Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1 (Q24336739)

21 June 2017

title

Identification of novel Smad2 and Smad3 associated proteins in response to TGF-beta1 (English)

1 reference

identical protein binding

21 June 2017

0 references

1 reference

GOA release 2020-03-11

1 reference

GOA release 2020-03-11

author

Jennifer A. Pietenpol

8

object named as

Jennifer A Pietenpol

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21 June 2017

9

Harold L Moses

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21 June 2017

Kimberly A Brown

1

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21 June 2017

Amy-Joan L Ham

2

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21 June 2017

Cara N Clark

3

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21 June 2017

Nahum Meller

4

1 reference

21 June 2017

Brian K Law

5

1 reference

21 June 2017

Anna Chytil

6

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21 June 2017

Nikki Cheng

7

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21 June 2017

language of work or name

English

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publication date

1 October 2008

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Journal of Cellular Biochemistry

21 June 2017

published in

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21 June 2017

volume

105

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21 June 2017

issue

2

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21 June 2017

page(s)

596-611

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The integral inner nuclear membrane protein MAN1 physically interacts with the R-Smad proteins to repress signaling by the transforming growth factor-{beta} superfamily of cytokines

21 June 2017

cites work

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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Heteromeric and homomeric interactions correlate with signaling activity and functional cooperativity of Smad3 and Smad4/DPC4

19 March 2017

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MADR2 is a substrate of the TGFbeta receptor and its phosphorylation is required for nuclear accumulation and signaling

19 March 2017

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19 March 2017

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MADR2 maps to 18q21 and encodes a TGFbeta-regulated MAD-related protein that is functionally mutated in colorectal carcinoma

19 March 2017

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Inactivation of the type II TGF-beta receptor in colon cancer cells with microsatellite instability

19 March 2017

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19 March 2017

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19 March 2017

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Proteomics-based identification of proteins interacting with Smad3: SREBP-2 forms a complex with Smad3 and inhibits its transcriptional activity

19 March 2017

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Loss-of-function mutations in LEMD3 result in osteopoikilosis, Buschke-Ollendorff syndrome and melorheostosis

19 March 2017

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Identification of three novel Smad binding proteins involved in cell polarity

19 March 2017

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E2F4/5 and p107 as Smad cofactors linking the TGFbeta receptor to c-myc repression

19 March 2017

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TGF-beta induces assembly of a Smad2-Smurf2 ubiquitin ligase complex that targets SnoN for degradation

19 March 2017

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Role of transforming growth factor-beta signaling in cancer

19 March 2017

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c-Ski acts as a transcriptional co-repressor in transforming growth factor-beta signaling through interaction with smads

19 March 2017

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Mice lacking Smad3 show accelerated wound healing and an impaired local inflammatory response

19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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19 March 2017

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Phosphorylation of Ser465 and Ser467 in the C Terminus of Smad2 Mediates Interaction with Smad4 and Is Required for Transforming Growth Factor-β Signaling

19 March 2017

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Normal keratinization in a spontaneously immortalized aneuploid human keratinocyte cell line

19 March 2017

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How cells read TGF-beta signals

7 April 2017

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Transcriptional control by the TGF-beta/Smad signaling system

7 April 2017

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Direct binding of Smad3 and Smad4 to critical TGF beta-inducible elements in the promoter of human plasminogen activator inhibitor-type 1 gene

7 April 2017

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Femtomole sequencing of proteins from polyacrylamide gels by nano-electrospray mass spectrometry

7 April 2017

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DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1

7 April 2017

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Method to correlate tandem mass spectra of modified peptides to amino acid sequences in the protein database

7 April 2017

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A tale of two proteins: differential roles and regulation of Smad2 and Smad3 in TGF-beta signaling

10 May 2017

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Endogenous transforming growth factor-beta receptor-mediated Smad signaling complexes analyzed by mass spectrometry

27 September 2017

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RING finger-dependent ubiquitination by PRAJA is dependent on TGF-beta and potentially defines the functional status of the tumor suppressor ELF.

27 September 2017

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27 September 2017

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The endogenous ratio of Smad2 and Smad3 influences the cytostatic function of Smad3.

27 September 2017

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The deubiquitinating enzyme UCH37 interacts with Smads and regulates TGF-beta signalling

27 September 2017

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MAN1, an integral protein of the inner nuclear membrane, binds Smad2 and Smad3 and antagonizes transforming growth factor-beta signaling.

