The ubiquitin ligase RNF5 regulates antiviral responses by mediating degradation of the adaptor protein MITA (Q24321482)

protein K48-linked ubiquitination

GOA release 2020-03-11

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GOA release 2020-03-11

7

Yan-Yi Wang

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author name string

Bo Zhong

1

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Lu Zhang

2

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Caoqi Lei

3

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Ying Li

4

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Ai-Ping Mao

5

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Yan Yang

6

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Xiao-Lian Zhang

8

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Hong-Bing Shu

Identification and characterization of MAVS, a mitochondrial antiviral signaling protein that activates NF-kappaB and IRF 3

9

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language of work or name

English

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publication date

20 March 2009

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published in

Immunity

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volume

30

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issue

3

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page(s)

397-407

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cites work

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The specific and essential role of MAVS in antiviral innate immune responses

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Type I interferon [corrected] gene induction by the interferon regulatory factor family of transcription factors

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TRADD Protein Is an Essential Component of the RIG-like Helicase Antiviral Pathway

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The adaptor protein MITA links virus-sensing receptors to IRF3 transcription factor activation

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VISA is an adapter protein required for virus-triggered IFN-beta signaling

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Negative feedback regulation of cellular antiviral signaling by RBCK1-mediated degradation of IRF3

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Cardif is an adaptor protein in the RIG-I antiviral pathway and is targeted by hepatitis C virus

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Critical role of TRAF3 in the Toll-like receptor-dependent and -independent antiviral response

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Differential roles of MDA5 and RIG-I helicases in the recognition of RNA viruses

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NLRX1 is a regulator of mitochondrial antiviral immunity

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STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

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The RNA helicase RIG-I has an essential function in double-stranded RNA-induced innate antiviral responses

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IPS-1, an adaptor triggering RIG-I- and Mda5-mediated type I interferon induction

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Negative regulation of interferon-regulatory factor 3-dependent innate antiviral response by the prolyl isomerase Pin1.

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The NEMO adaptor bridges the nuclear factor-kappaB and interferon regulatory factor signaling pathways

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TICAM-1, an adaptor molecule that participates in Toll-like receptor 3-mediated interferon-beta induction

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Regulation of antiviral responses by a direct and specific interaction between TRAF3 and Cardif

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Negative regulation of the RIG-I signaling by the ubiquitin ligase RNF125

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Role of adaptor TRIF in the MyD88-independent toll-like receptor signaling pathway

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Involvement of the IkappaB kinase (IKK)-related kinases tank-binding kinase 1/IKKi and cullin-based ubiquitin ligases in IFN regulatory factor-3 degradation

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The E3 ubiquitin ligase Ro52 negatively regulates IFN-beta production post-pathogen recognition by polyubiquitin-mediated degradation of IRF3

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