Evidence for in vivo phosphorylation of the Grb2 SH2-domain binding site on focal adhesion kinase by Src-family protein-tyrosine kinases (Q24336665)

GOA release 2020-03-11

D D Schlaepfer

1

D D

Schlaepfer

1 reference

PubMed publication ID

8816475

20 October 2023

T Hunter

series ordinal

2

author given names

T

author last names

Hunter

1 reference

PubMed publication ID

8816475

Molecular and Cellular Biology

20 October 2023

language of work or name

English

0 references

publication date

October 1996

0 references

published in

0 references

volume

16

0 references

issue

10

0 references

page(s)

5623-33

0 references

cites work

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Paxillin, a tyrosine phosphorylated focal adhesion-associated protein binds to the carboxyl terminal domain of focal adhesion kinase

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Tyrosine phosphorylation of focal adhesion kinase at sites in the catalytic domain regulates kinase activity: a role for Src family kinases

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Autophosphorylation of the focal adhesion kinase, pp125FAK, directs SH2-dependent binding of pp60src

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pp125FAK a structurally distinctive protein-tyrosine kinase associated with focal adhesions

19 March 2017

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Interaction of focal adhesion kinase with cytoskeletal protein talin

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Integrin-mediated signal transduction linked to Ras pathway by GRB2 binding to focal adhesion kinase

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Integrins and signal transduction pathways: the road taken

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7 April 2017

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Reduced cell motility and enhanced focal adhesion contact formation in cells from FAK-deficient mice

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27 September 2017

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Direct interaction of v-Src with the focal adhesion kinase mediated by the Src SH2 domain

27 September 2017

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Association of focal adhesion kinase with its potential substrate phosphatidylinositol 3-kinase

27 September 2017

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27 September 2017

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27 September 2017

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27 September 2017

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Integrin-dependent activation of MAP kinase: a link to shape-dependent cell proliferation

27 September 2017

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Stimulation of human monocytes with macrophage colony-stimulating factor induces a Grb2-mediated association of the focal adhesion kinase pp125FAK and dynamin

27 September 2017

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pp60c-src is a positive regulator of growth factor-induced cell scattering in a rat bladder carcinoma cell line

27 September 2017

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The alpha 5 beta 1 integrin supports survival of cells on fibronectin and up-regulates Bcl-2 expression

27 September 2017

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Suppression of ICE and apoptosis in mammary epithelial cells by extracellular matrix.

27 September 2017

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Association of the amino-terminal half of c-Src with focal adhesions alters their properties and is regulated by phosphorylation of tyrosine 527.

27 September 2017

1 reference

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27 September 2017

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Stable association of pp60src and pp59fyn with the focal adhesion-associated protein tyrosine kinase, pp125FAK.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231562

Focal adhesion protein-tyrosine kinase phosphorylated in response to cell attachment to fibronectin

27 September 2017

1 reference

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Dependence of cyclin E-CDK2 kinase activity on cell anchorage.

27 September 2017

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Cloning and Characterization of Cell Adhesion Kinase β, a Novel Protein-tyrosine Kinase of the Focal Adhesion Kinase Subfamily

27 September 2017

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Specific and redundant roles of Src and Fyn in organizing the cytoskeleton.

27 September 2017

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231562

Integrin-mediated tyrosine phosphorylation and cytokine message induction in monocytic cells. A possible signaling role for the Syk tyrosine kinase.

27 September 2017

1 reference

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Integrin-mediated cell adhesion promotes tyrosine phosphorylation of p130Cas, a Src homology 3-containing molecule having multiple Src homology 2-binding motifs

27 September 2017

1 reference

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Association of insulin receptor substrate-1 with integrins

27 September 2017

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Disruption of integrin function and induction of tyrosine phosphorylation by the autonomously expressed beta 1 integrin cytoplasmic domain

27 September 2017

1 reference

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Breaking the integrin hinge. A defined structural constraint regulates integrin signaling

27 September 2017

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Requirement for phosphatidylinositol 3'-kinase activity in platelet-derived growth factor-stimulated tyrosine phosphorylation of p125 focal adhesion kinase and paxillin

30 May 2018

1 reference

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A 50-kDa integrin-associated protein is required for integrin-regulated calcium entry in endothelial cells.

30 May 2018

1 reference

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Bombesin stimulation of p125 focal adhesion kinase tyrosine phosphorylation. Role of protein kinase C, Ca2 mobilization, and the actin cytoskeleton.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231562

A transmembrane-anchored chimeric focal adhesion kinase is constitutively activated and phosphorylated at tyrosine residues identical to pp125FAK.

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231562

Differential effects of platelet-derived growth factor BB on p125 focal adhesion kinase and paxillin tyrosine phosphorylation and on cell migration in rabbit aortic vascular smooth muscle cells and Swiss 3T3 fibroblasts

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231562

Lysophosphatidic acid stimulates tyrosine phosphorylation of focal adhesion kinase, paxillin, and p130. Signaling pathways and cross-talk with platelet-derived growth factor

30 May 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231562

The small GTP-binding protein Rho regulates a phosphatidylinositol 4-phosphate 5-kinase in mammalian cells

30 May 2018

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https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231562

Hepatocyte growth factor/scatter factor induces tyrosine phosphorylation of focal adhesion kinase (p125FAK) and promotes migration and invasion by oral squamous cell carcinoma cells

29 November 2018

1 reference

https://eutils.ncbi.nlm.nih.gov/entrez/eutils/elink.fcgi?dbfrom=pmc&linkname=pmc_refs_pubmed&retmode=json&id=231562

Cell adhesion or integrin clustering increases phosphorylation of a focal adhesion-associated tyrosine kinase

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