27 September 2017

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The novel Cdc42 guanine nucleotide exchange factor, zizimin1, dimerizes via the Cdc42-binding CZH2 domain

27 September 2017

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Casein kinase Iepsilon plays a functional role in the transforming growth factor-beta signaling pathway

27 September 2017

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Smad7 is required for TGF-beta-induced activation of the small GTPase Cdc42.

27 September 2017

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27 September 2017

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27 September 2017

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Nuclear factor YY1 inhibits transforming growth factor beta- and bone morphogenetic protein-induced cell differentiation

27 September 2017

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Zizimin1, a novel Cdc42 activator, reveals a new GEF domain for Rho proteins

27 September 2017

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Regulation of cell proliferation by Smad proteins

27 September 2017

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Transforming growth factor-beta-induced mobilization of actin cytoskeleton requires signaling by small GTPases Cdc42 and RhoA

27 September 2017

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27 September 2017

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c-myc is a downstream target of the Smad pathway

27 September 2017

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TGFbeta influences Myc, Miz-1 and Smad to control the CDK inhibitor p15INK4b

27 September 2017

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Rho signals to cell growth and apoptosis

27 September 2017

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Inhibiting mutations in the transforming growth factor beta type 2 receptor in recurrent human breast cancer.

27 September 2017

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Smad2, Smad3 and Smad4 cooperate with Sp1 to induce p15(Ink4B) transcription in response to TGF-beta

27 September 2017

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Loss of Smad3 modulates wound healing

27 September 2017

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TGF-beta receptors and DNA repair genes, coupled targets in a pathway of human colon carcinogenesis

27 September 2017

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Transcriptional repression of the transforming growth factor-beta type I receptor gene by DNA methylation results in the development of TGF-beta resistance in human gastric cancer

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Induction of apoptosis by Smad3 and down-regulation of Smad3 expression in response to TGF-beta in human normal lung epithelial cells

27 September 2017

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27 September 2017

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Regulation of the human p21/WAF1/Cip1 promoter in hepatic cells by functional interactions between Sp1 and Smad family members

27 September 2017

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TβRI Phosphorylation of Smad2 on Ser465 and Ser467 Is Required for Smad2-Smad4 Complex Formation and Signaling

27 September 2017

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27 September 2017

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A mutation in the transforming growth factor beta type II receptor gene promoter associated with loss of gene expression

27 September 2017

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Partnership between DPC4 and SMAD proteins in TGF-beta signalling pathways.

27 September 2017

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Functional significance of Smad2 in regulating basal keratinocyte migration during wound healing

27 September 2017

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Transforming growth factor beta type I receptor kinase mutant associated with metastatic breast cancer.

30 May 2018

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Automation of nanoscale microcapillary liquid chromatography-tandem mass spectrometry with a vented column

30 May 2018

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Smad3 in the mammary epithelium has a nonredundant role in the induction of apoptosis, but not in the regulation of proliferation or differentiation by transforming growth factor-beta.

29 November 2018

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Novel inactivating mutations of transforming growth factor-beta type I receptor gene in head-and-neck cancer metastases

29 November 2018

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Transforming growth factor-beta receptor type I gene is frequently mutated in ovarian carcinomas.

29 November 2018

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29 November 2018

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Heterogeneities in the biological and biochemical functions of Smad2 and Smad4 mutants naturally occurring in human lung cancers

29 November 2018

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29 November 2018

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29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700048

Missense mutations of the transforming growth factor beta type II receptor in human head and neck squamous carcinoma cells.

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700048

A transforming growth factor beta receptor type II gene mutation common in colon and gastric but rare in endometrial cancers with microsatellite instability

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=2700048

Analysis of specific gene mutations in the transforming growth factor-beta signal transduction pathway in human ovarian cancer

29 November 2018

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18729074

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Mining genomes: correlating tandem mass spectra of modified and unmodified peptides to sequences in nucleotide databases

1 reference

PubMed

https://pubmed.ncbi.nlm.nih.gov/18729074

inferred from PubMed ID database lookup

12 December 2020

based on heuristic

Identifiers

DOI

10.1002/JCB.21860

1 reference

OpenCitations bibliographic resource ID

21 June 2017

2806989

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

1 reference

Consolidated OpenCitations Corpus – April 2017

OpenCitations bibliographic resource ID

2806989

1 reference