apoptotic activities

10 June 2020

cites work

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

7 January 2021

Ragulator-Rag complex targets mTORC1 to the lysosomal surface and is necessary for its activation by amino acids

1 reference

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7 January 2021

Leucyl-tRNA synthetase is an intracellular leucine sensor for the mTORC1-signaling pathway

1 reference

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7 January 2021

mTOR signaling in growth control and disease

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

7 January 2021

Ragulator is a GEF for the rag GTPases that signal amino acid levels to mTORC1

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

7 January 2021

Regulation of TORC1 in response to amino acid starvation via lysosomal recruitment of TSC2.

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

7 January 2021

Sestrins function as guanine nucleotide dissociation inhibitors for Rag GTPases to control mTORC1 signaling

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

7 January 2021

The Sestrins interact with GATOR2 to negatively regulate the amino-acid-sensing pathway upstream of mTORC1

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

7 January 2021

Sestrins inhibit mTORC1 kinase activation through the GATOR complex

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

7 January 2021

Ubiquitin code assembly and disassembly

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

7 January 2021

K63 polyubiquitination and activation of mTOR by the p62-TRAF6 complex in nutrient-activated cells

1 reference

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7 January 2021

The folliculin tumor suppressor is a GAP for the RagC/D GTPases that signal amino acid levels to mTORC1.

1 reference

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7 January 2021

Amino acids and mTORC1: from lysosomes to disease

1 reference

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7 January 2021

mTOR couples cellular nutrient sensing to organismal metabolic homeostasis

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

7 January 2021

mTOR interacts with raptor to form a nutrient-sensitive complex that signals to the cell growth machinery

1 reference

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7 January 2021

Insulin activation of Rheb, a mediator of mTOR/S6K/4E-BP signaling, is inhibited by TSC1 and 2

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

7 January 2021

Themes and variations on ubiquitylation

1 reference

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7 January 2021

The novel lipid raft adaptor p18 controls endosome dynamics by anchoring the MEK-ERK pathway to late endosomes.

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

7 January 2021

A lysosome-to-nucleus signalling mechanism senses and regulates the lysosome via mTOR and TFEB

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

7 January 2021

Regulation of TORC1 by Rag GTPases in nutrient response

1 reference

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7 January 2021

AMPK and mTOR regulate autophagy through direct phosphorylation of Ulk1

1 reference

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7 January 2021

Atypical ubiquitylation - the unexplored world of polyubiquitin beyond Lys48 and Lys63 linkages.

1 reference

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7 January 2021

Amino acid signalling upstream of mTOR

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

1 reference

7 January 2021

Nutrients and growth factors in mTORC1 activation.

1 reference

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7 January 2021

Cloning of a novel family of mammalian GTP-binding proteins (RagA, RagBs, RagB1) with remote similarity to the Ras-related GTPases

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

7 January 2021

Novel G proteins, Rag C and Rag D, interact with GTP-binding proteins, Rag A and Rag B

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

7 January 2021

Certain pairs of ubiquitin-conjugating enzymes (E2s) and ubiquitin-protein ligases (E3s) synthesize nondegradable forked ubiquitin chains containing all possible isopeptide linkages.

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

7 January 2021

Rag GTPases mediate amino acid-dependent recruitment of TFEB and MITF to lysosomes

1 reference

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7 January 2021

Mammalian cell size is controlled by mTOR and its downstream targets S6K1 and 4EBP1/eIF4E

1 reference

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7 January 2021

The Rag GTPases bind raptor and mediate amino acid signaling to mTORC1

1 reference

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7 January 2021

A Tumor suppressor complex with GAP activity for the Rag GTPases that signal amino acid sufficiency to mTORC1

1 reference

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7 January 2021

Ubiquitin-binding proteins: decoders of ubiquitin-mediated cellular functions

1 reference

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7 January 2021

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

1 reference

7 January 2021

RING domain E3 ubiquitin ligases

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

7 January 2021

MTORC1 functions as a transcriptional regulator of autophagy by preventing nuclear transport of TFEB.

1 reference

https://api.crossref.org/works/10.1016/J.MOLCEL.2015.03.033

7 January 2021

10.1016/J.MOLCEL.2015.03.033

Identifiers

DOI

2 references

Consolidated OpenCitations Corpus – April 2017

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:25936802 AND SRC:MED&resulttype=core&format=json

10 June 2020

1 reference

Consolidated OpenCitations Corpus – April 2017

2 references

Consolidated OpenCitations Corpus – April 2017