Novel mechanisms of fibroblast growth factor receptor 1 regulation by extracellular matrix protein anosmin-1 (Q24336798)

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19696444 AND SRC:MED&resulttype=core&format=json

5 February 2020

title

Novel mechanisms of fibroblast growth factor receptor 1 regulation by extracellular matrix protein anosmin-1 (English)

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5 February 2020

0 references

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fibroblast growth factor receptor 1

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identical protein binding

GOA release 2020-03-11

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GOA release 2020-03-11

author

Scott E Guimond

2

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5 February 2020

Soo-Hyun Kim

7

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5 February 2020

5

Erhard Hohenester

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5 February 2020

author name string

Youli Hu

1

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5 February 2020

Paul Travers

3

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5 February 2020

Steven Cadman

4

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5 February 2020

Jeremy E Turnbull

6

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5 February 2020

Pierre-Marc Bouloux

8

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5 February 2020

language of work or name

English

0 references

publication date

20 August 2009

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Journal of Biological Chemistry

5 February 2020

published in

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5 February 2020

volume

284

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5 February 2020

issue

43

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5 February 2020

page(s)

29905-29920

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Digenic mutations account for variable phenotypes in idiopathic hypogonadotropic hypogonadism

5 February 2020

cites work

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Cellular signaling by fibroblast growth factor receptors

19 March 2017

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Insights into the molecular basis for fibroblast growth factor receptor autoinhibition and ligand-binding promiscuity

19 March 2017

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Crystal structure of fibroblast growth factor receptor ectodomain bound to ligand and heparin

19 March 2017

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Crystal structure of a ternary FGF-FGFR-heparin complex reveals a dual role for heparin in FGFR binding and dimerization

19 March 2017

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Crystal structures of two FGF-FGFR complexes reveal the determinants of ligand-receptor specificity

19 March 2017

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Structural basis for FGF receptor dimerization and activation

19 March 2017

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A gene deleted in Kallmann's syndrome shares homology with neural cell adhesion and axonal path-finding molecules

19 March 2017

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Structure of the Tandem Fibronectin Type 3 Domains of Neural Cell Adhesion Molecule

19 March 2017

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Structural basis for a direct interaction between FGFR1 and NCAM and evidence for a regulatory role of ATP

19 March 2017

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Fibronectin type III (FN3) modules of the neuronal cell adhesion molecule L1 interact directly with the fibroblast growth factor (FGF) receptor

19 March 2017

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The candidate gene for the X-linked Kallmann syndrome encodes a protein related to adhesion molecules

19 March 2017

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Identification of Sef, a novel modulator of FGF signalling

19 March 2017

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Molecular modelling and experimental studies of mutation and cell-adhesion sites in the fibronectin type III and whey acidic protein domains of human anosmin-1

19 March 2017

1 reference

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The neural cell adhesion molecule binds to fibroblast growth factor receptor 2

19 March 2017

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The complex genetics of Kallmann syndrome: KAL1, FGFR1, FGF8, PROKR2, PROK2, et al.

19 March 2017

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Fibroblast growth factor 8 signaling through fibroblast growth factor receptor 1 is required for the emergence of gonadotropin-releasing hormone neurons.

27 September 2017

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Evidence that heparin saccharides promote FGF2 mitogenesis through two distinct mechanisms

27 September 2017

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Diversity in fibroblast growth factor receptor 1 regulation: learning from the investigation of Kallmann syndrome.

27 September 2017

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Functional dissection of the Drosophila Kallmann's syndrome protein DmKal-1.

27 September 2017

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The fibroblast growth factor receptor acid box is essential for interactions with N-cadherin and all of the major isoforms of neural cell adhesion molecule

27 September 2017

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Mutations in fibroblast growth factor receptor 1 cause Kallmann syndrome with a wide spectrum of reproductive phenotypes

27 September 2017

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A protein canyon in the FGF-FGF receptor dimer selects from an à la carte menu of heparan sulfate motifs

27 September 2017

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FGF signaling in the developing endochondral skeleton

27 September 2017

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Structural basis for fibroblast growth factor receptor activation

27 September 2017

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The product of X-linked Kallmann's syndrome gene (KAL1) affects the migratory activity of gonadotropin-releasing hormone (GnRH)-producing neurons.

27 September 2017

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Targeted expression of a dominant-negative fibroblast growth factor (FGF) receptor in gonadotropin-releasing hormone (GnRH) neurons reduces FGF responsiveness and the size of GnRH neuronal population

27 September 2017

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Cross-talk of anosmin-1, the protein implicated in X-linked Kallmann's syndrome, with heparan sulphate and urokinase-type plasminogen activator.

27 September 2017

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27 September 2017

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Conditional activation of fibroblast growth factor receptor (FGFR) 1, but not FGFR2, in prostate cancer cells leads to increased osteopontin induction, extracellular signal-regulated kinase activation, and in vivo proliferation

27 September 2017

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Biological activities of fibroblast growth factor-2 in the adult myocardium

27 September 2017

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27 September 2017

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27 September 2017

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CAMs and axonal growth: a critical evaluation of the role of calcium and the MAPK cascade

27 September 2017

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Fibroblast growth factor receptor signalling is dictated by specific heparan sulphate saccharides

27 September 2017

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Expression cDNA Cloning of the KGF Receptor by Creation of a Transforming Autocrine Loop

27 September 2017

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Src kinase modulates the activation, transport and signalling dynamics of fibroblast growth factor receptors

27 September 2017

1 reference

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Expression of a dominant negative FGF receptor inhibits axonal growth and FGF receptor phosphorylation stimulated by CAMs

30 May 2018

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Neuroblast long-term cell cultures from human fetal olfactory epithelium respond to odors.

30 May 2018

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Anosmin-1 modulates the FGF-2-dependent migration of oligodendrocyte precursors in the developing optic nerve.

30 May 2018

1 reference

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Extended and flexible domain solution structure of the extracellular matrix protein anosmin-1 by X-ray scattering, analytical ultracentrifugation and constrained modelling.

29 November 2018

1 reference

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Anosmin-1 modulates fibroblast growth factor receptor 1 signaling in human gonadotropin-releasing hormone olfactory neuroblasts through a heparan sulfate-dependent mechanism.

29 November 2018

1 reference

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Towards a resolution of the stoichiometry of the fibroblast growth factor (FGF)-FGF receptor-heparin complex

29 November 2018

1 reference

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Developmental regulation of gonadotropin-releasing hormone neurons by fibroblast growth factor signaling

29 November 2018

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The transmembrane protein XFLRT3 forms a complex with FGF receptors and promotes FGF signalling

29 November 2018

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Loss-of-function mutations in FGFR1 cause autosomal dominant Kallmann syndrome

29 November 2018

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An essential heparin-binding domain in the fibroblast growth factor receptor kinase

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19696444

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Antiangiogenic antithrombin blocks the heparan sulfate-dependent binding of proangiogenic growth factors to their endothelial cell receptors: evidence for differential binding of antiangiogenic and anticoagulant forms of antithrombin to proangiogeni

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/19696444

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1074/JBC.M109.049155

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19696444 AND SRC:MED&resulttype=core&format=json

5 February 2020

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:19696444 AND SRC:MED&resulttype=core&format=json

5 February 2020

PubMed publication ID

19696444

1 reference