Crosstalk between leukemia-associated proteins MOZ and MLL regulates HOX gene expression in human cord blood CD34 cells (Q24336563)

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6 February 2020

title

Crosstalk between leukemia-associated proteins MOZ and MLL regulates HOX gene expression in human cord blood CD34 cells (English)

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6 February 2020

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1

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6 February 2020

Anne Largeot

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6 February 2020

Arnaud Jacquel

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6 February 2020

Eric Solary

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author name string

R Aucagne

3

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6 February 2020

B Lagrange

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6 February 2020

X-J Yang

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6 February 2020

J-N Bastie

8

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6 February 2020

L Delva

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language of work or name

English

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publication date

28 June 2010

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https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20581860 AND SRC:MED&resulttype=core&format=json

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volume

29

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issue

36

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page(s)

5019-5031

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Hox genes in hematopoiesis and leukemogenesis.

6 February 2020

cites work

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Transformation of myeloid progenitors by MLL oncoproteins is dependent on Hoxa7 and Hoxa9

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The t(7;11)(p15;p15) translocation in acute myeloid leukaemia fuses the genes for nucleoporin NUP98 and class I homeoprotein HOXA9

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The translocation t(8;16)(p11;p13) of acute myeloid leukaemia fuses a putative acetyltransferase to the CREB-binding protein

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Transcriptional regulation of the human MIP-1alpha promoter by RUNX1 and MOZ

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Gene expression profiling of acute myeloid leukemia with translocation t(8;16)(p11;p13) and MYST3-CREBBP rearrangement reveals a distinctive signature with a specific pattern of HOX gene expression.

31 March 2020

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The diverse functions of histone acetyltransferase complexes.

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The monocytic leukemia zinc finger protein MOZ is a histone acetyltransferase

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MOZ and MOZ-CBP cooperate with NF-kappaB to activate transcription from NF-kappaB-dependent promoters.

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Genomic characterization reveals a simple histone H4 acetylation code.

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Physical association and coordinate function of the H3 K4 methyltransferase MLL1 and the H4 K16 acetyltransferase MOF

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An Mll-dependent Hox program drives hematopoietic progenitor expansion

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MLL and CREB bind cooperatively to the nuclear coactivator CREB-binding protein

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NCOA3, a new fusion partner for MOZ/MYST3 in M5 acute myeloid leukemia

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Molecular classification of cancer: class discovery and class prediction by gene expression monitoring

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Methylation of histone H3R2 by PRMT6 and H3K4 by an MLL complex are mutually exclusive

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Linking the epigenetic 'language' of covalent histone modifications to cancer

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Mammalian Trithorax and polycomb-group homologues are antagonistic regulators of homeotic development

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MLL: a histone methyltransferase disrupted in leukemia

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Taspase1: a threonine aspartase required for cleavage of MLL and proper HOX gene expression

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Recognition of histone H3 lysine-4 methylation by the double tudor domain of JMJD2A

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Translating the Histone Code

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Unique and independent roles for MLL in adult hematopoietic stem cells and progenitors

31 March 2020

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MOZ is essential for maintenance of hematopoietic stem cells

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MOZ-TIF2 inhibits transcription by nuclear receptors and p53 by impairment of CBP function

31 March 2020

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Activation of AML1-mediated transcription by MOZ and inhibition by the MOZ-CBP fusion protein

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New insights into MLL gene rearranged acute leukemias using gene expression profiling: shared pathways, lineage commitment, and partner genes

31 March 2020

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Chromatin modifications and their function

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MLL translocations, histone modifications and leukaemia stem-cell development

31 March 2020

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Homeobox genes and axial patterning

31 March 2020

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Mll has a critical role in fetal and adult hematopoietic stem cell self-renewal.

31 March 2020

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MLL targets SET domain methyltransferase activity to Hox gene promoters

31 March 2020

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MLL associates specifically with a subset of transcriptionally active target genes

31 March 2020

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Expression pattern of dd4, a sole member of the d4 family of transcription factors in Drosophila melanogaster.

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31 March 2020

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MOZ and MORF histone acetyltransferases interact with the Runt-domain transcription factor Runx2

31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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31 March 2020

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MOZ and MORF, two large MYSTic HATs in normal and cancer stem cells

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Altered Hox expression and segmental identity in Mll-mutant mice

31 March 2020

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31 March 2020

Identifiers

DOI

10.1038/ONC.2010.254

1 reference

https://www.ebi.ac.uk/europepmc/webservices/rest/search?query=EXT_ID:20581860 AND SRC:MED&resulttype=core&format=json

Dimensions Publication ID

6 February 2020

1016439650

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1 reference